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Claire Nicole Bedbrook
Claire Nicole Bedbrook
Dirección de correo verificada de stanford.edu
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Learned protein embeddings for machine learning
KK Yang, Z Wu, CN Bedbrook, FH Arnold
Bioinformatics 34 (15), 2642-2648, 2018
3652018
The jellyfish Cassiopea exhibits a sleep-like state
RD Nath, CN Bedbrook, MJ Abrams, T Basinger, JS Bois, DA Prober, ...
Current Biology 27 (19), 2984-2990. e3, 2017
2832017
Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics
CN Bedbrook, KK Yang, JE Robinson, ED Mackey, V Gradinaru, ...
Nature methods 16 (11), 1176-1184, 2019
2232019
Viral strategies for targeting the central and peripheral nervous systems
CN Bedbrook, BE Deverman, V Gradinaru
Annual review of neuroscience 41 (1), 323-348, 2018
1802018
Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons
NC Flytzanis, CN Bedbrook, H Chiu, MKM Engqvist, C Xiao, KY Chan, ...
Nature communications 5 (1), 4894, 2014
1682014
Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization
CN Bedbrook, KK Yang, AJ Rice, V Gradinaru, FH Arnold
PLoS computational biology 13 (10), e1005786, 2017
1342017
Directed evolution of a bright near-infrared fluorescent rhodopsin using a synthetic chromophore
L Herwig, AJ Rice, CN Bedbrook, RK Zhang, A Lignell, JKB Cahn, ...
Cell chemical biology 24 (3), 415-425, 2017
702017
Genetically encoded spy peptide fusion system to detect plasma membrane-localized proteins in vivo
CN Bedbrook, M Kato, SR Kumar, A Lakshmanan, RD Nath, F Sun, ...
Chemistry & biology 22 (8), 1108-1121, 2015
692015
Recent advances in engineering microbial rhodopsins for optogenetics
RS McIsaac, CN Bedbrook, FH Arnold
Current opinion in structural biology 33, 8-15, 2015
622015
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
CN Bedbrook, AJ Rice, KK Yang, X Ding, S Chen, EM LeProust, ...
Proceedings of the National Academy of Sciences 114 (13), E2624-E2633, 2017
602017
An automated feeding system for the African killifish reveals the impact of diet on lifespan and allows scalable assessment of associative learning
A McKay, EK Costa, J Chen, CK Hu, X Chen, CN Bedbrook, RC Khondker, ...
Elife 11, e69008, 2022
242022
Hypocrea jecorina Cellobiohydrolase I Stabilizing Mutations Identified Using Noncontiguous Recombination
MA Smith, CN Bedbrook, T Wu, FH Arnold
ACS synthetic biology 2 (12), 690-696, 2013
242013
Rapid and precise genome engineering in a naturally short-lived vertebrate
CN Bedbrook, RD Nath, R Nagvekar, K Deisseroth, A Brunet
Elife 12, e80639, 2023
112023
Husbandry of the African turquoise killifish Nothobranchius furzeri
RD Nath, CN Bedbrook, R Nagvekar, A Brunet
Cold Spring Harbor Protocols 2023 (6), pdb. prot107738, 2023
62023
Rapid and precise genome engineering in a naturally short-lived vertebrate
RD Nath, CN Bedbrook, R Nagvekar, K Deisseroth, A Brunet
bioRxiv, 2022.05. 25.493454, 2022
52022
Engineered light-sensitive proteins
V Gradinaru, CN Bedbrook, FH Arnold, KK Yang
US Patent 11,858,969, 2024
22024
Life span assessment in the African turquoise killifish Nothobranchius furzeri
CN Bedbrook, RD Nath, R Barajas, A Brunet
Cold Spring Harbor Protocols 2023 (6), pdb. prot107917, 2023
12023
Neuronal activity sensing and modulation with Archers
N Flytzanis, C Bedbrook, V Gradinaru
SPIE Newsroom, 2014
12014
Engineered light-sensitive proteins
V Gradinaru, CN Bedbrook, FH Arnold, KK Yang
US Patent App. 18/517,703, 2024
2024
Engineering Novel Rhodopsins for Neuroscience
CN Bedbrook
California Institute of Technology, 2018
2018
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Artículos 1–20