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Balaguru Ravikumar
Balaguru Ravikumar
Institute for Molecular Medicine, University of Helsinki
Dirección de correo verificada de helsinki.fi
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Drug target commons: a community effort to build a consensus knowledge base for drug-target interactions
J Tang, B Ravikumar, Z Alam, A Rebane, M Vähä-Koskela, G Peddinti, ...
Cell chemical biology 25 (2), 224-229. e2, 2018
1542018
Computational-experimental approach to drug-target interaction mapping: a case study on kinase inhibitors
A Cichonska, B Ravikumar, E Parri, S Timonen, T Pahikkala, A Airola, ...
PLoS computational biology 13 (8), e1005678, 2017
1252017
Improving the efficacy-safety balance of polypharmacology in multi-target drug discovery
B Ravikumar, T Aittokallio
Expert opinion on drug discovery 13 (2), 179-192, 2018
822018
Crowdsourced mapping of unexplored target space of kinase inhibitors
A Cichońska, B Ravikumar, RJ Allaway, F Wan, S Park, O Isayev, S Li, ...
Nature communications 12 (1), 3307, 2021
762021
Drug Target Commons 2.0: a community platform for systematic analysis of drug–target interaction profiles
ZR Tanoli, Z Alam, M Vähä-Koskela, B Ravikumar, A Malyutina, A Jaiswal, ...
Database 2018, bay083, 2018
652018
Chemogenomic analysis of the druggable kinome and its application to repositioning and lead identification studies
B Ravikumar, S Timonen, Z Alam, E Parri, K Wennerberg, T Aittokallio
Cell chemical biology 26 (11), 1608-1622. e6, 2019
222019
AI for targeted polypharmacology: The next frontier in drug discovery
A Cichońska, B Ravikumar, R Rahman
Current Opinion in Structural Biology 84, 102771, 2024
202024
C-SPADE: a web-tool for interactive analysis and visualization of drug screening experiments through compound-specific bioactivity dendrograms
B Ravikumar, Z Alam, G Peddinti, T Aittokallio
Nucleic acids research 45 (W1), W495-W500, 2017
172017
Investigating the conformational landscape of AlphaFold2-predicted protein kinase structures
C Al-Masri, F Trozzi, SH Lin, O Tran, N Sahni, M Patek, A Cichonska, ...
Bioinformatics Advances 3 (1), vbad129, 2023
142023
Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells
P Athanasiadis, B Ravikumar, RJR Elliott, JC Dawson, NO Carragher, ...
Iscience 26 (7), 2023
32023
Leveraging multiple data types for improved compound-kinase bioactivity prediction
R Theisen, T Wang, B Ravikumar, R Rahman, A Cichońska
Nature Communications 15 (1), 7596, 2024
22024
Optimized chemogenomic library design strategies for precision oncology
P Athanasiadis, B Ravikumar, NO Carragher, PA Clemons, T Johanssen, ...
bioRxiv, 2020.11. 30.403329, 2020
12020
Advancements in Rational Multi‐Targeted Drug Discovery: Improving the Efficacy‐Safety Balance of Small Molecule Cancer Therapeutics
B Ravikumar, A Cichońska, N Sahni, T Aittokallio, R Rahman
Polypharmacology: Strategies for Multi‐Target Drug Discovery, 109-125, 2025
2025
CCGM: a Compound Coarse Grain Model representation for enhanced chemotype exploration, annotation and screening
N Sahni, M Patek, R Rahman, B Ravikumar
bioRxiv, 2024.12. 16.628696, 2024
2024
Leveraging Machine Learning and AlphaFold2 Steering to Discover State-Specific Inhibitors Across the Kinome
F Trozzi, O Tran, C Al Masri, SH Lin, B Ravikumar, R Rahman
bioRxiv, 2024.08. 16.608358, 2024
2024
Computational frameworks to aid pharmacological studies: Tools, Databases and Prediction models
B Ravikumar
Helsingin yliopisto, 2020
2020
Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions
B Ravikumar, G Repasky, K Wennerberg, T Aittokallio
2018
TOOLS, DATABASESAND PREDICTION MODELS
B Ravikumar
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Artículos 1–18