Empagliflozin directly improves diastolic function in human heart failure S Pabel, S Wagner, H Bollenberg, P Bengel, A Kovacs, C Schach, ... European journal of heart failure 20 (12), 1690-1700, 2018 | 233 | 2018 |
Empagliflozin reduces Ca/calmodulin‐dependent kinase II activity in isolated ventricular cardiomyocytes J Mustroph, O Wagemann, CM Lücht, M Trum, KP Hammer, CM Sag, ... ESC heart failure 5 (4), 642-648, 2018 | 200 | 2018 |
CaMKII as a target for arrhythmia suppression J Mustroph, S Neef, LS Maier Pharmacology & therapeutics 176, 22-31, 2017 | 105 | 2017 |
Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor S Neef, A Steffens, P Pellicena, J Mustroph, S Lebek, KR Ort, H Schulman, ... Journal of molecular and cellular cardiology 115, 73-81, 2018 | 84 | 2018 |
The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity S Lebek, A Plößl, M Baier, J Mustroph, D Tarnowski, CM Lücht, ... Journal of molecular and cellular cardiology 118, 159-168, 2018 | 67 | 2018 |
Enhanced CaMKII-Dependent Late INa Induces Atrial Proarrhythmic Activity in Patients With Sleep-Disordered Breathing S Lebek, K Pichler, K Reuthner, M Trum, M Tafelmeier, J Mustroph, ... Circulation Research 126 (5), 603-615, 2020 | 65 | 2020 |
CaMKII regulation of cardiac K channels J Mustroph, LS Maier, S Wagner Frontiers in pharmacology 5, 20, 2014 | 48 | 2014 |
SR Ca2+-leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure J Mustroph, O Wagemann, S Lebek, D Tarnowski, J Ackermann, ... Journal of molecular and cellular cardiology 116, 81-90, 2018 | 42 | 2018 |
Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice S Pabel, S Ahmad, P Tirilomis, T Stehle, J Mustroph, M Knierim, ... Basic Research in Cardiology 115, 1-14, 2020 | 36 | 2020 |
Empagliflozin enhances human and murine cardiomyocyte glucose uptake by increased expression of GLUT1 J Mustroph, CM Lücht, O Wagemann, T Sowa, KP Hammer, CM Sag, ... Diabetologia 62, 726-729, 2019 | 34 | 2019 |
Mechanisms of cardiac ethanol toxicity and novel treatment options J Mustroph, S Lebek, LS Maier, S Neef Pharmacology & Therapeutics 197, 1-10, 2019 | 33 | 2019 |
Empagliflozin inhibits cardiac late sodium current by Ca/calmodulin-dependent kinase II J Mustroph, MJ Baier, S Pabel, T Stehle, M Trum, Z Provaznik, PJ Mohler, ... Circulation 146 (16), 1259-1261, 2022 | 32 | 2022 |
Kidney injury molecule-1: potential biomarker of acute kidney injury and disease severity in patients with COVID-19 MJ Vogel, J Mustroph, ST Staudner, SB Leininger, U Hubauer, S Wallner, ... Journal of nephrology 34 (4), 1007-1018, 2021 | 30 | 2021 |
RNA-expression of adrenomedullin is increased in patients with severe COVID-19 J Hupf, J Mustroph, F Hanses, K Evert, LS Maier, CG Jungbauer Critical Care 24, 1-3, 2020 | 30 | 2020 |
CaMKII and GLUT1 in heart failure and the role of gliflozins M Trum, S Wagner, LS Maier, J Mustroph Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (6), 165729, 2020 | 29 | 2020 |
The oral Ca/calmodulin‐dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure J Mustroph, M Drzymalski, M Baier, S Pabel, A Biedermann, B Memmel, ... ESC heart failure 7 (5), 2871-2883, 2020 | 26 | 2020 |
Long-term effects of empagliflozin on excitation-contraction-coupling in human induced pluripotent stem cell cardiomyocytes S Pabel, F Reetz, N Dybkova, O Shomroni, G Salinas, J Mustroph, ... Journal of Molecular Medicine 98, 1689-1700, 2020 | 24 | 2020 |
SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress M Tangos, H Budde, D Kolijn, M Sieme, S Zhazykbayeva, M Lódi, ... International Journal of Cardiology 362, 196-205, 2022 | 21 | 2022 |
Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure P Bengel, N Dybkova, P Tirilomis, S Ahmad, N Hartmann, B A. Mohamed, ... Nature Communications 12 (1), 6586, 2021 | 21 | 2021 |
Loss of CASK accelerates heart failure development J Mustroph, CM Sag, F Bähr, AL Schmidtmann, SN Gupta, A Dietz, ... Circulation research 128 (8), 1139-1155, 2021 | 21 | 2021 |