| Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers M Gu, NY Shao, S Sa, D Li, V Termglinchan, M Ameen, I Karakikes, ... Cell stem cell 20 (4), 490-504. e5, 2017 | 213 | 2017 |
| Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ... Cell stem cell 17 (1), 89-100, 2015 | 206 | 2015 |
| Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ... Nature 572 (7769), 335-340, 2019 | 196 | 2019 |
| Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis JM Churko, P Garg, B Treutlein, M Venkatasubramanian, H Wu, J Lee, ... Nature communications 9 (1), 4906, 2018 | 195 | 2018 |
| Human-induced pluripotent stem cell model of trastuzumab-induced cardiac dysfunction in patients with breast cancer T Kitani, SG Ong, CK Lam, JW Rhee, JZ Zhang, A Oikonomopoulos, N Ma, ... Circulation 139 (21), 2451-2465, 2019 | 178 | 2019 |
| Large-scale single-cell RNA-seq reveals molecular signatures of heterogeneous populations of human induced pluripotent stem cell-derived endothelial cells DT Paik, L Tian, J Lee, N Sayed, IY Chen, S Rhee, JW Rhee, Y Kim, ... Circulation research 123 (4), 443-450, 2018 | 152 | 2018 |
| Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients H Wu, H Yang, JW Rhee, JZ Zhang, CK Lam, K Sallam, ACY Chang, ... European heart journal 40 (45), 3685-3695, 2019 | 129 | 2019 |
| A premature termination codon mutation in MYBPC3 causes hypertrophic cardiomyopathy via chronic activation of nonsense-mediated decay T Seeger, R Shrestha, CK Lam, C Chen, WL McKeithan, E Lau, ... Circulation 139 (6), 799-811, 2019 | 125 | 2019 |
| Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem … AD Ebert, K Kodo, P Liang, H Wu, BC Huber, J Riegler, J Churko, J Lee, ... Science translational medicine 6 (255), 255ra130-255ra130, 2014 | 125 | 2014 |
| Transcriptional repression of cancer stem cell marker CD133 by tumor suppressor p53 EK Park, JC Lee, JW Park, SY Bang, SA Yi, BK Kim, JH Park, SH Kwon, ... Cell death & disease 6 (11), e1964-e1964, 2015 | 108 | 2015 |
| Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness S Lee, V Serpooshan, X Tong, S Venkatraman, M Lee, J Lee, O Chirikian, ... Biomaterials 131, 111-120, 2017 | 96 | 2017 |
| Novel codon-optimized mini-intronic plasmid for efficient, inexpensive and xeno-free induction of pluripotency S Diecke, J Lu, J Lee, V Termglinchan, NG Kooreman, PW Burridge, ... Scientific reports 5 (1), 8081, 2015 | 86 | 2015 |
| S6K1 phosphorylation of H2B mediates EZH2 trimethylation of H3: a determinant of early adipogenesis SA Yi, SH Um, J Lee, JH Yoo, SY Bang, EK Park, MG Lee, KH Nam, ... Molecular cell 62 (3), 443-452, 2016 | 82 | 2016 |
| Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to … JS You, JK Kang, EK Lee, JC Lee, SH Lee, YJ Jeon, DH Koh, SH Ahn, ... Oncogene 27 (10), 1376-1386, 2008 | 79 | 2008 |
| Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells: involvement of Nanog suppression JS You, JK Kang, DW Seo, JH Park, JW Park, JC Lee, YJ Jeon, EJ Cho, ... Cancer research 69 (14), 5716-5725, 2009 | 73 | 2009 |
| Protein L-isoaspartyl methyltransferase regulates p53 activity JC Lee, SU Kang, Y Jeon, JW Park, JS You, SW Ha, N Bae, G Lubec, ... Nature communications 3 (1), 927, 2012 | 70 | 2012 |
| Recent technological updates and clinical applications of induced pluripotent stem cells S Diecke, SM Jung, J Lee, JH Ju The Korean journal of internal medicine 29 (5), 547, 2014 | 67 | 2014 |
| A comprehensive TALEN-based knockout library for generating human-induced pluripotent stem cell–based models for cardiovascular diseases I Karakikes, V Termglinchan, DA Cepeda, J Lee, S Diecke, A Hendel, ... Circulation Research 120 (10), 1561-1571, 2017 | 65 | 2017 |
| Infection of brain organoids and 2D cortical neurons with SARS-CoV-2 pseudovirus SA Yi, KH Nam, J Yun, D Gim, D Joe, YH Kim, HJ Kim, JW Han, J Lee Viruses 12 (9), 1004, 2020 | 59 | 2020 |
| Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis J Lee, Y Kim, H Yi, S Diecke, J Kim, H Jung, YA Rim, SM Jung, M Kim, ... Arthritis research & therapy 16, 1-8, 2014 | 55 | 2014 |
Joseph C. WuStanford University, Director, Cardiovascular Institute, Professor of Medicine & Radiology,Dirección de correo verificada de stanford.edu
