Comprehensive functional genomic resource and integrative model for the human brain D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ... Science 362 (6420), eaat8464, 2018 | 937 | 2018 |
Efficient and precise single-cell reference atlas mapping with Symphony JB Kang, A Nathan, K Weinand, F Zhang, N Millard, L Rumker, DB Moody, ... Nature communications 12 (1), 5890, 2021 | 169 | 2021 |
Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions M Gutierrez-Arcelus, N Teslovich, AR Mola, RB Polidoro, A Nathan, H Kim, ... Nature communications 10 (1), 687, 2019 | 164 | 2019 |
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation F Zhang, JR Mears, L Shakib, JI Beynor, S Shanaj, I Korsunsky, A Nathan, ... Genome medicine 13, 1-17, 2021 | 163 | 2021 |
Single-cell eQTL models reveal dynamic T cell state dependence of disease loci A Nathan, S Asgari, K Ishigaki, C Valencia, T Amariuta, Y Luo, JI Beynor, ... Nature 606 (7912), 120-128, 2022 | 130 | 2022 |
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes F Zhang, AH Jonsson, A Nathan, N Millard, M Curtis, Q Xiao, ... Nature 623 (7987), 616-624, 2023 | 120 | 2023 |
Presto scales Wilcoxon and auROC analyses to millions of observations I Korsunsky, A Nathan, N Millard, S Raychaudhuri BioRxiv, 653253, 2019 | 98 | 2019 |
Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease A Nathan, JI Beynor, Y Baglaenko, S Suliman, K Ishigaki, S Asgari, ... Nature Immunology 22 (6), 781-793, 2021 | 76 | 2021 |
Single-cell genomics meets human genetics ASE Cuomo, A Nathan, S Raychaudhuri, DG MacArthur, JE Powell Nature Reviews Genetics 24 (8), 535-549, 2023 | 71 | 2023 |
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain R Pourhaghighi, PEA Ash, S Phanse, F Goebels, LZM Hu, S Chen, ... Cell systems 10 (4), 333-350. e14, 2020 | 70 | 2020 |
Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate KA Lagattuta, JB Kang, A Nathan, KE Pauken, AH Jonsson, DA Rao, ... Nature Immunology 23 (3), 446-457, 2022 | 60 | 2022 |
Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics YA Reshef, L Rumker, JB Kang, A Nathan, I Korsunsky, S Asgari, ... Nature Biotechnology 40 (3), 355-363, 2022 | 55 | 2022 |
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation F Zhang, JR Mears, L Shakib, JI Beynor, S Shanaj, I Korsunsky, A Nathan, ... BioRxiv, 2020 | 40 | 2020 |
Design of Protein–Peptide Interaction Modules for Assembling Supramolecular Structures in Vivo and in Vitro EB Speltz, A Nathan, L Regan ACS chemical biology 10 (9), 2108-2115, 2015 | 38 | 2015 |
Associations between neighborhood‐level factors and opioid‐related mortality: A multi‐level analysis using death certificate data MW Flores, B Lê Cook, B Mullin, G Halperin‐Goldstein, A Nathan, ... Addiction 115 (10), 1878-1889, 2020 | 37 | 2020 |
Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritis F Zhang, AH Jonsson, A Nathan, K Wei, N Millard, Q Xiao, ... BioRxiv, 2022.02. 25.481990, 2022 | 36 | 2022 |
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders N Akula, S Marenco, K Johnson, N Feng, K Zhu, A Schulmann, W Corona, ... Neuropsychopharmacology 46 (7), 1364-1372, 2021 | 31 | 2021 |
High-dimensional phenotyping to define the genetic basis of cellular morphology M Tegtmeyer, J Arora, S Asgari, BA Cimini, A Nadig, E Peirent, ... Nature Communications 15 (1), 347, 2024 | 26 | 2024 |
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution JB Kang, AZ Shen, S Gurajala, A Nathan, L Rumker, VRC Aguiar, ... Nature genetics 55 (12), 2255-2268, 2023 | 24 | 2023 |
Methods and insights from single-cell expression quantitative trait loci JB Kang, A Raveane, A Nathan, N Soranzo, S Raychaudhuri Annual review of genomics and human genetics 24 (1), 277-303, 2023 | 23 | 2023 |