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Keir Menzies
Keir Menzies
Associate Professor, University of Ottawa
Dirección de correo verificada de uottawa.ca - Página principal
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NAD+ metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus
C Cantó, KJ Menzies, J Auwerx
Cell metabolism 22 (1), 31-53, 2015
16392015
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
H Zhang, D Ryu, Y Wu, K Gariani, X Wang, P Luan, D D’Amico, ...
Science 352 (6292), 1436-1443, 2016
12342016
Mitochondrial function and apoptotic susceptibility in aging skeletal muscle
B Chabi, V Ljubicic, KJ Menzies, JH Huang, A Saleem, DA Hood
Aging cell 7 (1), 2-12, 2008
5082008
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice
K Gariani, KJ Menzies, D Ryu, CJ Wegner, X Wang, ER Ropelle, ...
Hepatology 63 (4), 1190-1204, 2016
3992016
Protein acetylation in metabolism—metabolites and cofactors
KJ Menzies, H Zhang, E Katsyuba, J Auwerx
Nature Reviews Endocrinology 12 (1), 43-60, 2016
3482016
Repairing mitochondrial dysfunction in disease
V Sorrentino, KJ Menzies, J Auwerx
Annual review of pharmacology and toxicology 58 (1), 353-389, 2018
3002018
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation
D Ryu, H Zhang, ER Ropelle, V Sorrentino, DAG Mázala, L Mouchiroud, ...
Science translational medicine 8 (361), 361ra139-361ra139, 2016
2922016
Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle
E Pirinen, C Canto, YS Jo, L Morato, H Zhang, KJ Menzies, EG Williams, ...
Cell metabolism 19 (6), 1034-1041, 2014
2892014
The role of mitochondria in stem cell fate and aging
H Zhang, KJ Menzies, J Auwerx
Development 145 (8), dev143420, 2018
2782018
Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis
KJ Menzies, K Singh, A Saleem, DA Hood
Journal of Biological Chemistry 288 (10), 6968-6979, 2013
2122013
Differential susceptibility of subsarcolemmal and intermyofibrillar mitochondria to apoptotic stimuli
PJ Adhihetty, V Ljubicic, KJ Menzies, DA Hood
American journal of physiology-cell physiology 289 (4), C994-C1001, 2005
2042005
Sarcopenia and muscle aging: a brief overview
T Dao, AE Green, YA Kim, SJ Bae, KT Ha, K Gariani, M Lee, KJ Menzies, ...
Endocrinology and metabolism 35 (4), 716-732, 2020
1732020
Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease
K Gariani, D Ryu, KJ Menzies, HS Yi, S Stein, H Zhang, A Perino, ...
Journal of hepatology 66 (1), 132-141, 2017
1722017
SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis
G Lo Sasso, KJ Menzies, A Mottis, A Piersigilli, A Perino, H Yamamoto, ...
PloS one 9 (7), e103573, 2014
1402014
SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport
S Stein, MH Oosterveer, C Mataki, P Xu, V Lemos, R Havinga, C Dittner, ...
Cell metabolism 20 (4), 603-613, 2014
882014
Relationship between Sirt1 expression and mitochondrial proteins during conditions of chronic muscle use and disuse
B Chabi, PJ Adhihetty, MFN O'Leary, KJ Menzies, DA Hood
Journal of applied physiology 107 (6), 1730-1735, 2009
852009
Exercise-induced mitochondrial biogenesis in skeletal muscle
DA Hood, A Saleem
Nutrition, Metabolism and Cardiovascular Diseases 17 (5), 332-337, 2007
712007
The role of SirT1 in muscle mitochondrial turnover
KJ Menzies, DA Hood
Mitochondrion 12 (1), 5-13, 2012
662012
Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress
G Vasam, R Nadeau, VJJ Cadete, M Lavallée‐Adam, KJ Menzies, ...
The FASEB Journal 35 (4), e21278, 2021
612021
Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle
V Ljubicic, KJ Menzies, DA Hood
Mechanisms of ageing and development 131 (2), 79-88, 2010
542010
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Artículos 1–20