| Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR AH Tolson, H Wang Advanced drug delivery reviews 62 (13), 1238-1249, 2010 | 452 | 2010 |
| Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes H Wang, EL LeCluyse Clinical pharmacokinetics 42, 1331-1357, 2003 | 386 | 2003 |
| CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme H Wang, LM Tompkins Current drug metabolism 9 (7), 598-610, 2008 | 355 | 2008 |
| Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers SR Faucette, TC Zhang, R Moore, T Sueyoshi, CJ Omiecinski, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 72-80, 2007 | 345 | 2007 |
| Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers SR Faucette, H Wang, GA Hamilton, SL Jolley, D Gilbert, C Lindley, B Yan, ... Drug Metabolism and Disposition 32 (3), 348-358, 2004 | 269 | 2004 |
| A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression H Wang, S Faucette, T Sueyoshi, R Moore, S Ferguson, M Negishi, ... Journal of Biological Chemistry 278 (16), 14146-14152, 2003 | 258 | 2003 |
| Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor SR Faucette, T Sueyoshi, CM Smith, M Negishi, EL LeCluyse, H Wang Journal of Pharmacology and Experimental Therapeutics 317 (3), 1200-1209, 2006 | 225 | 2006 |
| Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane … L Li, JD Stanton, AH Tolson, Y Luo, H Wang Pharmaceutical research 26, 872-882, 2009 | 189 | 2009 |
| Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin H Wang, S Faucette, R Moore, T Sueyoshi, M Negishi, E LeCluyse Journal of Biological Chemistry 279 (28), 29295-29301, 2004 | 187 | 2004 |
| Mechanisms of xenobiotic receptor activation: Direct vs. indirect B Mackowiak, H Wang Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (9 …, 2016 | 155 | 2016 |
| Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors H Wang, M Negishi Current drug metabolism 4 (6), 515-525, 2003 | 154 | 2003 |
| 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration H Wang, PC Brown, ECY Chow, L Ewart, SS Ferguson, S Fitzpatrick, ... Clinical and translational science 14 (5), 1659-1680, 2021 | 151 | 2021 |
| Insights into CYP2B6-mediated drug–drug interactions WD Hedrich, HE Hassan, H Wang Acta Pharmaceutica Sinica B 6 (5), 413-425, 2016 | 149 | 2016 |
| Signaling control of the constitutive androstane receptor (CAR) H Yang, H Wang Protein & cell 5 (2), 113-123, 2014 | 134 | 2014 |
| Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice A Xu, H Wang, RLC Hoo, G Sweeney, PM Vanhoutte, Y Wang, D Wu, ... Endocrinology 150 (2), 625-633, 2009 | 131 | 2009 |
| Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes H Wang, SR Faucette, D Gilbert, SL Jolley, T Sueyoshi, M Negishi, ... Drug Metabolism and Disposition 31 (5), 620-630, 2003 | 127 | 2003 |
| The roles of xenobiotic receptors: beyond chemical disposition B Mackowiak, J Hodge, S Stern, H Wang Drug Metabolism and Disposition 46 (9), 1361-1371, 2018 | 126 | 2018 |
| The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor L Li, T Chen, JD Stanton, T Sueyoshi, M Negishi, H Wang Molecular pharmacology 74 (2), 443-453, 2008 | 124 | 2008 |
| The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes C Lindley, G Hamilton, JS McCune, S Faucette, SS Shord, RL Hawke, ... Drug metabolism and disposition 30 (7), 814-822, 2002 | 119 | 2002 |
| 17-hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer … Y Wang, X Ma, S Yan, S Shen, H Zhu, Y Gu, H Wang, G Qin, Q Yu Cancer research 69 (18), 7302-7310, 2009 | 111 | 2009 |
Peter SwaanProfessor and Dean, College of Pharmacy, University of FloridaDirección de correo verificada de rx.umaryland.edu