| Direct conversion of fibroblasts into functional astrocytes by defined transcription factors M Caiazzo, S Giannelli, P Valente, G Lignani, A Carissimo, A Sessa, ... Stem cell reports 4 (1), 25-36, 2015 | 258 | 2015 |
| AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders V Salpietro, CL Dixon, H Guo, OD Bello, J Vandrovcova, S Efthymiou, ... Nature communications 10 (1), 3094, 2019 | 223 | 2019 |
| dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice G Colasante, G Lignani, S Brusco, C Di Berardino, J Carpenter, ... Molecular Therapy 28 (1), 235-253, 2020 | 213 | 2020 |
| Rapid conversion of fibroblasts into functional forebrain GABAergic interneurons by direct genetic reprogramming G Colasante, G Lignani, A Rubio, L Medrihan, L Yekhlef, A Sessa, ... Cell stem cell 17 (6), 719-734, 2015 | 187 | 2015 |
| Strategies to maximize the performance of a STED microscope S Galiani, B Harke, G Vicidomini, G Lignani, F Benfenati, A Diaspro, ... Optics express 20 (7), 7362-7374, 2012 | 149 | 2012 |
| TAAR1 modulates cortical glutamate NMDA receptor function S Espinoza, G Lignani, L Caffino, S Maggi, I Sukhanov, D Leo, L Mus, ... Neuropsychopharmacology 40 (9), 2217-2227, 2015 | 138 | 2015 |
| In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy G Colasante, Y Qiu, L Massimino, C Di Berardino, JH Cornford, ... Brain 143 (3), 891-905, 2020 | 115 | 2020 |
| REST/NRSF‐mediated intrinsic homeostasis protects neuronal networks from hyperexcitability D Pozzi, G Lignani, E Ferrea, A Contestabile, F Paonessa, ... The EMBO journal 32 (22), 2994-3007, 2013 | 111 | 2013 |
| Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels L Medrihan, F Cesca, A Raimondi, G Lignani, P Baldelli, F Benfenati Nature communications 4 (1), 1512, 2013 | 102 | 2013 |
| Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses AMJ Verstegen, E Tagliatti, G Lignani, A Marte, T Stolero, M Atias, ... Journal of neuroscience 34 (21), 7266-7280, 2014 | 96 | 2014 |
| Trastuzumab in combination with 5‐fluorouracil, leucovorin, oxaliplatin and docetaxel as perioperative treatment for patients with human epidermal growth factor receptor 2 … RD Hofheinz, S Hegewisch‐Becker, V Kunzmann, P Thuss‐Patience, ... International Journal of Cancer 149 (6), 1322-1331, 2021 | 90* | 2021 |
| On-demand cell-autonomous gene therapy for brain circuit disorders Y Qiu, N O’neill, B Maffei, C Zourray, A Almacellas-Barbanoj, ... Science 378 (6619), 523-532, 2022 | 76 | 2022 |
| Synapsins: from synapse to network hyperexcitability and epilepsy A Fassio, A Raimondi, G Lignani, F Benfenati, P Baldelli Seminars in cell & developmental biology 22 (4), 408-415, 2011 | 76 | 2011 |
| Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity G Lignani, A Raimondi, E Ferrea, A Rocchi, F Paonessa, F Cesca, ... Human molecular genetics 22 (11), 2186-2199, 2013 | 68 | 2013 |
| Homeostatic plasticity in epilepsy G Lignani, P Baldelli, V Marra Frontiers in Cellular Neuroscience 14, 197, 2020 | 62 | 2020 |
| Recent advances in gene therapy for neurodevelopmental disorders with epilepsy TJ Turner, C Zourray, S Schorge, G Lignani Journal of neurochemistry 157 (2), 229-262, 2021 | 61 | 2021 |
| Olanzapine: A potent agonist at the hM4D (Gi) DREADD amenable to clinical translation of chemogenetics M Weston, T Kaserer, A Wu, A Mouravlev, JC Carpenter, A Snowball, ... Science Advances 5 (4), eaaw1567, 2019 | 59 | 2019 |
| Gene therapy and editing: Novel potential treatments for neuronal channelopathies RC Wykes, G Lignani Neuropharmacology 132, 108-117, 2018 | 56 | 2018 |
| Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome N Valassina, S Brusco, A Salamone, L Serra, M Luoni, S Giannelli, S Bido, ... Nature communications 13 (1), 161, 2022 | 53 | 2022 |
| Long-term optical stimulation of channelrhodopsin-expressing neurons to study network plasticity G Lignani, E Ferrea, F Difato, J Amarù, E Ferroni, E Lugarà, S Espinoza, ... Frontiers in molecular neuroscience 6, 22, 2013 | 51 | 2013 |
Fabio BenfenatiFull professor of Neurophysiology, University of Genova, Director Center for Synaptic Neuroscience and Technology, Istituto Italiano di TecnologiaDirección de correo verificada de iit.it
