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Jan Hoeijmakers
Jan Hoeijmakers
Prof. Molecular Genetics, Dept. Molec. Genetics, Erasmus University Medical Center, Rotterdam and
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Genome maintenance mechanisms for preventing cancer
JHJ Hoeijmakers
nature 411 (6835), 366-374, 2001
54322001
DNA damage, aging, and cancer
JHJ Hoeijmakers
New England journal of medicine 361 (15), 1475-1485, 2009
30552009
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA
M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ...
Developmental cell 31 (6), 722-733, 2014
19992014
Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
GTJ Horst, M Muijtjens, K Kobayashi, R Takano, S Kanno, M Takao, J Wit, ...
Nature 398 (6728), 627-630, 1999
17221999
Chromosomal stability and the DNA double-stranded break connection
DC Van Gent, JHJ Hoeijmakers, R Kanaar
Nature reviews genetics 2 (3), 196-206, 2001
16422001
Molecular mechanism of nucleotide excision repair
WL de Laat, NGJ Jaspers, JHJ Hoeijmakers
Genes & development 13 (7), 768-785, 1999
14891999
Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging
MP Baar, RMC Brandt, DA Putavet, JDD Klein, KWJ Derks, ...
Cell 169 (1), 132-147. e16, 2017
13812017
Understanding nucleotide excision repair and its roles in cancer and ageing
JA Marteijn, H Lans, W Vermeulen, JHJ Hoeijmakers
Nature reviews Molecular cell biology 15 (7), 465-481, 2014
13812014
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
DJ Rossi, D Bryder, J Seita, A Nussenzweig, J Hoeijmakers, IL Weissman
Nature 447 (7145), 725-729, 2007
13252007
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair
K Sugasawa, JMY Ng, C Masutani, S Iwai, PJ van der Spek, APM Eker, ...
Molecular cell 2 (2), 223-232, 1998
11711998
Sequential assembly of the nucleotide excision repair factors in vivo
M Volker, MJ Moné, P Karmakar, A van Hoffen, W Schul, W Vermeulen, ...
Molecular cell 8 (1), 213-224, 2001
10152001
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor
L Schaeffer, R Roy, S Humbert, V Moncollin, W Vermeulen, ...
Science 260 (5104), 58-63, 1993
10031993
Nucleotide excision repair and human syndromes
J De Boer, JHJ Hoeijmakers
Carcinogenesis 21 (3), 453-460, 2000
9592000
Cellular senescence drives age-dependent hepatic steatosis
M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ...
Nature communications 8 (1), 15691, 2017
9162017
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
C Troelstra, A van Gool, J de Wit, W Vermeulen, D Bootsma, ...
Cell 71 (6), 939-953, 1992
8651992
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
LJ Niedernhofer, GA Garinis, A Raams, AS Lalai, AR Robinson, ...
Nature 444 (7122), 1038-1043, 2006
7732006
Molecular mechanisms of DNA double-strand break repair
R Kanaar, JHJ Hoeijmakers, DC van Gent
Trends in cell biology 8 (12), 483-489, 1998
7461998
P53 MODULATION OF TFIIH-ASSOCIATED NUCLEOTIDE EXCISION-REPAIR ACTIVITY
XW WANG, H YEH, L SCHAEFFER, R ROY, V MONCOLLIN, JM EGLY, ...
Nature Genetics 10, 188-195, 1995
7281995
Aging and genome maintenance: lessons from the mouse?
P Hasty, J Campisi, J Hoeijmakers, H Van Steeg, J Vijg
Science 299 (5611), 1355-1359, 2003
6962003
Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease
AM Sijbers, WL De Laat, RR Ariza, M Biggerstaff, YF Wei, JG Moggs, ...
Cell 86 (5), 811-822, 1996
6881996
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Artículos 1–20