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Nicholas Z. Lue
Nicholas Z. Lue
Dirección de correo verificada de berkeley.edu
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Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders
PM Gosavi, KC Ngan, MJR Yeo, C Su, J Li, NZ Lue, SM Hoenig, BB Liau
ACS Central Science 8 (4), 417-429, 2022
462022
Base editor scanning charts the DNMT3A activity landscape
NZ Lue, EM Garcia, KC Ngan, C Lee, JG Doench, BB Liau
Nature Chemical Biology 19 (2), 176-186, 2023
362023
Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery
AP Siegenfeld, SA Roseman, H Roh, NZ Lue, CC Wagen, E Zhou, ...
Nature Communications 13 (1), 4199, 2022
252022
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery
KCH Ngan, SM Hoenig, HS Kwok, NZ Lue, PM Gosavi, DA Tanner, ...
Elife 12, e80640, 2023
162023
Base editor screens for in situ mutational scanning at scale
NZ Lue, BB Liau
Molecular Cell 83 (13), 2167-2187, 2023
152023
Base editor scanning reveals activating mutations of DNMT3A
EM Garcia, NZ Lue, JK Liang, WK Lieberman, DD Hwang, JC Woods, ...
ACS chemical biology 18 (9), 2030-2038, 2023
62023
CRISPR‐Suppressor scanning for systematic discovery of drug‐resistance mutations
KC Ngan, NZ Lue, C Lee, BB Liau
Current protocols 2 (12), e614, 2022
52022
DNA methylation insulates genic regions from CTCF loops near nuclear speckles
SA Roseman, AP Siegenfeld, C Lee, NZ Lue, AL Waterbury, BB Liau
bioRxiv, 2023.07. 26.550645, 2023
22023
Structural insights into transcriptional regulation by the helicase RECQL5
AJ Florez Ariza, NZ Lue, P Grob, B Kaeser, J Fang, SA Kassube, ...
bioRxiv, 2025.01. 29.634372, 2025
2025
Probing regulatory mechanisms of the de novo DNA methyltransferase DNMT3A
EM Garcia, NZ Lue, K Rivera, M Virshup, JK Liang, DD Hwang, SA Carr, ...
Biophysical Journal 122 (3), 352a, 2023
2023
Integrating functional genomics and biochemistry to interrogate DNMT3A sequence–function
NZB Lue
Harvard University, 2023
2023
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Artículos 1–11