Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014 | 323 | 2014 |
Structure reveals mechanisms of viral suppressors that intercept a CRISPR RNA-guided surveillance complex S Chowdhury, J Carter, MCF Rollins, SM Golden, RN Jackson, ... Cell 169 (1), 47-57. e11, 2017 | 234 | 2017 |
The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis TM Walker, P Miotto, CU Köser, PW Fowler, J Knaggs, Z Iqbal, M Hunt, ... The Lancet Microbe 3 (4), e265-e273, 2022 | 193 | 2022 |
Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity MCF Rollins, S Chowdhury, J Carter, SM Golden, RA Wilkinson, ... Proceedings of the National Academy of Sciences 114 (26), E5113-E5121, 2017 | 104 | 2017 |
Structure reveals a mechanism of CRISPR-RNA-guided nuclease recruitment and anti-CRISPR viral mimicry MCF Rollins, S Chowdhury, J Carter, SM Golden, HM Miettinen, ... Molecular cell 74 (1), 132-142. e5, 2019 | 100 | 2019 |
Fitting CRISPR-associated Cas3 into the helicase family tree RN Jackson, M Lavin, J Carter, B Wiedenheft Current opinion in structural biology 24, 106-114, 2014 | 97 | 2014 |
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics CRyPTIC Consortium PLoS biology 20 (8), e3001721, 2022 | 72 | 2022 |
Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli PBG Van Erp, RN Jackson, J Carter, SM Golden, S Bailey, B Wiedenheft Nucleic acids research 43 (17), 8381-8391, 2015 | 66 | 2015 |
Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis CRyPTIC Consortium European Respiratory Journal 60 (4), 2022 | 59 | 2022 |
SnapShot: CRISPR-RNA-guided adaptive immune systems J Carter, B Wiedenheft Cell 163 (1), 260-260. e1, 2015 | 39 | 2015 |
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis L Sonnenkalb, JJ Carter, A Spitaleri, Z Iqbal, M Hunt, KM Malone, ... The Lancet Microbe 4 (5), e358-e368, 2023 | 37 | 2023 |
Conformational dynamics of DNA binding and Cas3 recruitment by the CRISPR RNA-guided cascade complex PBG van Erp, A Patterson, R Kant, L Berry, SM Golden, BL Forsman, ... ACS chemical biology 13 (2), 481-490, 2018 | 35 | 2018 |
Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene … CRyPTIC Consortium, JJ Carter bioRxiv, 2021.09. 14.460353, 2021 | 32* | 2021 |
Deciphering bedaquiline and clofazimine resistance in tuberculosis: an evolutionary medicine approach L Sonnenkalb, J Carter, A Spitaleri, Z Iqbal, M Hunt, K Malone, C Utpatel, ... Biorxiv, 2021.03. 19.436148, 2021 | 21 | 2021 |
A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth … PW Fowler, C Wright, H Spiers, T Zhu, EML Baeten, SW Hoosdally, ... Elife 11, e75046, 2022 | 18 | 2022 |
Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine-learning approaches JJ Carter, TM Walker, AS Walker, MG Whitfield, GP Morlock, CI Lynch, ... JAC-Antimicrobial Resistance 6 (2), dlae037, 2024 | 16 | 2024 |
The interfaces of genetic conflict are hot spots for innovation J Carter, C Hoffman, B Wiedenheft Cell 168 (1), 9-11, 2017 | 13 | 2017 |
Vaccine design via antigen reorientation D Xu, JJ Carter, C Li, A Utz, PAB Weidenbacher, S Tang, M Sanyal, ... Nature Chemical Biology, 1-10, 2024 | 10 | 2024 |
A data compendium of Mycobacterium tuberculosis antibiotic resistance A Brankin, KM Malone, I Barilar, S Battaglia, E Borroni, AP Brandao, ... Biorxiv, 2021.09. 14.460274, 2021 | 8 | 2021 |
Sustained vaccine exposure elicits more rapid, consistent, and broad humoral immune responses to multivalent influenza vaccines OM Saouaf, BS Ou, YE Song, JJ Carter, J Yan, CK Jons, CO Barnes, ... bioRxiv, 2024.04. 28.591370, 2024 | | 2024 |