| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13792* | 2021 |
| Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation XC Dong, KD Copps, S Guo, Y Li, R Kollipara, RA DePinho, MF White Cell metabolism 8 (1), 65-76, 2008 | 542 | 2008 |
| Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice CW Lin, H Zhang, M Li, X Xiong, X Chen, X Chen, XC Dong, XM Yin Journal of hepatology 58 (5), 993-999, 2013 | 447 | 2013 |
| The autophagy-related gene 14 (Atg14) is regulated by forkhead box O transcription factors and circadian rhythms and plays a critical role in hepatic autophagy and lipid metabolism X Xiong, R Tao, RA DePinho, XC Dong Journal of Biological Chemistry 287 (46), 39107-39114, 2012 | 234 | 2012 |
| FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 … R Tao, X Xiong, RA DePinho, CX Deng, XC Dong Journal of Biological Chemistry 288 (41), 29252-29259, 2013 | 216 | 2013 |
| Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping Z Liu, Y Zhang, S Graham, X Wang, D Cai, M Huang, R Pique-Regi, ... Journal of hepatology 73 (2), 263-276, 2020 | 214 | 2020 |
| Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6 [S] R Tao, X Xiong, RA DePinho, CX Deng, XC Dong Journal of lipid research 54 (10), 2745-2753, 2013 | 208 | 2013 |
| Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene R Tao, D Wei, H Gao, Y Liu, RA DePinho, XC Dong Journal of biological chemistry 286 (16), 14681-14690, 2011 | 156 | 2011 |
| The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice HG Kim, M Huang, Y Xin, Y Zhang, X Zhang, G Wang, S Liu, J Wan, ... Journal of hepatology 71 (5), 960-969, 2019 | 129 | 2019 |
| AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity G He, YW Zhang, JH Lee, SX Zeng, YV Wang, Z Luo, XC Dong, B Viollet, ... Molecular and cellular biology 34 (2), 148-157, 2014 | 128 | 2014 |
| Insulin receptor substrate signaling suppresses neonatal autophagy in the heart C Riehle, AR Wende, S Sena, KM Pires, RO Pereira, Y Zhu, H Bugger, ... The Journal of clinical investigation 123 (12), 5319-5333, 2013 | 128 | 2013 |
| Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis X Xiong, R Tao, RA DePinho, XC Dong PloS one 8 (8), e74340, 2013 | 118 | 2013 |
| Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling R Tao, X Xiong, S Liangpunsakul, XC Dong Diabetes 64 (4), 1211-1223, 2015 | 116 | 2015 |
| Inactivating hepatic follistatin alleviates hyperglycemia R Tao, C Wang, O Stöhr, W Qiu, Y Hu, J Miao, XC Dong, S Leng, ... Nature medicine 24 (7), 1058-1069, 2018 | 100 | 2018 |
| Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells X Xiong, G Wang, R Tao, P Wu, T Kono, K Li, WX Ding, X Tong, SA Tersey, ... Diabetologia 59, 151-160, 2016 | 80 | 2016 |
| PNPLA3—a potential therapeutic target for personalized treatment of chronic liver disease XC Dong Frontiers in medicine 6, 304, 2019 | 74 | 2019 |
| SIRT6 protects against liver fibrosis by deacetylation and suppression of SMAD3 in hepatic stellate cells X Zhong, M Huang, HG Kim, Y Zhang, K Chowdhury, W Cai, R Saxena, ... Cellular and molecular gastroenterology and hepatology 10 (2), 341-364, 2020 | 72 | 2020 |
| Genetic inactivation of pyruvate dehydrogenase kinases improves hepatic insulin resistance induced diabetes R Tao, X Xiong, RA Harris, MF White, XC Dong PloS one 8 (8), e71997, 2013 | 66 | 2013 |
| FOXO transcription factors protect against the diet-induced fatty liver disease X Pan, Y Zhang, HG Kim, S Liangpunsakul, XC Dong Scientific reports 7 (1), 44597, 2017 | 65 | 2017 |
| A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes S Zhang, S Liu, R Tao, D Wei, L Chen, W Shen, ZH Yu, L Wang, ... Journal of the American Chemical Society 134 (43), 18116-18124, 2012 | 63 | 2012 |
