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ajay ashok
ajay ashok
Research Fellow, Schepens Eye Research Institute, Mass Eye and Ear
Dirección de correo verificada de meei.harvard.edu
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Retinal degeneration and Alzheimer’s disease: an evolving link
A Ashok, N Singh, S Chaudhary, V Bellamkonda, AE Kritikos, AS Wise, ...
International journal of molecular sciences 21 (19), 7290, 2020
1262020
Prion protein modulates glucose homeostasis by altering intracellular iron
A Ashok, N Singh
Scientific reports 8 (1), 6556, 2018
442018
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium
JR Soucy, EA Aguzzi, J Cho, MJ Gilhooley, C Keuthan, Z Luo, ...
Molecular neurodegeneration 18 (1), 64, 2023
252023
Integrated 3D printed scaffolds and electrical stimulation for enhancing primary human cardiomyocyte cultures
SD Adams, A Ashok, RK Kanwar, JR Kanwar, AZ Kouzani
Bioprinting 6, 18-24, 2017
242017
Prion protein modulates endothelial to mesenchyme-like transition in trabecular meshwork cells: Implications for primary open angle glaucoma
A Ashok, MH Kang, AS Wise, P Pattabiraman, WM Johnson, M Lonigro, ...
Scientific reports 9 (1), 13090, 2019
222019
Transport of non-transferrin bound iron to the brain: implications for Alzheimer’s disease
AK Tripathi, S Karmakar, A Asthana, A Ashok, V Desai, S Baksi, N Singh
Journal of Alzheimer's Disease 58 (4), 1109-1119, 2017
202017
Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders
A Asthana, S Baksi, A Ashok, S Karmakar, N Mammadova, R Kokemuller, ...
Scientific reports 7 (1), 9600, 2017
192017
Prion protein modulates iron transport in the anterior segment: Implications for ocular iron homeostasis and prion transmission
A Ashok, S Karmakar, R Chandel, R Ravikumar, S Dalal, Q Kong, N Singh
Experimental eye research 175, 1-13, 2018
182018
Upregulation of local hepcidin contributes to iron accumulation in Alzheimer’s disease brains
S Chaudhary, A Ashok, D McDonald, AS Wise, AE Kritikos, NA Rana, ...
Journal of Alzheimer's Disease 82 (4), 1487-1497, 2021
162021
TGFβ2-hepcidin feed-forward loop in the trabecular meshwork implicates iron in glaucomatous pathology
A Ashok, S Chaudhary, AE Kritikos, MH Kang, D McDonald, DJ Rhee, ...
Investigative Ophthalmology & Visual Science 61 (3), 24-24, 2020
152020
Direct modulation of microglial function by electrical field
A Lennikov, M Yang, K Chang, L Pan, MS Saddala, C Lee, A Ashok, ...
Frontiers in Cell and Developmental Biology 10, 980775, 2022
142022
Local synthesis of hepcidin in the anterior segment of the eye: A novel observation with physiological and pathological implications
A Ashok, S Chaudhary, D McDonald, A Kritikos, D Bhargava, N Singh
Experimental eye research 190, 107890, 2020
142020
Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface
M Yang, A Lennikov, K Chang, A Ashok, C Lee, KS Cho, TP Utheim, ...
BMC ophthalmology 22 (1), 490, 2022
92022
Epigenetic regulation of optic nerve development, protection, and repair
A Ashok, S Pooranawattanakul, WL Tai, KS Cho, TP Utheim, DM Cestari, ...
International Journal of Molecular Sciences 23 (16), 8927, 2022
82022
Prions and prion diseases: insights from the eye
N Singh, S Chaudhary, A Ashok, E Lindner
Experimental eye research 199, 108200, 2020
82020
Release of iron-loaded ferritin in sodium iodate-induced model of age related macular degeneration: an in-vitro and in-vivo study
A Ashok, S Chaudhary, AS Wise, NA Rana, D McDonald, AE Kritikos, ...
Antioxidants 10 (08), 1253, 2021
72021
SurR9C84A protects and recovers human cardiomyocytes from hypoxia induced apoptosis
A Ashok, JR Kanwar, UM Krishnan, RK Kanwar
Experimental Cell Research 350 (1), 19-31, 2017
72017
Electrical stimulation alters DNA methylation and promotes neurite outgrowth
A Ashok, WL Tai, A Lennikov, K Chang, J Chen, B Li, KS Cho, TP Utheim, ...
Journal of Cellular Biochemistry, 2023
62023
Suppressing DNMT3a Alleviates the Intrinsic Epigenetic Barrier for Optic Nerve Regeneration and Restores Vision in Adult Mice
WL Tai, KS Cho, E Kriukov, A Ashok, X Wang, A Monavarfeshani, W Yan, ...
bioRxiv, 2023
32023
Epigenetic modulation following electrical stimulation in neurons
A Ashok, WL Tai, A Lennikov, KS Cho, T Utheim, D Chen
Investigative Ophthalmology & Visual Science 63 (7), 2969–F0210-2969–F0210, 2022
32022
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