| Process analytical technique (PAT) miniaturization for monoclonal antibody aggregate detection in continuous downstream processing MN São Pedro, ME Klijn, MHM Eppink, M Ottens Journal of Chemical Technology & Biotechnology 97 (9), 2347-2364, 2022 | 31 | 2022 |
| Prediction of protein retention times in hydrophobic interaction chromatography by robust statistical characterization of their atomic‐level surface properties AT Hanke, ME Klijn, PDEM Verhaert, LAM van der Wielen, M Ottens, ... Biotechnology progress 32 (2), 372-381, 2016 | 21 | 2016 |
| Application of ultraviolet, visible, and infrared light imaging in protein-based biopharmaceutical formulation characterization and development studies ME Klijn, J Hubbuch European Journal of Pharmaceutics and Biopharmaceutics 165, 319-336, 2021 | 20 | 2021 |
| Application of empirical phase diagrams for multidimensional data visualization of high-throughput microbatch crystallization experiments ME Klijn, J Hubbuch Journal of Pharmaceutical Sciences 107 (8), 2063-2069, 2018 | 13 | 2018 |
| Correlating multidimensional short-term empirical protein properties to long-term protein physical stability data via empirical phase diagrams ME Klijn, J Hubbuch International Journal of Pharmaceutics 560, 166-174, 2019 | 8 | 2019 |
| Time-dependent multi-light-source image classification combined with automated multidimensional protein phase diagram construction for protein phase behavior analysis ME Klijn, J Hubbuch Journal of pharmaceutical sciences 109 (1), 331-339, 2020 | 6 | 2020 |
| Apparent protein cloud point temperature determination using a low volume high-throughput cryogenic device in combination with automated imaging ME Klijn, AK Wöll, J Hubbuch Bioprocess and biosystems engineering 43, 439-456, 2020 | 4 | 2020 |
| High-throughput computational pipeline for 3-D structure preparation and in silico protein surface property screening: a case study on HBcAg dimer structures ME Klijn, P Vormittag, N Bluthardt, J Hubbuch International Journal of Pharmaceutics 563, 337-346, 2019 | 4 | 2019 |
| Experimental characterization and prediction of Escherichia coli host cell proteome retention during preparative chromatography R Disela, T Neijenhuis, O Le Bussy, G Geldhof, M Klijn, M Pabst, M Ottens Biotechnology and Bioengineering 121 (12), 3848-3859, 2024 | 2 | 2024 |
| Predicting protein retention in ion‐exchange chromatography using an open source QSPR workflow T Neijenhuis, O Le Bussy, G Geldhof, ME Klijn, M Ottens Biotechnology Journal 19 (3), 2300708, 2024 | 2 | 2024 |
| Redesigning food protein formulations with empirical phase diagrams: A case study on glycerol-poor and glycerol-free formulations ME Klijn, J Hubbuch Food Research International 125, 108609, 2019 | 2 | 2019 |
| Influence of image analysis strategy, cooling rate, and sample volume on apparent protein cloud-point temperature determination ME Klijn, J Hubbuch Bioprocess and biosystems engineering 44, 525-536, 2021 | 1 | 2021 |
| Single compound data supplementation to enhance transferability of fermentation specific Raman spectroscopy models M Klaverdijk, M Ottens, ME Klijn Analytical and Bioanalytical Chemistry, 1-12, 2025 | | 2025 |
| From protein structure to an optimized chromatographic capture step using multiscale modeling D Keulen, T Neijenhuis, A Lazopoulou, R Disela, G Geldhof, O Le Bussy, ... Biotechnology Progress, e3505, 2024 | | 2024 |
| Combination of Raman spectroscopy and in‐line microscopy monitoring for yeast fermentation M Klaverdijk, M Klijn, M Ottens Chemie Ingenieur Technik 94 (9), 1286-1286, 2022 | | 2022 |
| Automated, high-throughput, and computational methods for construction and analysis of protein phase diagrams M Klijn, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| High-throughput computational pipeline for 3-D structure preparation and in silico protein surface property screening: A case study on HBcAg VLP surface charge P Vormittag, M Klijn, N Bluthardt, T Klamp, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Computational methods for long-term protein phase behavior analysis M Klijn Dissertation, Karlsruhe, Karlsruher Institut für Technologie (KIT), 2019, 2019 | | 2019 |
| Characterizing long-term protein phase behavior via multidimensional empirical protein phase diagrams containing image-based features M Klijn, J Hubbuch ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Multidimensional data visualization and data mining for characterization of long term protein phase behavior M Klijn ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
