IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models H Ågerstam, N Hansen, S von Palffy, C Sandén, K Reckzeh, C Karlsson, ... Blood, The Journal of the American Society of Hematology 128 (23), 2683-2693, 2016 | 107 | 2016 |
Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche M Rehn, A Olsson, K Reckzeh, E Diffner, P Carmeliet, G Landberg, ... Blood, The Journal of the American Society of Hematology 118 (6), 1534-1543, 2011 | 97 | 2011 |
The tetraspanin CD9 affords high-purity capture of all murine hematopoietic stem cells G Karlsson, E Rörby, C Pina, S Soneji, K Reckzeh, K Miharada, ... Cell reports 4 (4), 642-648, 2013 | 60 | 2013 |
Molecular mechanisms underlying deregulation of C/EBPα in acute myeloid leukemia K Reckzeh, J Cammenga International journal of hematology 91, 557-568, 2010 | 56 | 2010 |
Copper related toxic effects on cellular protein metabolism in human astrocytes K Merker, D Hapke, K Reckzeh, H Schmidt, H Lochs, T Grune Biofactors 24 (1-4), 255-261, 2005 | 46 | 2005 |
Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model K Reckzeh, O Bereshchenko, A Mead, M Rehn, S Kharazi, SE Jacobsen, ... Leukemia 26 (7), 1527-1536, 2012 | 42 | 2012 |
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML JS Jakobsen, LG Laursen, MB Schuster, S Pundhir, E Schoof, Y Ge, ... Science advances 5 (7), eaaw4304, 2019 | 41 | 2019 |
Low‐molecular‐weight carbohydrate Pentaisomaltose may replace dimethyl sulfoxide as a safer cryoprotectant for cryopreservation of peripheral blood stem cells JD Svalgaard, EK Haastrup, K Reckzeh, B Holst, PV Glovinski, JS Gørløv, ... Transfusion 56 (5), 1088-1095, 2016 | 36 | 2016 |
Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD–induced myeloproliferation S Kharazi, AJ Mead, A Mansour, A Hultquist, C Böiers, S Luc, ... Blood, The Journal of the American Society of Hematology 118 (13), 3613-3621, 2011 | 34 | 2011 |
The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers CF Nielsen, SM van Putten, IK Lund, MC Melander, KS Nørregaard, ... Oncotarget 8 (27), 44605, 2017 | 32 | 2017 |
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard K Theilgaard-Mönch, S Pundhir, K Reckzeh, J Su, M Tapia, B Furtwängler, ... Nature Communications 13 (1), 3595, 2022 | 22 | 2022 |
Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin K Reckzeh, H Kizilkaya, AS Helbo, ME Alrich, AG Deslauriers, A Grover, ... Blood advances 2 (13), 1628-1632, 2018 | 18 | 2018 |
Targeted inhibition of cooperative mutation-and therapy-induced AKT activation in AML effectively enhances response to chemotherapy M Estruch, K Reckzeh, C Vittori, A Centio, M Ali, S Engelhard, L Zhao, ... Leukemia 35 (7), 2030-2042, 2021 | 15 | 2021 |
Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML A Pfeiffer, G Franciosa, M Locard-Paulet, I Piga, K Reckzeh, ... Cancer research 82 (11), 2141-2155, 2022 | 13 | 2022 |
Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia: a novel therapeutic strategy to boost chemotherapy response and overcome resistance M Estruch, C Vittori, TM Montesinos, K Reckzeh, K Theilgaard-Mönch Cancer Drug Resistance 4 (4), 984, 2021 | 8 | 2021 |
Inhibition of oxidized nucleotide sanitation by TH1579 and conventional chemotherapy cooperatively enhance oxidative DNA damage and survival in AML A Centio, M Estruch, K Reckzeh, K Sanjiv, C Vittori, S Engelhard, ... Molecular Cancer Therapeutics 21 (5), 703-714, 2022 | 5 | 2022 |
TET2 deficiency cooperates with CBFB‐MYH11 to induce acute myeloid leukaemia and represents an early leukaemogenic event. K Reckzeh, M Estruch, M Ali, A Søgaard Helbo, A Mosbech, K Jae Won, ... British Journal of Haematology 197 (2), 2022 | 5 | 2022 |
SMAD4 sequestrates HOXA9 to protect hematopoietic stem cells against leukemia transformation R Quere, G Karlsson, F Hertwig, M Rissler, B Lindqvist, T Fioretos, ... Blood, The Journal of the American Society of Hematology 116 (21), 3153-3153, 2010 | 2 | 2010 |
Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration S Engelhard, M Estruch, S Qin, CA Engelhard, FG Rodriguez-Gonzalez, ... Cell reports 43 (7), 2024 | 1 | 2024 |
Novel Combination Treatments for AML M Estruch, C Vittori, T Muñoz-Montesinos, K Reckzeh, ... Journal of Cellular Immunology 3 (4), 240-245, 2021 | 1 | 2021 |