CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations C Kuscu, M Parlak, T Tufan, J Yang, K Szlachta, X Wei, R Mammadov, ... Nature methods 14 (7), 710-712, 2017 | 406 | 2017 |
CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response K Szlachta, C Kuscu, T Tufan, SJ Adair, S Shang, AD Michaels, ... Nature communications 9 (1), 4275, 2018 | 84 | 2018 |
DNA damage in major psychiatric diseases MU Raza, T Tufan, Y Wang, C Hill, MY Zhu Neurotoxicity research 30, 251-267, 2016 | 77 | 2016 |
Super-enhancers maintain renin-expressing cell identity and memory to preserve multi-system homeostasis MF Martinez, S Medrano, RI Brown, T Tufan, S Shang, N Bertoncello, ... The Journal of clinical investigation 128 (11), 4787-4803, 2024 | 50 | 2024 |
Chemotherapy-induced distal enhancers drive transcriptional programs to maintain the chemoresistant state in ovarian cancer S Shang, J Yang, AA Jazaeri, AJ Duval, T Tufan, N Lopes Fischer, ... Cancer research 79 (18), 4599-4611, 2019 | 46 | 2019 |
Temporal and spatial epigenome editing allows precise gene regulation in mammalian cells C Kuscu, R Mammadov, A Czikora, H Unlu, T Tufan, NL Fischer, S Arslan, ... Journal of molecular biology 431 (1), 111-121, 2019 | 42 | 2019 |
Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation S Morioka, D Kajioka, Y Yamaoka, RM Ellison, T Tufan, IL Werkman, ... Cell 185 (26), 4887-4903. e17, 2022 | 28 | 2022 |
Recurrent mutations at estrogen receptor binding sites alter chromatin topology and distal gene expression in breast cancer J Yang, X Wei, T Tufan, C Kuscu, H Unlu, S Farooq, E Demirtas, ... Genome biology 19, 1-15, 2018 | 24 | 2018 |
Micro RNA s 29b and 181a down‐regulate the expression of the norepinephrine transporter and glucocorticoid receptors in PC 12 cells M Deng, T Tufan, MU Raza, TC Jones, MY Zhu Journal of Neurochemistry 139 (2), 197-207, 2016 | 23 | 2016 |
Pannexin 1 drives efficient epithelial repair after tissue injury CD Lucas, CB Medina, FA Bruton, DA Dorward, MH Raymond, T Tufan, ... Science immunology 7 (71), eabm4032, 2022 | 18 | 2022 |
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer H Ozturk, H Cingoz, T Tufan, J Yang, SJ Adair, KS Tummala, C Kuscu, ... Developmental Cell 57 (11), 1331-1346. e9, 2022 | 17 | 2022 |
DNA metilasyonu M İzmirli, T Tufan, D Alptekin Arşiv Kaynak Tarama Dergisi 21 (4), 274-282, 2012 | 17 | 2012 |
Report of a new case with pentasomy X and novel clinical findings O Demirhan, N Tanriverdi, MB Yilmaz, S Kocaturk-Sel, N Inandiklioglu, ... Balkan Journal of Medical Genetics 18 (1), 85-92, 2015 | 13 | 2015 |
Corticotropin releasing factor up‐regulates the expression and function of norepinephrine transporter in SK‐N‐BE (2) M17 cells J Huang, T Tufan, M Deng, G Wright, MY Zhu Journal of neurochemistry 135 (1), 38-49, 2015 | 13 | 2015 |
Restoration of noradrenergic function in Parkinson’s disease model mice K Cui, F Yang, T Tufan, MU Raza, Y Zhan, Y Fan, F Zeng, RW Brown, ... ASN neuro 13, 17590914211009730, 2021 | 12 | 2021 |
DNA methylation M İzmirli, T Tufan, D Alptekin Arşiv Kaynak Tarama Dergisi (Archives Medical Review Journal) 21 (4), 274-282, 2012 | 7 | 2012 |
Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release T Tufan, G Comertpay, A Villani, GM Nelson, M Terekhova, S Kelley, ... Nature 628 (8007), 408-415, 2024 | 6 | 2024 |
ATP sensitive K+ channel subunits (Kir6.1, Kir6.2) are the candidate mediators regulating ameliorating effects of pulsed magnetic field on aortic contractility in … I Ocal, MB Yilmaz, S Kocaturk‐Sel, T Tufan, MA Erkoc, G Comertpay, ... Bioelectromagnetics 39 (4), 299-311, 2018 | 4 | 2018 |
ISL2 is an epigenetically silenced tumor suppressor and regulator of metabolism in pancreatic cancer T Tufan, J Yang, KS Tummala, H Cingoz, C Kuscu, SJ Adair, G Comertpay, ... bioRxiv, 2020.05. 23.112839, 2020 | 1 | 2020 |
Investigation of the effects of nicotine and resveratrol on expression levels of Sox2 and Sox4 genes in human amniotic cell culture by real time PCR G Cömertpay, Ü Lüleyap, MB Yılmaz, T Tufan, P Pazarcı Cukurova Medical Journal 43 (1), 7-12, 2018 | 1 | 2018 |