Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities NJ Lanning, JP Castle, SJ Singh, AN Leon, EA Tovar, A Sanghera, ... Cancer & metabolism 5, 1-14, 2017 | 183 | 2017 |
Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to … LD Engstrom, R Aranda, M Lee, EA Tovar, CJ Essenburg, Z Madaj, ... Clinical Cancer Research 23 (21), 6661-6672, 2017 | 138 | 2017 |
MET in human cancer: germline and somatic mutations EA Tovar, CR Graveel Annals of translational medicine 5 (10), 2017 | 97 | 2017 |
Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers ES Linklater, EA Tovar, CJ Essenburg, L Turner, Z Madaj, ME Winn, ... Oncotarget 7 (43), 69903, 2016 | 68 | 2016 |
Cabozantinib (XL184) inhibits growth and invasion of preclinical TNBC models M Sameni, EA Tovar, CJ Essenburg, A Chalasani, ES Linklater, ... Clinical Cancer Research 22 (4), 923-934, 2016 | 56 | 2016 |
NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer PS Dischinger, EA Tovar, CJ Essenburg, ZB Madaj, EE Gardner, ... NPJ breast cancer 4 (1), 29, 2018 | 52 | 2018 |
Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors JD Peacock, MG Pridgeon, EA Tovar, CJ Essenburg, M Bowman, Z Madaj, ... Cancer research 78 (13), 3672-3687, 2018 | 40 | 2018 |
Convergence of eicosanoid and integrin biology: 12-lipoxygenase seeks a partner K Tang, Y Cai, S Joshi, E Tovar, SC Tucker, KR Maddipati, JD Crissman, ... Molecular cancer 14, 1-13, 2015 | 33 | 2015 |
In vivo Efficacy Studies in Cell Line and Patient-derived Xenograft Mouse Models EA Tovar, CJ Essenburg, C Graveel Bio-protocol 7 (1), e2100-e2100, 2017 | 5 | 2017 |
NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer. NPJ Breast Cancer. 2018; 4: 29 PS Dischinger, EA Tovar, CJ Essenburg, ZB Madaj, EE Gardner, ... | 5 | |
NF1 deficiency drives metabolic reprogramming in ER+ breast cancer RRJ House, EA Tovar, LN Redlon, CJ Essenburg, PS Dischinger, AE Ellis, ... Molecular Metabolism 80, 101876, 2024 | 4 | 2024 |
Dissecting the rat mammary gland: Isolation, characterization, and culture of purified mammary epithelial cells and fibroblasts EA Tovar, R Sheridan, CJ Essenburg, PS Dischinger, M Arumugam, ... Bio-protocol 10 (22), e3818-e3818, 2020 | 4 | 2020 |
Nf1 deficiency accelerates mammary development and promotes luminal-basal plasticity EA Tovar, M Arumugam, CJ Essenburg, PS Dischinger, JL Grit, ... bioRxiv, 2022.12. 22.520633, 2022 | 2 | 2022 |
Genomic MET amplification occurs early in NF1-related malignant peripheral nerve sheath tumor (MPNST) progression and is a potent therapeutic target JD Peacock, MG Pridgeon, EA Tovar, CJ Essenburg, M Bowman, Z Madaj, ... bioRxiv, 199000, 2017 | 2 | 2017 |
p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs JL Grit, LE McGee, EA Tovar, CJ Essenburg, E Wolfrum, I Beddows, ... Oncogene 43 (19), 1411-1430, 2024 | 1 | 2024 |
Oncogenic RAS-MET signal interactions are modulated by P53 status in NF1-related MPNSTs MG Pridgeon, EA Tovar, CJ Essenburg, Z Madaj, EA Boguslawski, ... bioRxiv, 199026, 2017 | 1 | 2017 |
Abstract B19: MET and IL6 signaling in triple-negative breast cancer EA Tovar, M Sameni, CJ Essenburg, A Chalasani, ES Linklater, ... Molecular Cancer Research 14 (2_Supplement), B19-B19, 2016 | 1 | 2016 |
Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases A Shemorry, W Besten, MM Mulvihill, CJ Essenburg, N Blaquiere, ... bioRxiv, 2024.06. 09.595178, 2024 | | 2024 |
Nf1 deficiency modulates the stromal environment in the pretumorigenic rat mammary gland M Arumugam, EA Tovar, CJ Essenburg, PS Dischinger, I Beddows, ... Frontiers in Cell and Developmental Biology 12, 1375441, 2024 | | 2024 |
Nf1 Deficiency Increases Mammary Collagen Deposition and Restricts Adipocyte Differentiation Before Tumor Formation M Arumugam, EA Tovar, CJ Essenburg, PS Dischinger, I Beddows, ... bioRxiv, 2023.06. 01.539442, 2023 | | 2023 |