High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22 M Gulhane, L Murray, R Lourie, H Tong, YH Sheng, R Wang, A Kang, ... Scientific reports 6 (1), 28990, 2016 | 358 | 2016 |
Muc5ac: a critical component mediating the rejection of enteric nematodes SZ Hasnain, CM Evans, M Roy, AL Gallagher, KN Kindrachuk, L Barron, ... Journal of Experimental Medicine 208 (5), 893-900, 2011 | 345 | 2011 |
The interplay between endoplasmic reticulum stress and inflammation SZ Hasnain, R Lourie, I Das, ACH Chen, MA McGuckin Immunology and cell biology 90 (3), 260-270, 2012 | 314 | 2012 |
Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes SZ Hasnain, JB Prins, MA McGuckin Journal of molecular endocrinology 56 (2), R33-R54, 2016 | 283 | 2016 |
Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress SZ Hasnain, DJ Borg, BE Harcourt, H Tong, YH Sheng, CP Ng, I Das, ... Nature medicine 20 (12), 1417-1426, 2014 | 271 | 2014 |
IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells SZ Hasnain, S Tauro, I Das, H Tong, ACH Chen, PL Jeffery, V McDonald, ... Gastroenterology 144 (2), 357-368. e9, 2013 | 250 | 2013 |
Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection SZ Hasnain, H Wang, JE Ghia, N Haq, Y Deng, A Velcich, RK Grencis, ... Gastroenterology 138 (5), 1763-1771. e5, 2010 | 236 | 2010 |
Mucins in inflammatory bowel diseases and colorectal cancer YH Sheng, SZ Hasnain, THJ Florin, MA McGuckin Journal of gastroenterology and hepatology 27 (1), 28-38, 2012 | 223 | 2012 |
Interleukin‐23 mediates the intestinal response to microbial β‐1, 3‐glucan and the development of spondyloarthritis pathology in SKG mice H Benham, LM Rehaume, SZ Hasnain, J Velasco, AC Baillet, M Ruutu, ... Arthritis & rheumatology 66 (7), 1755-1767, 2014 | 208 | 2014 |
ZAP‐70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice LM Rehaume, S Mondot, D Aguirre de Cárcer, J Velasco, H Benham, ... Arthritis & rheumatology 66 (10), 2780-2792, 2014 | 188 | 2014 |
Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins I Das, CW Png, I Oancea, SZ Hasnain, R Lourie, M Proctor, RD Eri, ... Journal of Experimental Medicine 210 (6), 1201-1216, 2013 | 129 | 2013 |
Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier SZ Hasnain, MA McGuckin, RK Grencis, DJ Thornton Public Library of Science 6 (10), e1856, 2012 | 128 | 2012 |
A new role for mucins in immunity: insights from gastrointestinal nematode infection SZ Hasnain, AL Gallagher, RK Grencis, DJ Thornton The international journal of biochemistry & cell biology 45 (2), 364-374, 2013 | 126 | 2013 |
Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis KA Ramsey, ACH Chen, G Radicioni, R Lourie, M Martin, A Broomfield, ... American journal of respiratory and critical care medicine 201 (6), 661-670, 2020 | 109 | 2020 |
MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target YH Sheng, Y He, SZ Hasnain, R Wang, H Tong, DT Clarke, R Lourie, ... Oncogene 36 (5), 700-713, 2017 | 92 | 2017 |
Changes in the mucosal barrier during acute and chronic Trichuris muris infection SZ Hasnain, DJ Thornton, RK Grencis Parasite immunology 33 (1), 45-55, 2011 | 90 | 2011 |
Acute graft-versus-host disease is regulated by an IL-17–sensitive microbiome A Varelias, KL Ormerod, MD Bunting, M Koyama, KH Gartlan, RD Kuns, ... Blood, The Journal of the American Society of Hematology 129 (15), 2172-2185, 2017 | 76 | 2017 |
Mucus and mucins: the underappreciated host defence system YH Sheng, SZ Hasnain Frontiers in Cellular and Infection Microbiology 12, 856962, 2022 | 68 | 2022 |
Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion SZ Hasnain, PA Dawson, R Lourie, P Hutson, H Tong, RK Grencis, ... PLoS Pathogens 13 (2), e1006218, 2017 | 59 | 2017 |
Human diseases, immunity and the oral microbiota—Insights gained from metagenomic studies A Idris, SZ Hasnain, LZ Huat, D Koh Oral Science International 14 (2), 27-32, 2017 | 56 | 2017 |