Luspatercept in patients with lower-risk myelodysplastic syndromes P Fenaux, U Platzbecker, GJ Mufti, G Garcia-Manero, R Buckstein, ... New England Journal of Medicine 382 (2), 140-151, 2020 | 557 | 2020 |
The generation of antibody diversity through somatic hypermutation and class switch recombination Z Li, CJ Woo, MD Iglesias-Ussel, D Ronai, MD Scharff Genes & development 18 (1), 1-11, 2004 | 486 | 2004 |
Fibroblast activation protein cleaves and inactivates fibroblast growth factor 21 DR Dunshee, TW Bainbridge, NM Kljavin, J Zavala-Solorio, ... Journal of Biological Chemistry 291 (11), 5986-5996, 2016 | 157 | 2016 |
Sustained brown fat stimulation and insulin sensitization by a humanized bispecific antibody agonist for fibroblast growth factor receptor 1/βKlotho complex G Kolumam, MZ Chen, R Tong, J Zavala-Solorio, L Kates, N van Bruggen, ... EBioMedicine 2 (7), 730-743, 2015 | 120 | 2015 |
Examination of Msh6-and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification Z Li, SJ Scherer, D Ronai, MD Iglesias-Ussel, JU Peled, PD Bardwell, ... Journal of Experimental Medicine 200 (1), 47-59, 2004 | 116 | 2004 |
Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation D Ronai, MD Iglesias-Ussel, M Fan, Z Li, A Martin, MD Scharff The Journal of experimental medicine 204 (1), 181-190, 2007 | 101 | 2007 |
Negative supercoiling creates single-stranded patches of DNA that are substrates for aid–mediated mutagenesis JY Parsa, S Ramachandran, A Zaheen, RM Nepal, A Kapelnikov, ... PLoS genetics 8 (2), e1002518, 2012 | 75 | 2012 |
Variegated expression of the endogenous immunoglobulin heavy-chain gene in the absence of the intronic locus control region D Ronai, M Berru, MJ Shulman Molecular and cellular biology 19 (10), 7031-7040, 1999 | 62 | 1999 |
Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans C Chi, D Ronai, MT Than, CJ Walker, AK Sewell, M Han Genes & development 30 (3), 307-320, 2016 | 49 | 2016 |
The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies Z Luo, D Ronai, MD Scharff Journal of allergy and clinical immunology 114 (4), 726-735, 2004 | 46 | 2004 |
Selective homogeneous assay for circulating endopeptidase fibroblast activation protein (FAP) TW Bainbridge, DR Dunshee, NM Kljavin, NJ Skelton, J Sonoda, JA Ernst Scientific Reports 7 (1), 12524, 2017 | 35 | 2017 |
Unliganded fibroblast growth factor receptor 1 forms density-independent dimers L Comps-Agrar, DR Dunshee, DL Eaton, J Sonoda Journal of Biological Chemistry 290 (40), 24166-24177, 2015 | 35 | 2015 |
Mosunetuzumab monotherapy continues to demonstrate promising efficacy and durable complete responses in elderly/unfit patients with previously untreated diffuse large B-cell … AJ Olszewski, A Avigdor, S Babu, I Levi, H Eradat, U Abadi, H Holmes, ... Blood 140 (Supplement 1), 1778-1780, 2022 | 33 | 2022 |
Complex regulation of somatic hypermutation by cis-acting sequences in the endogenous IgH gene in hybridoma cells D Ronai, MD Iglesias-Ussel, M Fan, MJ Shulman, MD Scharff Proceedings of the National Academy of Sciences 102 (33), 11829-11834, 2005 | 33 | 2005 |
Role of the intronic elements in the endogenous immunoglobulin heavy chain locus: either the matrix attachment regions or the core enhancer is sufficient to maintain expression EJ Wiersma, D Ronai, M Berru, FWL Tsui, MJ Shulman Journal of Biological Chemistry 274 (8), 4858-4862, 1999 | 30 | 1999 |
A role for Mlh3 in somatic hypermutation Z Li, JU Peled, C Zhao, A Svetlanov, D Ronai, PE Cohen, MD Scharff dna repair 5 (6), 675-682, 2006 | 29 | 2006 |
Molecular responses are observed across mutational spectrum in treatment-naïve higher-risk myelodysplastic syndrome patients treated with venetoclax plus azacitidine JS Garcia, AH Wei, MA Jacoby, CY Fong, U Borate, MR Baer, ... Blood 138, 241, 2021 | 27 | 2021 |
An efficient route to bispecific antibody production using single-reactor mammalian co-culture W Shatz, D Ng, G Dutina, AW Wong, DR Dunshee, J Sonoda, A Shen, ... MAbs 8 (8), 1487-1497, 2016 | 26 | 2016 |
Mosunetuzumab and polatuzumab vedotin demonstrates preliminary efficacy in elderly unfit/frail patients with previously untreated diffuse large B-cell lymphoma AJ Olszewski, H Eradat, A Avigdor, NA Horowitz, S Babu, I Levi, ... Blood 142, 855, 2023 | 16 | 2023 |
Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening HS Kim, DR Dunshee, A Yee, RK Tong, I Kim, F Farahi, JA Hongo, ... Protein Engineering, Design and Selection 30 (9), 627-637, 2017 | 10 | 2017 |