| Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies Y Yamazaki, N Zhao, TR Caulfield, CC Liu, G Bu Nature Reviews Neurology 15 (9), 501-518, 2019 | 1157 | 2019 |
| Apolipoprotein E, receptors, and modulation of Alzheimer’s disease N Zhao, CC Liu, W Qiao, G Bu Biological psychiatry 83 (4), 347-357, 2018 | 390 | 2018 |
| ApoE4 accelerates early seeding of amyloid pathology CC Liu, N Zhao, Y Fu, N Wang, C Linares, CW Tsai, G Bu Neuron 96 (5), 1024-1032. e3, 2017 | 386 | 2017 |
| Apolipoprotein E4 impairs neuronal insulin signaling by trapping insulin receptor in the endosomes N Zhao, CC Liu, AJ Van Ingelgom, YA Martens, C Linares, JA Knight, ... Neuron 96 (1), 115-129. e5, 2017 | 288 | 2017 |
| Astrocytic LRP1 mediates brain Aβ clearance and impacts amyloid deposition CC Liu, J Hu, N Zhao, J Wang, N Wang, JR Cirrito, T Kanekiyo, ... Journal of Neuroscience 37 (15), 4023-4031, 2017 | 246 | 2017 |
| ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias YA Martens, N Zhao, CC Liu, T Kanekiyo, AJ Yang, AM Goate, ... Neuron 110 (8), 1304-1317, 2022 | 214 | 2022 |
| APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease Z Li, F Shue, N Zhao, M Shinohara, G Bu Molecular neurodegeneration 15 (1), 63, 2020 | 212 | 2020 |
| Alzheimer’s risk factors age, APOE genotype, and sex drive distinct molecular pathways N Zhao, Y Ren, Y Yamazaki, W Qiao, F Li, LM Felton, ... Neuron 106 (5), 727-742. e6, 2020 | 207 | 2020 |
| Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer’s disease CC Liu, N Zhao, Y Yamaguchi, JR Cirrito, T Kanekiyo, DM Holtzman, G Bu Science translational medicine 8 (332), 332ra44-332ra44, 2016 | 174 | 2016 |
| TDP-43 pathology in Alzheimer’s disease A Meneses, S Koga, J O’Leary, DW Dickson, G Bu, N Zhao Molecular neurodegeneration 16, 1-15, 2021 | 166 | 2021 |
| APOE ε2 is associated with increased tau pathology in primary tauopathy N Zhao, CC Liu, AJ Van Ingelgom, C Linares, A Kurti, JA Knight, ... Nature communications 9 (1), 4388, 2018 | 133 | 2018 |
| APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid N Zhao, ON Attrebi, Y Ren, W Qiao, B Sonustun, YA Martens, ... Science translational medicine 12 (529), eaay1809, 2020 | 130 | 2020 |
| Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage N Zhao, C Zhong, Y Wang, Y Zhao, N Gong, G Zhou, T Xu, Z Hong Neurobiology of disease 29 (2), 176-185, 2008 | 125 | 2008 |
| Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease M Shinohara, ME Murray, RD Frank, M Shinohara, M DeTure, Y Yamazaki, ... Acta neuropathologica 132, 225-234, 2016 | 114 | 2016 |
| Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function CC Liu, J Zhao, Y Fu, Y Inoue, Y Ren, Y Chen, SV Doss, F Shue, ... Nature neuroscience 25 (8), 1020-1033, 2022 | 109 | 2022 |
| TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration M Xie, YU Liu, S Zhao, L Zhang, DB Bosco, YP Pang, J Zhong, U Sheth, ... Nature neuroscience 25 (1), 26-38, 2022 | 93 | 2022 |
| APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia CC Liu, ME Murray, X Li, N Zhao, N Wang, MG Heckman, F Shue, ... Science translational medicine 13 (613), eabc9375, 2021 | 72 | 2021 |
| LRP1 is a neuronal receptor for α-synuclein uptake and spread K Chen, YA Martens, A Meneses, DH Ryu, W Lu, AC Raulin, F Li, J Zhao, ... Molecular neurodegeneration 17 (1), 57, 2022 | 67 | 2022 |
| Nigral iron deposition occurs across motor phenotypes of Parkinson’s disease L Jin, J Wang, H Jin, G Fei, Y Zhang, W Chen, L Zhao, N Zhao, X Sun, ... European Journal of Neurology 19 (7), 969-976, 2012 | 60 | 2012 |
| Serum microRNA-133b is associated with low ceruloplasmin levels in Parkinson's disease N Zhao, L Jin, G Fei, Z Zheng, C Zhong Parkinsonism & related disorders 20 (11), 1177-1180, 2014 | 56 | 2014 |