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Joseph A. Tandurella
Joseph A. Tandurella
Graduate Student, University of Pennsylvania
Dirección de correo verificada de pennmedicine.upenn.edu
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Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin
EM Grasset, M Dunworth, G Sharma, M Loth, J Tandurella, ...
Science translational medicine 14 (656), eabn7571, 2022
1092022
Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy
K Li, JA Tandurella, J Gai, Q Zhu, SJ Lim, DL Thomas, T Xia, G Mo, ...
Cancer Cell 40 (11), 1374-1391. e7, 2022
882022
Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial–Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma
S Guinn, B Kinny-Köster, JA Tandurella, JT Mitchell, DN Sidiropoulos, ...
Cancer Research 84 (9), 1517-1533, 2024
14*2024
Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial
ET Roussos Torres, WJ Ho, L Danilova, JA Tandurella, J Leatherman, ...
Nature Cancer, 1-14, 2024
112024
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin. Sci Transl Med. 2022; 14: eabn7571
EM Grasset, M Dunworth, G Sharma, M Loth, J Tandurella, ...
DOI: https://doi. org/10.1126/scitranslmed. abn7571. PMID: https://www. ncbi …, 2023
52023
Entinostat in combination with nivolumab in metastatic pancreatic ductal adenocarcinoma: a phase 2 clinical trial
M Baretti, L Danilova, JN Durham, CB Betts, L Cope, DN Sidiropoulos, ...
Nature communications 15 (1), 9801, 2024
42024
Abstract CT016: Immunomodulation of the tumor microenvironment of pancreatic ductal adenocarcinoma with histone deacetylase inhibition: Results of a phase 2 clinical trial of …
M Baretti, L Danilova, JN Durham, CB Betts, L Cope, DN Sidiropoulos, ...
Cancer Research 84 (7_Supplement), CT016-CT016, 2024
12024
CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial
JM Montagne, JT Mitchell, JA Tandurella, ES Christenson, LV Danilova, ...
iScience 28 (1), 2025
2025
Cancer associated fibroblasts drive epithelial to mesenchymal transition and classical to basal change in pancreatic ductal adenocarcinoma cells with loss of IL-8 expression
S Guinn, B Perez, JA Tandurella, M Ramani, JW Lee, DJ Zabransky, ...
bioRxiv, 2025
2025
Abstract A032: Cancer associated fibroblasts drive classical to basal change associated with increased T cell presence in pancreatic ductal adenocarcinoma
JW Zimmerman, S Guinn, M Ramani, B Perez, JA Tandurella, ...
Cancer Research 84 (17_Supplement_2), A032-A032, 2024
2024
Cancer associated fibroblast-tumor cell crosstalk enhances epithelial to mesenchymal transition and promotes a classical to basal switch in human pancreatic ductal adenocarcinoma
S Guinn, B Perez, J Patel, J Lee, D Zabransky, W Ho, EJ Fertig, E Kartalia, ...
Cancer Research 84 (6_Supplement), 1577-1577, 2024
2024
Abstract A042: Cancer associated fibroblasts drive transcriptional changes in tumor cells from classical to basal phenotype and promote epithelial-to-mesenchymal transition in …
S Guinn, J Tandurella, JW Lee, DJ Zabransky, M Ramani, J Patel, ...
Cancer Research 84 (2_Supplement), A042-A042, 2024
2024
Abstract B034: Antigen-presenting cancer-associated fibroblasts are found in immunotherapy-sensitive murine models of pancreatic ductal adenocarcinoma
S Maru, K Howe, L Andaloori, J Leatherman, J Tandurella, EJ Pearce, ...
Cancer Research 84 (2_Supplement), B034-B034, 2024
2024
Cancer associated fibroblasts drive transcriptional changes in tumor cells from classical to basal phenotype and promote epithelial-to-mesenchymal transition in human …
S Guinn, J Tandurella, JW Lee, DJ Zabransky, M Ramani, J Patel, ...
CANCER RESEARCH 84 (2), 2024
2024
Antigen-presenting cancer-associated fibroblasts are found in immunotherapy-sensitive murine models of pancreatic ductal adenocarcinoma
S Maru, K Howe, L Andaloori, J Leatherman, J Tandurella, EJ Pearce, ...
CANCER RESEARCH 84 (2), 2024
2024
Patient-derived organoid pharmacotyping as a predictive tool for therapeutic selection in pancreatic ductal adenocarcinoma
NG Nicolson, JA Tandurella, LW Wu, J Patel, E Morris, TT Seppälä, ...
Annals of surgery, 10.1097, 2024
2024
Cancer associated fibroblast crosstalk through VEGF increases tumor cell proliferation in human pancreatic ductal adenocarcinoma
S Guinn, J Tandurella, J Patel, R Burkhart, J Zimmerman, E Jaffee
Cancer Research 83 (7_Supplement), 5851-5851, 2023
2023
Single-cell RNA and TCR sequencing of tumor infiltrating lymphocytes identifies changes in pancreatic ductal adenocarcinomas following neoadjuvant treatment with combined anti …
JA Tandurella, JT Mitchell, JM Montagne, E Christenson, Q Zhu, ...
Cancer Research 83 (7_Supplement), 3241-3241, 2023
2023
Cancer associated fibroblasts are regulators of the tumor microenvironment in human pancreatic ductal adenocarcinoma.
S Guinn, J Tandurella, J Zimmerman, R Burkhart, EM Jaffee
CANCER RESEARCH 82 (22), 135-135, 2022
2022
Abstract C036: Cancer associated fibroblasts are regulators of the tumor microenvironment in human pancreatic ductal adenocarcinoma
S Guinn, J Tandurella, J Zimmerman, R Burkhart, EM Jaffee
Cancer Research 82 (22_Supplement), C036-C036, 2022
2022
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