Non-canonical hedgehog signaling pathway in cancer: activation of GLI transcription factors beyond smoothened S Pietrobono, S Gagliardi, B Stecca Frontiers in genetics 10, 556, 2019 | 321 | 2019 |
SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells R Santini, S Pietrobono, S Pandolfi, V Montagnani, M D'Amico, ... Oncogene 33 (38), 4697-4708, 2014 | 243 | 2014 |
Aberrant sialylation in cancer: biomarker and potential target for therapeutic intervention? S Pietrobono, B Stecca Cancers 13 (9), 2014, 2021 | 95 | 2021 |
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL S Pietrobono, G Anichini, C Sala, F Manetti, LL Almada, S Pepe, RM Carr, ... Nature communications 11 (1), 5865, 2020 | 69 | 2020 |
Soft tissue sarcoma cancer stem cells: an overview KC Genadry, S Pietrobono, R Rota, CM Linardic Frontiers in oncology 8, 475, 2018 | 61 | 2018 |
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe S Pietrobono, R Santini, S Gagliardi, F Dapporto, D Colecchia, ... Cell Death & Disease 9 (2), 142, 2018 | 49 | 2018 |
Targeting the oncoprotein smoothened by small molecules: focus on novel acylguanidine derivatives as potent smoothened inhibitors S Pietrobono, B Stecca Cells 7 (12), 272, 2018 | 46 | 2018 |
Down-regulation of SOX2 underlies the inhibitory effects of the triphenylmethane gentian violet on melanoma cell self-renewal and survival S Pietrobono, A Morandi, S Gagliardi, G Gerlini, L Borgognoni, P Chiarugi, ... Journal of Investigative Dermatology 136 (10), 2059-2069, 2016 | 39 | 2016 |
Perioperative NALIRIFOX in patients with resectable pancreatic ductal adenocarcinoma: The open-label, multicenter, phase II nITRO trial D Melisi, C Zecchetto, V Merz, G Malleo, L Landoni, A Quinzii, S Casalino, ... European Journal of Cancer 196, 113430, 2024 | 36 | 2024 |
SOX2 as a novel contributor of oxidative metabolism in melanoma cells E Andreucci, S Pietrobono, S Peppicelli, J Ruzzolini, F Bianchini, ... Cell Communication and Signaling 16, 1-13, 2018 | 36 | 2018 |
The role of glycosylation in melanoma progression C De Vellis, S Pietrobono, B Stecca Cells 10 (8), 2136, 2021 | 35 | 2021 |
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma S Pietrobono, E Gaudio, S Gagliardi, M Zitani, L Carrassa, F Migliorini, ... Oncogene 40 (22), 3799-3814, 2021 | 35 | 2021 |
The multifaceted role of TGF-β in gastrointestinal tumors F Sabbadini, M Bertolini, S De Matteis, D Mangiameli, S Contarelli, ... Cancers 13 (16), 3960, 2021 | 33 | 2021 |
Autotaxin secretion is a stromal mechanism of adaptive resistance to TGFβ inhibition in pancreatic ductal adenocarcinoma S Pietrobono, F Sabbadini, M Bertolini, D Mangiameli, V De Vita, ... Cancer Research 84 (1), 118-132, 2024 | 12 | 2024 |
Exceptional clinical response to alectinib in pancreatic acinar cell carcinoma with a novel ALK-KANK4 gene fusion M Gaule, C Pesoni, A Quinzii, C Zecchetto, S Casalino, V Merz, ... JCO Precision Oncology 6, 2022 | 12 | 2022 |
MAPK15 controls hedgehog signaling in medulloblastoma cells by regulating primary ciliogenesis S Pietrobono, L Franci, F Imperatore, C Zanini, B Stecca, M Chiariello Cancers 13 (19), 4903, 2021 | 9 | 2021 |
Predictive biomarkers for a personalized approach in resectable pancreatic cancer V Merz, D Mangiameli, C Zecchetto, A Quinzii, S Pietrobono, C Messina, ... Frontiers in Surgery 9, 866173, 2022 | 8 | 2022 |
Clinical response to futibatinib in patients with high-level FGFR2-amplified advanced gastric cancer: two case reports A Quinzii, C Zecchetto, S Casalino, M Gaule, C Pesoni, V Merz, ... Clinical Drug Investigation 42 (8), 697-701, 2022 | 5 | 2022 |
Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells C Sala, G Mattiuz, S Pietrobono, A Chicca, SG Conticello Plos one 10 (3), e0121719, 2015 | 4 | 2015 |
Regulation of melanoma initiating cells by Hedgehog signaling and SOX2 R Santini, S Pandolfi, V Montagnani, S Pietrobono, N Pimpinelli, ... Journal of Translational Medicine 12, 1-2, 2014 | 4 | 2014 |