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Gaurav Varshney, PhD
Gaurav Varshney, PhD
Genes & Human Disease Research Program
Dirección de correo verificada de omrf.org - Página principal
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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9
GK Varshney, W Pei, MC LaFave, J Idol, L Xu, V Gallardo, B Carrington, ...
Genome research 25 (7), 1030-1042, 2015
5842015
Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy
RJ Chandler, MC LaFave, GK Varshney, NS Trivedi, N Carrillo-Carrasco, ...
The Journal of clinical investigation 125 (2), 870-880, 2015
4022015
A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish
GK Varshney, B Carrington, W Pei, K Bishop, Z Chen, C Fan, L Xu, ...
Nature protocols 11 (12), 2357-2375, 2016
2212016
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion
C Englund, CE Lorén, C Grabbe, GK Varshney, F Deleuil, B Hallberg, ...
Nature 425 (6957), 512-516, 2003
1982003
Multiplex conditional mutagenesis using transgenic expression of Cas9 and sgRNAs
L Yin, LA Maddison, M Li, N Kara, MC LaFave, GK Varshney, SM Burgess, ...
Genetics 200 (2), 431-441, 2015
1842015
Expanding the CRISPR toolbox in zebrafish for studying development and disease
K Liu, C Petree, T Requena, P Varshney, GK Varshney
Frontiers in cell and developmental biology 7, 13, 2019
1542019
CRISPR-STAT: an easy and reliable PCR-based method to evaluate target-specific sgRNA activity
B Carrington, GK Varshney, SM Burgess, R Sood
Nucleic acids research 43 (22), e157-e157, 2015
1372015
A 3D searchable database of transgenic zebrafish Gal4 and Cre lines for functional neuroanatomy studies
GD Marquart, KM Tabor, M Brown, JL Strykowski, GK Varshney, ...
Frontiers in neural circuits 9, 78, 2015
1372015
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function
GK Varshney, J Lu, DE Gildea, H Huang, W Pei, Z Yang, SC Huang, ...
Genome research 23 (4), 727-735, 2013
1252013
MLV integration site selection is driven by strong enhancers and active promoters
MC LaFave, GK Varshney, DE Gildea, TG Wolfsberg, AD Baxevanis, ...
Nucleic acids research 42 (7), 4257-4269, 2014
1172014
Understanding and editing the zebrafish genome
GK Varshney, R Sood, SM Burgess
Advances in genetics 92, 1-52, 2015
1082015
A defined zebrafish line for high-throughput genetics and genomics: NHGRI-1
MC LaFave, GK Varshney, M Vemulapalli, JC Mullikin, SM Burgess
Genetics 198 (1), 167-170, 2014
1062014
Long-term correction of Sandhoff disease following intravenous delivery of rAAV9 to mouse neonates
JS Walia, N Altaleb, A Bello, C Kruck, MC LaFave, GK Varshney, ...
Molecular Therapy 23 (3), 414-422, 2015
972015
Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation
W Pei, K Tanaka, SC Huang, L Xu, B Liu, J Sinclair, J Idol, GK Varshney, ...
NPJ Regenerative medicine 1 (1), 1-11, 2016
722016
Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation
Y Yamazaki, C Schönherr, GK Varshney, M Dogru, B Hallberg, ...
The EMBO journal 32 (4), 524-537, 2013
662013
Genotoxicity in mice following AAV gene delivery: a safety concern for human gene therapy?
RJ Chandler, MC LaFave, GK Varshney, SM Burgess, CP Venditti
Molecular Therapy 24 (2), 198-201, 2016
652016
Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion
VE Gallardo, GK Varshney, M Lee, S Bupp, L Xu, P Shinn, NP Crawford, ...
Disease models & mechanisms 8 (6), 565-576, 2015
632015
Mutagenesis and phenotyping resources in zebrafish for studying development and human disease
GK Varshney, SM Burgess
Briefings in functional genomics 13 (2), 82-94, 2014
552014
CRISPRz: a database of zebrafish validated sgRNAs
GK Varshney, S Zhang, W Pei, A Adomako-Ankomah, J Fohtung, ...
Nucleic acids research 44 (D1), D822-D826, 2016
472016
GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126
MR Mahamud, X Geng, YC Ho, B Cha, Y Kim, J Ma, L Chen, G Myers, ...
Development 146 (21), dev184218, 2019
462019
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Artículos 1–20