Inducible nitric oxide synthase: Regulation, structure, and inhibition MA Cinelli, HT Do, GP Miley, RB Silverman Medicinal research reviews, 2019 | 723 | 2019 |
Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain P Mukherjee, MA Cinelli, S Kang, RB Silverman Chemical Society Reviews 43 (19), 6814-6838, 2014 | 171 | 2014 |
Visible light mediated activation and O-glycosylation of thioglycosides WJ Wever, MA Cinelli, AA Bowers Organic letters 15 (1), 30-33, 2012 | 111 | 2012 |
Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors MA Cinelli, A Morrell, TS Dexheimer, ES Scher, Y Pommier, M Cushman Journal of medicinal chemistry 51 (15), 4609-4619, 2008 | 98 | 2008 |
Structures of human constitutive nitric oxide synthases H Li, J Jamal, C Plaza, SH Pineda, G Chreifi, Q Jing, MA Cinelli, ... Acta Crystallographica Section D: Biological Crystallography 70 (10), 2667-2674, 2014 | 70 | 2014 |
Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl) aromathecins as topoisomerase I inhibitors: Investigating the hypothesis of shared structure–activity … MA Cinelli, B Cordero, TS Dexheimer, Y Pommier, M Cushman Bioorganic & medicinal chemistry 17 (20), 7145-7155, 2009 | 67 | 2009 |
Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of … MA Cinelli, PVN Reddy, PC Lv, JH Liang, L Chen, K Agama, Y Pommier, ... Journal of medicinal chemistry 55 (24), 10844-10862, 2012 | 66 | 2012 |
Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding … KE Peterson, MA Cinelli, AE Morrell, A Mehta, TS Dexheimer, K Agama, ... Journal of medicinal chemistry 54 (14), 4937-4953, 2011 | 63 | 2011 |
Alkaloids of the Genus Datura: Review of a Rich Resource for Natural Product Discovery MA Cinelli, AD Jones Molecules 26 (9), 2629, 2021 | 58 | 2021 |
Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition MA Cinelli, H Li, G Chreifi, P Martásek, LJ Roman, TL Poulos, ... Journal of medicinal chemistry 57 (4), 1513-1530, 2014 | 53 | 2014 |
Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation Y Wang, J Yang, W Wang, KZ Sanidad, MA Cinelli, D Wan, SH Hwang, ... Proceedings of the National Academy of Sciences 117 (15), 8431-8436, 2020 | 46 | 2020 |
Topoisomerase 1B poisons: Over a half‐century of drug leads, clinical candidates, and serendipitous discoveries MA Cinelli Medicinal research reviews 39 (4), 1294-1337, 2019 | 45 | 2019 |
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors MA Cinelli, H Li, G Chreifi, TL Poulos, RB Silverman Journal of Medicinal Chemistry, 2017 | 44 | 2017 |
Correction to Phenyl Ether-and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase MA Cinelli, H Li, AV Pensa, S Kang, LJ Roman, P Martásek, TL Poulos, ... Journal of medicinal chemistry 59 (3), 1246-1246, 2016 | 36* | 2016 |
Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors AV Pensa, MA Cinelli, H Li, G Chreifi, P Mukherjee, LJ Roman, ... Journal of Medicinal Chemistry, 2017 | 27 | 2017 |
The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode MA Cinelli, AE Morrell, TS Dexheimer, K Agama, S Agrawal, Y Pommier, ... Bioorganic & medicinal chemistry 18 (15), 5535-5552, 2010 | 27 | 2010 |
Nitric oxide synthase as a target for methicillin-resistant Staphylococcus aureus JK Holden, S Kang, FC Beasley, MA Cinelli, H Li, SG Roy, D Dejam, ... Chemistry & biology 22 (6), 785-792, 2015 | 24 | 2015 |
First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate MA Cinelli, CT Reidl, H Li, G Chreifi, TL Poulos, RB Silverman Journal of Medicinal Chemistry, 2020 | 21 | 2020 |
Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors JK Holden, MC Lewis, MA Cinelli, Z Abdullatif, AV Pensa, RB Silverman, ... Biochemistry 55 (39), 5587-5594, 2016 | 20 | 2016 |
Cancer chemopreventive potential of aromathecins and phenazines, novel natural product derivatives L Marler, M Conda-Sheridan, MA Cinelli, AE Morrell, M Cushman, L Chen, ... Anticancer research 30 (12), 4873-4882, 2010 | 20 | 2010 |