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Se Hoon Choi
Se Hoon Choi
Assistant Professor of Neurology, Massachusetts General Hospital and Harvard Medical School
Dirección de correo verificada de mgh.harvard.edu
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A three-dimensional human neural cell culture model of Alzheimer’s disease
SH Choi, YH Kim, M Hebisch, C Sliwinski, S Lee, C D’Avanzo, H Chen, ...
Nature 515 (7526), 274-278, 2014
13262014
Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease
DKV Kumar, SH Choi, KJ Washicosky, WA Eimer, S Tucker, J Ghofrani, ...
Science translational medicine 8 (340), 340ra72-340ra72, 2016
11022016
Alzheimer’s disease risk gene CD33 inhibits microglial uptake of amyloid beta
A Griciuc, A Serrano-Pozo, AR Parrado, AN Lesinski, CN Asselin, K Mullin, ...
Neuron 78 (4), 631-643, 2013
10982013
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
SH Choi, E Bylykbashi, ZK Chatila, SW Lee, B Pulli, GD Clemenson, ...
Science 361 (6406), eaan8821, 2018
7442018
TREM2 acts downstream of CD33 in modulating microglial pathology in Alzheimer’s disease
A Griciuc, S Patel, AN Federico, SH Choi, BJ Innes, MK Oram, ...
Neuron 103 (5), 820-835. e7, 2019
3142019
A 3D human neural cell culture system for modeling Alzheimer's disease
YH Kim, SH Choi, C D'avanzo, M Hebisch, C Sliwinski, E Bylykbashi, ...
Nature protocols 10 (7), 985-1006, 2015
2782015
Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease
CS McAlpine, J Park, A Griciuc, E Kim, SH Choi, Y Iwamoto, MG Kiss, ...
Nature 595 (7869), 701-706, 2021
2572021
Exercise hormone irisin is a critical regulator of cognitive function
MR Islam, S Valaris, MF Young, EB Haley, R Luo, SF Bond, S Mazuera, ...
Nature Metabolism 3 (8), 1058-1070, 2021
2462021
ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function
J Suh, SH Choi, DM Romano, MA Gannon, AN Lesinski, DY Kim, ...
Neuron 80 (2), 385-401, 2013
2462013
Blood–brain barrier dysfunction in a 3D in vitro model of Alzheimer's disease
Y Shin, SH Choi, E Kim, E Bylykbashi, JA Kim, S Chung, DY Kim, ...
Advanced science 6 (20), 1900962, 2019
2402019
Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation
SH Choi, K Veeraraghavalu, O Lazarov, S Marler, RM Ransohoff, ...
Neuron 59 (4), 568-580, 2008
2232008
Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT‐11
CH Park, SH Choi, JW Koo, JH Seo, HS Kim, SJ Jeong, YH Suh
Journal of neuroscience research 70 (3), 484-492, 2002
1942002
Postnatal environment can counteract prenatal effects on cognitive ability, cell proliferation, and synaptic protein expression
JW Koo, CH Park, SH Choi, NJ Kim, HS Kim, JC Choe, YH Suh
The FASEB journal 17 (11), 1-27, 2003
1912003
Accelerated Aβ deposition in APPswe/PS1δE9 mice with hemizygous deletions of TTR (transthyretin)
SH Choi, SN Leight, VMY Lee, T Li, PC Wong, JA Johnson, MJ Saraiva, ...
Journal of Neuroscience 27 (26), 7006-7010, 2007
1792007
Amyloid β peptide induces cytochrome c release from isolated mitochondria
HS Kim, JH Lee, JP Lee, EM Kim, KA Chang, CH Park, SJ Jeong, ...
Neuroreport 13 (15), 1989-1993, 2002
1712002
3D culture models of Alzheimer’s disease: a road map to a “cure-in-a-dish”
SH Choi, YH Kim, L Quinti, RE Tanzi, DY Kim
Molecular neurodegeneration 11, 1-11, 2016
1472016
Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease
SS Kwak, KJ Washicosky, E Brand, D von Maydell, J Aronson, S Kim, ...
Nature communications 11 (1), 1377, 2020
1342020
Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF
SH Choi, Y Li, LF Parada, SS Sisodia
Molecular neurodegeneration 4, 1-12, 2009
1342009
Adult neurogenesis is functionally associated with AD-like neurodegeneration
Q Chen, A Nakajima, SH Choi, X Xiong, SS Sisodia, YP Tang
Neurobiology of disease 29 (2), 316-326, 2008
1302008
α‐Synuclein induces apoptosis by altered expression in human peripheral lymphocytes in Parkinson’s disease
S Kim, BS Jeon, C Heo, PS Im, TB Ahn, JH Seo, HS Kim, CH Park, ...
The FASEB journal 18 (13), 1615-1617, 2004
1262004
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