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Joel Federspiel
Joel Federspiel
Sr. Principal Scientist, Pfizer
Dirección de correo verificada de pfizer.com
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Año
Proteomics and integrative omic approaches for understanding host–pathogen interactions and infectious diseases
PM Jean Beltran, JD Federspiel, X Sheng, IM Cristea
Molecular systems biology 13 (3), 922, 2017
2142017
Sorafenib Is an Inhibitor of UGT1A1 but Is Metabolized by UGT1A9: Implications of Genetic Variants on Pharmacokinetics and HyperbilirubinemiaUGT1A Variants Affect Sorafenib …
CJ Peer, TM Sissung, AR Kim, L Jain, S Woo, ER Gardner, CT Kirkland, ...
Clinical cancer research 18 (7), 2099-2107, 2012
1352012
Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription
S Gilbertson, JD Federspiel, E Hartenian, IM Cristea, B Glaunsinger
elife 7, e37663, 2018
1112018
Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation
W Shi, X Sheng, KM Dorr, JE Hutton, JI Emerson, HA Davies, TD Andrade, ...
Developmental cell 56 (21), 3019-3034. e7, 2021
652021
Interactome and proteome dynamics uncover immune modulatory associations of the pathogen sensing factor cGAS
KK Lum, B Song, JD Federspiel, BA Diner, T Howard, IM Cristea
Cell systems 7 (6), 627-642. e6, 2018
412018
Hdac4 interactions in Huntington's Disease viewed through the prism of multiomics
JD Federspiel, TM Greco, KK Lum, IM Cristea
Molecular & Cellular Proteomics 18 (8), S92-S113, 2019
392019
Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein
BN Lizama, AM Palubinsky, VA Raveendran, AM Moore, JD Federspiel, ...
Journal of Neuroscience 38 (31), 6825-6840, 2018
352018
Assembly dynamics and stoichiometry of the apoptosis signal-regulating kinase (ASK) signalosome in response to electrophile stress
JD Federspiel, SG Codreanu, AM Palubinsky, AJ Winland, CM Betanzos, ...
Molecular & Cellular Proteomics 15 (6), 1947-1961, 2016
352016
Specificity of protein covalent modification by the electrophilic proteasome inhibitor carfilzomib in human cells
JD Federspiel, SG Codreanu, S Goyal, ME Albertolle, E Lowe, J Teague, ...
Molecular & Cellular Proteomics 15 (10), 3233-3242, 2016
292016
Mechanical Force Induces Phosphorylation-Mediated Signaling that Underlies Tissue Response and Robustness in Xenopus Embryos
Y Hashimoto, N Kinoshita, TM Greco, JD Federspiel, PMJ Beltran, N Ueno, ...
Cell systems 8 (3), 226-241. e7, 2019
282019
Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA
JD Federspiel, KC Cook, MA Kennedy, SS Venkatesh, CJ Otter, ...
Cell Reports 32 (4), 107943, 2020
272020
The human cytomegalovirus protein pUL13 targets mitochondrial cristae architecture to increase cellular respiration during infection
CN Betsinger, CSR Jankowski, WA Hofstadter, JD Federspiel, CJ Otter, ...
Proceedings of the National Academy of Sciences 118 (32), e2101675118, 2021
262021
Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans
KC Ravindra, VS Vaidya, Z Wang, JD Federspiel, R Virgen-Slane, ...
Nature communications 14 (1), 1215, 2023
232023
Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease
TM Greco, C Secker, ES Ramos, JD Federspiel, JP Liu, AM Perez, ...
Cell Systems 13 (4), 304-320. e5, 2022
212022
RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters
E Hartenian, S Gilbertson, JD Federspiel, IM Cristea, BA Glaunsinger
PLoS pathogens 16 (2), e1008269, 2020
212020
Conservation and divergence of protein pathways in the vertebrate heart
JD Federspiel, P Tandon, CM Wilczewski, L Wasson, LE Herring, ...
PLoS biology 17 (9), e3000437, 2019
192019
Complement Activation by Adeno-Associated Virus-Neutralizing Antibody Complexes
C West, JD Federspiel, K Rogers, A Khatri, S Rao-Dayton, MF Ocana, ...
Human Gene Therapy 34 (11-12), 554-566, 2023
182023
Dynamic phosphorylation of apoptosis signal regulating kinase 1 (ASK1) in response to oxidative and electrophilic stress
C Morales Betanzos, JD Federspiel, AM Palubinsky, BA McLaughlin, ...
Chemical Research in Toxicology 29 (12), 2175-2183, 2016
142016
Considerations for identifying endogenous protein complexes from tissue via immunoaffinity purification and quantitative mass spectrometry
JD Federspiel, IM Cristea
Mass Spectrometry of Proteins, 115-143, 2019
112019
A TRUSTED targeted mass spectrometry assay for pan-herpesvirus protein detection
MA Kennedy, MD Tyl, CN Betsinger, JD Federspiel, X Sheng, JH Arbuckle, ...
Cell reports 39 (6), 2022
92022
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