Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease DB Beck, MA Ferrada, KA Sikora, AK Ombrello, JC Collins, W Pei, ... New England Journal of Medicine 383 (27), 2628-2638, 2020 | 919 | 2020 |
Assembly and function of heterotypic ubiquitin chains in cell-cycle and protein quality control RG Yau, K Doerner, ER Castellanos, DL Haakonsen, A Werner, N Wang, ... Cell 171 (4), 918-933. e20, 2017 | 323 | 2017 |
Cell-fate determination by ubiquitin-dependent regulation of translation A Werner, S Iwasaki, CA McGourty, S Medina-Ruiz, N Teerikorpi, ... Nature 525 (7570), 523-527, 2015 | 191 | 2015 |
Novel somatic mutations in UBA1 as a cause of VEXAS syndrome JA Poulter, JC Collins, C Cargo, RM De Tute, P Evans, D Ospina Cardona, ... Blood, The Journal of the American Society of Hematology 137 (26), 3676-3681, 2021 | 184 | 2021 |
Regulation of the CUL3 ubiquitin ligase by a calcium-dependent co-adaptor CA McGourty, D Akopian, C Walsh, A Gorur, A Werner, R Schekman, ... Cell 167 (2), 525-538. e14, 2016 | 135 | 2016 |
Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis MA Ferrada, S Savic, DO Cardona, JC Collins, H Alessi, ... Blood, The Journal of the American Society of Hematology 140 (13), 1496-1506, 2022 | 109 | 2022 |
Dimerization quality control ensures neuronal development and survival EL Mena, RAS Kjolby, RA Saxton, A Werner, BG Lew, JM Boyle, ... Science 362 (6411), eaap8236, 2018 | 82 | 2018 |
Disorders of ubiquitylation: unchained inflammation DB Beck, A Werner, DL Kastner, I Aksentijevich Nature Reviews Rheumatology 18 (8), 435-447, 2022 | 77 | 2022 |
Endosomal fusion upon SNARE knockdown is maintained by residual SNARE activity and enhanced docking I Bethani, A Werner, C Kadian, U Geumann, R Jahn, SO Rizzoli Traffic 10 (10), 1543-1559, 2009 | 59 | 2009 |
The Colossus of ubiquitylation: decrypting a cellular code A Williamson, A Werner, M Rape Molecular cell 49 (4), 591-600, 2013 | 56 | 2013 |
Ubiquitin-dependent regulation of stem cell biology A Werner, AG Manford, M Rape Trends in cell biology 27 (8), 568-579, 2017 | 49 | 2017 |
SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression A Werner, A Disanza, N Reifenberger, G Habeck, J Becker, M Calabrese, ... Nature cell biology 15 (2), 179-188, 2013 | 46 | 2013 |
Deubiquitylases in developmental ubiquitin signaling and congenital diseases MA Basar, DB Beck, A Werner Cell Death & Differentiation 28 (2), 538-556, 2021 | 39 | 2021 |
Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation DB Beck, MA Basar, AJ Asmar, JJ Thompson, H Oda, DT Uehara, K Saida, ... Science advances 7 (4), eabe2116, 2021 | 32 | 2021 |
Novel Somatic UBA1 Variant in a Patient With VEXAS Syndrome B Stiburkova, K Pavelcova, M Belickova, SJ Magaziner, JC Collins, ... Arthritis & Rheumatology 75 (7), 1285-1290, 2023 | 31 | 2023 |
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions A Werner, R Baur, N Teerikorpi, DU Kaya, M Rape Elife 7, e35407, 2018 | 27 | 2018 |
Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity HE Chatrathi, JC Collins, LA Wolfe, TC Markello, DR Adams, WA Gahl, ... Hypertension 79 (1), 60-75, 2022 | 22 | 2022 |
Myelodysplasia and bone marrow manifestations of somatic UBA1 mutated autoinflammatory disease IE Obiorah, DB Beck, W Wang, A Ombrello, MA Ferrada, Z Wu, KA Sikora, ... Blood 136, 20-21, 2020 | 22 | 2020 |
Nix interacts with WIPI2 to induce mitophagy EN Bunker, F Le Guerroué, C Wang, MP Strub, A Werner, N Tjandra, ... The EMBO journal 42 (22), e113491, 2023 | 21 | 2023 |
TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1 F Le Guerroué, EN Bunker, WM Rosencrans, JT Nguyen, MA Basar, ... Molecular cell 83 (6), 927-941. e8, 2023 | 19 | 2023 |