| Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases M Bucciantini, E Giannoni, F Chiti, F Baroni, L Formigli, J Zurdo, N Taddei, ... nature 416 (6880), 507-511, 2002 | 3066 | 2002 |
| Prediction of “aggregation-prone” and “aggregation-susceptible” regions in proteins associated with neurodegenerative diseases AP Pawar, KF Dubay, J Zurdo, F Chiti, M Vendruscolo, CM Dobson Journal of molecular biology 350 (2), 379-392, 2005 | 729 | 2005 |
| Cryo‐electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing JL Jimenez, JI Guijarro, E Orlova, J Zurdo, CM Dobson, M Sunde, ... The EMBO journal, 1999 | 637 | 1999 |
| Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy M Bouchard, J Zurdo, EJ Nettleton, CM Dobson, CV Robinson Protein Science 9 (10), 1960-1967, 2000 | 577 | 2000 |
| Formation and seeding of amyloid fibrils from wild-type hen lysozyme and a peptide fragment from the β-domain MRH Krebs, DK Wilkins, EW Chung, MC Pitkeathly, AK Chamberlain, ... Journal of molecular biology 300 (3), 541-549, 2000 | 504 | 2000 |
| De novo designed peptide-based amyloid fibrils M López de la Paz, K Goldie, J Zurdo, E Lacroix, CM Dobson, A Hoenger, ... Proceedings of the National Academy of Sciences 99 (25), 16052-16057, 2002 | 438 | 2002 |
| Molecular recycling within amyloid fibrils N Carulla, GL Caddy, DR Hall, J Zurdo, M Gairí, M Feliz, E Giralt, ... Nature 436 (7050), 554-558, 2005 | 423 | 2005 |
| Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains KF DuBay, AP Pawar, F Chiti, J Zurdo, CM Dobson, M Vendruscolo Journal of molecular biology 341 (5), 1317-1326, 2004 | 391 | 2004 |
| Amyloid fibril formation and seeding by wild-type human lysozyme and its disease-related mutational variants LA Morozova-Roche, J Zurdo, A Spencer, W Noppe, V Receveur, ... Journal of structural biology 130 (2-3), 339-351, 2000 | 388 | 2000 |
| A highly amyloidogenic region of hen lysozyme E Frare, PP De Laureto, J Zurdo, CM Dobson, A Fontana Journal of molecular biology 340 (5), 1153-1165, 2004 | 319 | 2004 |
| Identification of a novel human islet amyloid polypeptide β-sheet domain and factors influencing fibrillogenesis ETAS Jaikaran, CE Higham, LC Serpell, J Zurdo, M Gross, A Clark, ... Journal of molecular biology 308 (3), 515-525, 2001 | 308 | 2001 |
| Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case S Ventura, J Zurdo, S Narayanan, M Parreño, R Mangues, B Reif, F Chiti, ... Proceedings of the National Academy of Sciences 101 (19), 7258-7263, 2004 | 298 | 2004 |
| Transition from natively unfolded to folded state induced by desiccation in an anhydrobiotic nematode protein K Goyal, L Tisi, A Basran, J Browne, A Burnell, J Zurdo, A Tunnacliffe Journal of Biological Chemistry 278 (15), 12977-12984, 2003 | 269 | 2003 |
| Dependence on solution conditions of aggregation and amyloid formation by an SH3 domain J Zurdo, JI Guijarro, JL Jiménez, HR Saibil, CM Dobson Journal of molecular biology 311 (2), 325-340, 2001 | 267 | 2001 |
| Ultrastructural organization of amyloid fibrils byatomic force microscopy AK Chamberlain, CE MacPhee, J Zurdo, LA Morozova-Roche, HAO Hill, ... Biophysical journal 79 (6), 3282-3293, 2000 | 244 | 2000 |
| Exploring amyloid formation by a de novo design RA Kammerer, D Kostrewa, J Zurdo, A Detken, C García-Echeverría, ... Proceedings of the National Academy of Sciences 101 (13), 4435-4440, 2004 | 197 | 2004 |
| Protein folding and misfolding: a paradigm of self–assembly and regulation in complex biological systems M Vendruscolo, J Zurdo, CE MacPhee, CM Dobson Philosophical Transactions of the Royal Society of London. Series A …, 2003 | 196 | 2003 |
| Preparation and characterization of purified amyloid fibrils J Zurdo, JI Guijarro, CM Dobson Journal of the American Chemical Society 123 (33), 8141-8142, 2001 | 152 | 2001 |
| Protein engineering as a strategy to avoid formation of amyloid fibrils V Villegas, J Zurdo, VV Filimonov, FX Avilés, CM Dobson, L Serrano Protein Science 9 (9), 1700-1708, 2000 | 151 | 2000 |
| Rational design of aggregation-resistant bioactive peptides: reengineering human calcitonin SB Fowler, S Poon, R Muff, F Chiti, CM Dobson, J Zurdo Proceedings of the National Academy of Sciences 102 (29), 10105-10110, 2005 | 135 | 2005 |