Intrinsically disordered regions direct transcription factor in vivo binding specificity S Brodsky*, T Jana*, K Mittelman, M Chapal, DK Kumar, M Carmi, ... Molecular cell 79 (3), 459-471. e4, 2020 | 287 | 2020 |
Order through disorder: The role of intrinsically disordered regions in transcription factor binding specificity S Brodsky*, T Jana*, N Barkai Current opinion in structural biology 71, 110-115, 2021 | 64 | 2021 |
Speed–specificity trade-offs in the transcription factors search for their genomic binding sites T Jana*, S Brodsky*, N Barkai Trends in Genetics, 2021 | 56 | 2021 |
Resolving noise–control conflict by gene duplication M Chapal, S Mintzer, S Brodsky, M Carmi, N Barkai PLoS biology 17 (11), e3000289, 2019 | 53 | 2019 |
Ubiquitin-independent proteasomal degradation driven by C-degron pathways Y Makaros, A Raiff, RT Timms, AR Wagh, MI Gueta, A Bekturova, ... Molecular Cell 83 (11), 1921-1935. e7, 2023 | 40 | 2023 |
Complementary strategies for directing in vivo transcription factor binding through DNA binding domains and intrinsically disordered regions DK Kumar, F Jonas, T Jana, S Brodsky, M Carmi, N Barkai Molecular cell 83 (9), 1462-1473. e5, 2023 | 37 | 2023 |
Transcription factor binding to replicated DNA R Bar-Ziv*, S Brodsky*, M Chapal, N Barkai Cell reports 30 (12), 3989-3995. e4, 2020 | 24 | 2020 |
The molecular grammar of protein disorder guiding genome-binding locations F Jonas, M Carmi, B Krupkin, J Steinberger, S Brodsky, T Jana, N Barkai Nucleic acids research 51 (10), 4831-4844, 2023 | 21 | 2023 |
Intrinsically disordered regions of the Msn2 transcription factor encode multiple functions using interwoven sequence grammars V Mindel*, S Brodsky*, A Cohen, W Manadre, F Jonas, M Carmi, N Barkai Nucleic Acids Research, gkad1191, 2023 | 12 | 2023 |
Phosphorylation of Serine 114 of the transcription factor ABSCISIC ACID INSENSITIVE 4 is essential for activity N Eisner, T Maymon, EC Sanchez, D Bar-Zvi, S Brodsky, R Finkelstein, ... Plant Science 305, 110847, 2021 | 10 | 2021 |
Pls1 is a peroxisomal matrix protein with a role in regulating lysine biosynthesis Y David, IG Castro, E Yifrach, C Bibi, E Katawi, D Yahav Har-Shai, ... Cells 11 (9), 1426, 2022 | 9 | 2022 |
Revisiting the model for coactivator recruitment: Med15 can select its target sites independent of promoter-bound transcription factors V Mindel*, S Brodsky*, H Yung, W Manadre, N Barkai Nucleic Acids Research, gkae718, 2024 | 5 | 2024 |
Massively Parallel Binding Assay (MPBA) reveals limited transcription factor binding cooperativity, challenging models of specificity T Jana Lang*, S Brodsky*, W Manadre, M Vidavski, G Valinsky, V Mindel, ... Nucleic Acids Research, gkae846, 2024 | 2 | 2024 |
Beyond RNA-binding domains: determinants of protein–RNA binding I Zigdon, M Carmi, S Brodsky, Z Rosenwaser, N Barkai, F Jonas RNA 30 (12), 1620-1633, 2024 | | 2024 |