Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi Nature structural & molecular biology 26 (7), 637-648, 2019 | 595 | 2019 |
SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi The EMBO journal 39 (24), e106478, 2020 | 266 | 2020 |
The (un) structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy AC Murthy, NL Fawzi Journal of Biological Chemistry 295 (8), 2375-2384, 2020 | 112 | 2020 |
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ... | 101 | 2019 |
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads AC Murthy, WS Tang, N Jovic, AM Janke, DH Seo, TM Perdikari, J Mittal, ... Nature structural & molecular biology 28 (11), 923-935, 2021 | 91 | 2021 |
SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins. TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi BioRxiv, 2020 | 55 | 2020 |
N‐terminal acetylation modestly enhances phase separation and reduces aggregation of the low‐complexity domain of RNA‐binding protein fused in sarcoma AS Bock, AC Murthy, WS Tang, N Jovic, F Shewmaker, J Mittal, NL Fawzi Protein Science 30 (7), 1337-1349, 2021 | 39 | 2021 |
Reversible kinetic trapping of FUS biomolecular condensates S Chatterjee, Y Kan, M Brzezinski, K Koynov, RM Regy, AC Murthy, ... Advanced Science 9 (4), 2104247, 2022 | 37 | 2022 |
Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions D Maltseva, S Chatterjee, CC Yu, M Brzezinski, Y Nagata, G Gonella, ... Nature chemistry 15 (8), 1146-1154, 2023 | 23 | 2023 |
Incorporating NOE-derived distances in conformer generation of cyclic peptides with distance geometry S Wang, K Krummenacher, GA Landrum, BD Sellers, P Di Lello, ... Journal of Chemical Information and Modeling 62 (3), 472-485, 2022 | 15 | 2022 |
Molecular insights into the effect of alkanediols on FUS liquid-liquid phase separation TM Perdikari, A Murthy, NL Fawzi Biophysical Journal 122 (3), 484a, 2023 | 8 | 2023 |
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease. bioRxiv. 2019; 721001 RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ... Academic Search][CrossRef][Green Version], 0 | 8 | |
An inquiry-based laboratory module to promote understanding of the scientific method and bacterial conjugation MB Berkmen, AC Murthy, MP Broulidakis Journal of Microbiology & Biology Education 15 (2), 321-322, 2014 | 6 | 2014 |
Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models H Uechi, S Sridharan, J Nijssen, J Bilstein, JM Iglesias-Artola, S Kishigami, ... bioRxiv, 721001, 2019 | 4 | 2019 |
Small molecules for modulating protein driven liquid-liquid phase separation in neurodegenerative disease. RJ Wheeler, H Lee, A Pal, A Murthy, I Poser, L Marrone, T Doeleman, ... Molecular Biology of the Cell 28, 2017 | 4 | 2017 |
Interactions between FUS and the C-terminal domain of Nup62 are sufficient for their co-phase separation into amorphous assemblies MS Kumar, KM Stallworth, AC Murthy, SM Lim, N Li, A Jain, JB Munro, ... Journal of molecular biology 435 (6), 167972, 2023 | 3 | 2023 |
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains L Guo, JR Mann, JC Mauna, KE Copley, H Wang, JD Rubien, HM Odeh, ... bioRxiv, 2023.09. 04.555754, 2023 | 3 | 2023 |
EGFP insertional mutagenesis reveals multiple FXR2P fibrillar states with differing ribosome association in neurons EE Stackpole, MR Akins, M Ivshina, AC Murthy, NL Fawzi, JR Fallon Biology open 8 (8), bio046383, 2019 | 2 | 2019 |
Sapun H Parekh, Jeetain Mittal, and Nicolas L Fawzi. Molecular 35 interactions underlying liquid-liquid phase separation of the FUS low-36 complexity domain AC Murthy, GL Dignon, Y Kan, GH Zerze Nature Structural & Molecular Biology 26 (7), 637-37, 34 | 2 | 34 |
Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in Xenopus oocytes LC O’Connell, V Johnson, JP Otis, AK Hutton, AC Murthy, MC Liang, ... Scientific Reports 14 (1), 27890, 2024 | | 2024 |