The landscape of accessible chromatin in mammalian preimplantation embryos J Wu, BO Huang, HE Chen, Q Yin, Y Liu, Y Xiang, B Zhang, B Liu, ... Nature 534 (7609), 652-657, 2016 | 633 | 2016 |
Chromatin analysis in human early development reveals epigenetic transition during ZGA J Wu, J Xu, B Liu, G Yao, P Wang, Z Lin, B Huang, X Wang, T Li, S Shi, ... Nature 557 (7704), 256-260, 2018 | 300 | 2018 |
Resetting histone modifications during human parental-to-zygotic transition W Xia, J Xu, G Yu, G Yao, K Xu, X Ma, N Zhang, B Liu, T Li, Z Lin, X Chen, ... Science 365 (6451), 353-360, 2019 | 215 | 2019 |
The landscape of RNA Pol II binding reveals a stepwise transition during ZGA B Liu, Q Xu, Q Wang, S Feng, F Lai, P Wang, F Zheng, Y Xiang, J Wu, ... Nature 587 (7832), 139-144, 2020 | 107 | 2020 |
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development Z Xiong, K Xu, Z Lin, F Kong, Q Wang, Y Quan, Q Sha, F Li, Z Zou, L Liu, ... Nature Cell Biology 24 (6), 968-980, 2022 | 93 | 2022 |
Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation Z Zou, C Zhang, Q Wang, Z Hou, Z Xiong, F Kong, Q Wang, J Song, B Liu, ... Science 378 (6615), abo7923, 2022 | 92 | 2022 |
Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency Y Xiang, Y Zhang, Q Xu, C Zhou, B Liu, Z Du, K Zhang, B Zhang, X Wang, ... Nature genetics 52 (1), 95-105, 2020 | 83 | 2020 |
Generation and characterization of stable pig pregastrulation epiblast stem cell lines M Zhi, J Zhang, Q Tang, D Yu, S Gao, D Gao, P Liu, J Guo, T Hai, J Gao, ... Cell Research 32 (4), 383-400, 2022 | 66 | 2022 |
A growth factor-free culture system underscores the coordination between Wnt and BMP signaling in Lgr5+ intestinal stem cell maintenance Y Li, Y Liu, B Liu, J Wang, S Wei, Z Qi, S Wang, W Fu, YG Chen Cell Discovery 4 (1), 49, 2018 | 63 | 2018 |
OBOX regulates mouse zygotic genome activation and early development S Ji, F Chen, P Stein, J Wang, Z Zhou, L Wang, Q Zhao, Z Lin, B Liu, K Xu, ... Nature 620 (7976), 1047-1053, 2023 | 61 | 2023 |
The Wnt signaling antagonist Dapper1 accelerates Dishevelled2 degradation via promoting its ubiquitination and aggregate-induced autophagy B Ma, B Liu, W Cao, C Gao, Z Qi, Y Ning, YG Chen Journal of Biological Chemistry 290 (19), 12346-12354, 2015 | 51 | 2015 |
Receptor for activated C kinase 1 (RACK1) promotes Dishevelled protein degradation via autophagy and antagonizes Wnt signaling M Cheng, H Xue, W Cao, W Li, H Chen, B Liu, B Ma, X Yan, YG Chen Journal of Biological Chemistry 291 (24), 12871-12879, 2016 | 31 | 2016 |
NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos F Lai, L Li, X Hu, B Liu, Z Zhu, L Liu, Q Fan, H Tian, K Xu, X Lu, Q Li, ... Cell Research 33 (12), 952-966, 2023 | 26* | 2023 |
Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos L Li, F Lai, X Hu, B Liu, X Lu, Z Lin, L Liu, Y Xiang, T Frum, MA Halbisen, ... Science 382 (6676), eadi5516, 2023 | 17 | 2023 |
Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos L Li, F Lai, L Liu, X Lu, X Hu, B Liu, Z Lin, Q Fan, F Kong, Q Xu, W Xie Nature Structural & Molecular Biology 31 (6), 950-963, 2024 | 14 | 2024 |
Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs X Wu, H Zhang, B Zhang, Y Zhang, Q Wang, W Shen, X Wu, L Li, W Xia, ... Science Advances 7 (52), eabl3858, 2021 | 14 | 2021 |
High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis XL Gao, WJ Tian, B Liu, J Wu, W Xie, Q Shen Journal of Biological Chemistry 295 (2), 468-480, 2020 | 14 | 2020 |
H3K18ac primes mesendodermal differentiation upon nodal signaling M Luo, J Bai, B Liu, P Yan, F Zuo, H Sun, Y Sun, X Xu, Z Song, Y Yang, ... Stem cell reports 13 (4), 642-656, 2019 | 14 | 2019 |
Purification, crystallization and preliminary X-ray analysis of nonstructural protein 2 (nsp2) from avian infectious bronchitis virus K Yu, Z Ming, Y Li, C Chen, Z Bao, Z Ren, B Liu, W Tao, Z Rao, Z Lou Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 14 | 2012 |
Activin/Smad2 and Wnt/β-catenin up-regulate HAS2 and ALDH3A2 to facilitate mesendoderm differentiation of human embryonic stem cells X Xu, L Wang, B Liu, W Xie, YG Chen Journal of Biological Chemistry 293 (48), 18444-18453, 2018 | 11 | 2018 |