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Simon Boulton
Simon Boulton
Principal Group Leader, The Francis Crick Institute
Dirección de correo verificada de crick.ac.uk
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Año
Playing the end game: DNA double-strand break repair pathway choice
JR Chapman, MRG Taylor, SJ Boulton
Molecular cell 47 (4), 497-510, 2012
20172012
Double-strand break repair: 53BP1 comes into focus
S Panier, SJ Boulton
Nature reviews Molecular cell biology 15 (1), 7-18, 2014
13242014
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
R Ceccaldi, JC Liu, R Amunugama, I Hajdu, B Primack, MIR Petalcorin, ...
Nature 518 (7538), 258-262, 2015
9212015
Components of the Ku‐dependent non‐homologous end‐joining pathway are involved in telomeric length maintenance and telomeric silencing
SJ Boulton, SP Jackson
The EMBO journal, 1998
8421998
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection
JR Chapman, P Barral, JB Vannier, V Borel, M Steger, A Tomas-Loba, ...
Molecular cell 49 (5), 858-871, 2013
7622013
Poly (ADP-ribose)–dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1
D Ahel, Z Hořejší, N Wiechens, SE Polo, E Garcia-Wilson, I Ahel, H Flynn, ...
science 325 (5945), 1240-1243, 2009
6762009
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double‐strand break repair and serves as a barrier to error‐prone DNA repair pathways.
SJ Boulton, SP Jackson
The EMBO journal 15 (18), 5093-5103, 1996
6491996
Identification of a Saccharomyces Cerevisiae Ku80 Homologue: Roles in DNA Double Strand Break Rejoining and in Telomeric Maintenance
SJ Boulton, SP Jackson
Nucleic acids research 24 (23), 4639-4648, 1996
6451996
REV7 counteracts DNA double-strand break resection and affects PARP inhibition
G Xu, JR Chapman, I Brandsma, J Yuan, M Mistrik, P Bouwman, ...
Nature 521 (7553), 541-544, 2015
6272015
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity
JB Vannier, V Pavicic-Kaltenbrunner, MIR Petalcorin, H Ding, SJ Boulton
Cell 149 (4), 795-806, 2012
5532012
Poly (ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
I Ahel, D Ahel, T Matsusaka, AJ Clark, J Pines, SJ Boulton, SC West
Nature 451 (7174), 81-85, 2008
5102008
RTEL1 maintains genomic stability by suppressing homologous recombination
LJ Barber, JL Youds, JD Ward, MJ McIlwraith, NJ O'Neil, MIR Petalcorin, ...
Cell 135 (2), 261-271, 2008
4702008
C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression
J Reboul, P Vaglio, JF Rual, P Lamesch, M Martinez, CM Armstrong, S Li, ...
Nature genetics 34 (1), 35-41, 2003
4492003
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis
B Schumacher, K Hofmann, S Boulton, A Gartner
Current biology 11 (21), 1722-1727, 2001
4472001
Cellular functions of the BRCA tumour-suppressor proteins
SJ Boulton
Biochemical Society Transactions 34 (5), 633-645, 2006
4052006
Mechanisms of oncogene-induced replication stress: jigsaw falling into place
P Kotsantis, E Petermann, SJ Boulton
Cancer discovery 8 (5), 537-555, 2018
4002018
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
JR Chapman, AJ Sossick, SJ Boulton, SP Jackson
Journal of cell science 125 (15), 3529-3534, 2012
3942012
Combined Functional Genomic Maps of the C. elegans DNA Damage Response
SJ Boulton, A Gartner, J Reboul, P Vaglio, N Dyson, DE Hill, M Vidal
Science 295 (5552), 127-131, 2002
3402002
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia
A Adamo, SJ Collis, CA Adelman, N Silva, Z Horejsi, JD Ward, ...
Molecular cell 39 (1), 25-35, 2010
3362010
Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis
ER Hofmann, S Milstein, SJ Boulton, M Ye, JJ Hofmann, L Stergiou, ...
Current biology 12 (22), 1908-1918, 2002
3132002
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Artículos 1–20