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Eric Jay Earley
Eric Jay Earley
Genomics PLC
Dirección de correo verificada de genomicsinc.com - Página principal
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A menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia
AV Krivtsov, K Evans, JY Gadrey, BK Eschle, C Hatton, HJ Uckelmann, ...
Cancer cell 36 (6), 660-673. e11, 2019
3462019
The B7-H3–targeting antibody–drug conjugate m276-SL-PBD is potently effective against pediatric cancer preclinical solid tumor models
NM Kendsersky, J Lindsay, EA Kolb, MA Smith, BA Teicher, SW Erickson, ...
Clinical Cancer Research 27 (10), 2938-2946, 2021
862021
Inflorescences contribute more than rosettes to lifetime carbon gain in Arabidopsis thaliana (Brassicaceae)
EJ Earley, B Ingland, J Winkler, SJ Tonsor
American Journal of Botany 96 (4), 786-792, 2009
782009
Large genome-wide association study identifies three novel risk variants for restless legs syndrome
M Didriksen, MS Nawaz, J Dowsett, S Bell, C Erikstrup, OB Pedersen, ...
Communications biology 3 (1), 703, 2020
612020
Rapid and Predictable Evolution of Admixed Populations Between Two Drosophila Species Pairs
DR Matute, AA Comeault, E Earley, A Serrato-Capuchina, D Peede, ...
Genetics 214 (1), 211-230, 2020
462020
A Locus in Drosophila sechellia Affecting Tolerance of a Host Plant Toxin
EA Hungate, EJ Earley, IA Boussy, DA Turissini, CT Ting, JR Moran, ...
Genetics 195 (3), 1063-1075, 2013
422013
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 41 (21), e110393, 2022
382022
Next-generation mapping of complex traits with phenotype-based selection and introgression
EJ Earley, CD Jones
Genetics 189 (4), 1203-1209, 2011
362011
Comprehensive surfaceome profiling to identify and validate novel cell-surface targets in osteosarcoma
Y Wang, X Tian, W Zhang, Z Zhang, R Lazcano, P Hingorani, ME Roth, ...
Molecular cancer therapeutics 21 (6), 903-913, 2022
222022
Evaluation of an EZH2 inhibitor in patient-derived orthotopic xenograft models of pediatric brain tumors alone and in combination with chemo-and radiation therapies
L Qi, H Lindsay, M Kogiso, Y Du, FK Braun, H Zhang, L Guo, S Zhao, ...
Laboratory Investigation 102 (2), 185-193, 2022
202022
Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes
T Nemkov, D Stephenson, EJ Earley, GR Keele, A Hay, A Key, ZB Haiman, ...
Cell Metabolism 36 (9), 1979-1997. e13, 2024
172024
In vivo evaluation of the EZH2 inhibitor (EPZ011989) alone or in combination with standard of care cytotoxic agents against pediatric malignant rhabdoid tumor preclinical …
RT Kurmasheva, SW Erickson, E Earley, MA Smith, PJ Houghton
Pediatric blood & cancer 68 (2), e28772, 2021
172021
Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo
T Nemkov, D Stephenson, C Erickson, M Dzieciatkowska, A Key, A Moore, ...
Blood 143 (5), 456-472, 2024
162024
Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2, 3-bisphosphoglycerate in humans at high altitude
A D’alessandro, EJ Earley, T Nemkov, D Stephenson, M Dzieciatkowska, ...
Proceedings of the National Academy of Sciences 121 (1), e2315930120, 2024
162024
Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro
T Nemkov, A Key, D Stephenson, EJ Earley, GR Keele, A Hay, ...
Blood 143 (24), 2517-2533, 2024
132024
Paternally Inherited P-Element Copy Number Affects the Magnitude of Hybrid Dysgenesis in Drosophila simulans and D. melanogaster
A Serrato-Capuchina, J Wang, E Earley, D Peede, K Isbell, DR Matute
Genome Biology and Evolution 12 (6), 808-826, 2020
132020
Association of proton pump inhibitor and histamine H2-receptor antagonists with restless legs syndrome
EJ Earley, M Didriksen, BR Spencer, JE Kiss, C Erikstrup, OB Pedersen, ...
Sleep 44 (4), zsaa220, 2021
122021
Genome‐wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers …
EJ Earley, S Kelly, F Fang, CS Alencar, DOW Rodrigues, DT Soares Cruz, ...
British journal of haematology 201 (2), 343-352, 2023
62023
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 42 (3), e113326, 2023
62023
Recent invasion of P transposable element into Drosophila yakuba
A Serrato-Capuchina, S Zhang, W Martin, D Peede, E Earley, DR Matute
bioRxiv, 453829, 2018
62018
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Artículos 1–20