The blood-brain barrier: bottleneck in brain drug development WM Pardridge NeuroRx 2, 3-14, 2005 | 3287 | 2005 |
Drug transport across the blood–brain barrier WM Pardridge Journal of cerebral blood flow & metabolism 32 (11), 1959-1972, 2012 | 2082 | 2012 |
Blood–brain barrier delivery WM Pardridge Drug discovery today 12 (1-2), 54-61, 2007 | 1546 | 2007 |
Blood-brain barrier drug targeting: the future of brain drug development WM Pardridge Molecular interventions 3 (2), 90, 2003 | 1015 | 2003 |
Brain metabolism: a perspective from the blood-brain barrier WM Pardridge Physiological reviews 63 (4), 1481-1535, 1983 | 957 | 1983 |
Brain drug delivery of small molecules using immunoliposomes J Huwyler, D Wu, WM Pardridge Proceedings of the National Academy of Sciences 93 (24), 14164-14169, 1996 | 899 | 1996 |
Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization. WM Pardridge, RJ Boado, CR Farrell Journal of Biological Chemistry 265 (29), 18035-18040, 1990 | 776 | 1990 |
Drug and gene targeting to the brain with molecular Trojan horses WM Pardridge Nature reviews Drug discovery 1 (2), 131-139, 2002 | 673 | 2002 |
Delivery of peptides and proteins through the blood–brain barrier U Bickel, T Yoshikawa, WM Pardridge Advanced drug delivery reviews 46 (1-3), 247-279, 2001 | 667 | 2001 |
TRANSPORT OF METABOLIC SUBSTRATES THROUGH THE BLOOD‐BRAIN BARRIER1 WM Pardridge, WH Oldendorf Journal of neurochemistry 28 (1), 5-12, 1977 | 666 | 1977 |
CNS drug design based on principles of blood‐brain barrier transport WM Pardridge Journal of neurochemistry 70 (5), 1781-1792, 1998 | 655 | 1998 |
Blood-brain barrier biology and methodology WM Pardridge Journal of neurovirology 5 (6), 556-569, 1999 | 616 | 1999 |
Drug targeting to the brain WM Pardridge Pharmaceutical research 24, 1733-1744, 2007 | 611 | 2007 |
Strategies to advance translational research into brain barriers E Neuwelt, NJ Abbott, L Abrey, WA Banks, B Blakley, T Davis, ... The Lancet Neurology 7 (1), 84-96, 2008 | 568 | 2008 |
Selective expression of the large neutral amino acid transporter at the blood–brain barrier RJ Boado, JY Li, M Nagaya, C Zhang, WM Pardridge Proceedings of the National Academy of Sciences 96 (21), 12079-12084, 1999 | 567 | 1999 |
Transport of Protein-Bound Hormones into Tissues in Vivo WM Pardridge Endocrine reviews 2 (1), 103-123, 1981 | 562 | 1981 |
Capillary depletion method for quantification of blood–brain barrier transport of circulating peptides and plasma proteins D Triguero, J Buciak, WM Pardridge Journal of neurochemistry 54 (6), 1882-1888, 1990 | 561 | 1990 |
Transport of Steroid Hormones through the Rat Blood-Brain Barrier: PRIMARY ROLE OF ALBUMIN-BOUND HORMONE WM Pardridge, LJ Mietus The Journal of clinical investigation 64 (1), 145-154, 1979 | 537 | 1979 |
Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels. PL Golden, TJ Maccagnan, WM Pardridge The journal of clinical investigation 99 (1), 14-18, 1997 | 521 | 1997 |
Drug and gene delivery to the brain: the vascular route WM Pardridge Neuron 36 (4), 555-558, 2002 | 517 | 2002 |