Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin EM Grasset, M Dunworth, G Sharma, M Loth, J Tandurella, ... Science translational medicine 14 (656), eabn7571, 2022 | 109 | 2022 |
Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy K Li, JA Tandurella, J Gai, Q Zhu, SJ Lim, DL Thomas, T Xia, G Mo, ... Cancer Cell 40 (11), 1374-1391. e7, 2022 | 88 | 2022 |
Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial–Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma S Guinn, B Kinny-Köster, JA Tandurella, JT Mitchell, DN Sidiropoulos, ... Cancer Research 84 (9), 1517-1533, 2024 | 14* | 2024 |
Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial ET Roussos Torres, WJ Ho, L Danilova, JA Tandurella, J Leatherman, ... Nature Cancer, 1-14, 2024 | 11 | 2024 |
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin. Sci Transl Med. 2022; 14: eabn7571 EM Grasset, M Dunworth, G Sharma, M Loth, J Tandurella, ... DOI: https://doi. org/10.1126/scitranslmed. abn7571. PMID: https://www. ncbi …, 2023 | 5 | 2023 |
Entinostat in combination with nivolumab in metastatic pancreatic ductal adenocarcinoma: a phase 2 clinical trial M Baretti, L Danilova, JN Durham, CB Betts, L Cope, DN Sidiropoulos, ... Nature communications 15 (1), 9801, 2024 | 4 | 2024 |
Abstract CT016: Immunomodulation of the tumor microenvironment of pancreatic ductal adenocarcinoma with histone deacetylase inhibition: Results of a phase 2 clinical trial of … M Baretti, L Danilova, JN Durham, CB Betts, L Cope, DN Sidiropoulos, ... Cancer Research 84 (7_Supplement), CT016-CT016, 2024 | 1 | 2024 |
CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial JM Montagne, JT Mitchell, JA Tandurella, ES Christenson, LV Danilova, ... iScience 28 (1), 2025 | | 2025 |
Cancer associated fibroblasts drive epithelial to mesenchymal transition and classical to basal change in pancreatic ductal adenocarcinoma cells with loss of IL-8 expression S Guinn, B Perez, JA Tandurella, M Ramani, JW Lee, DJ Zabransky, ... bioRxiv, 2025 | | 2025 |
Abstract A032: Cancer associated fibroblasts drive classical to basal change associated with increased T cell presence in pancreatic ductal adenocarcinoma JW Zimmerman, S Guinn, M Ramani, B Perez, JA Tandurella, ... Cancer Research 84 (17_Supplement_2), A032-A032, 2024 | | 2024 |
Cancer associated fibroblast-tumor cell crosstalk enhances epithelial to mesenchymal transition and promotes a classical to basal switch in human pancreatic ductal adenocarcinoma S Guinn, B Perez, J Patel, J Lee, D Zabransky, W Ho, EJ Fertig, E Kartalia, ... Cancer Research 84 (6_Supplement), 1577-1577, 2024 | | 2024 |
Abstract A042: Cancer associated fibroblasts drive transcriptional changes in tumor cells from classical to basal phenotype and promote epithelial-to-mesenchymal transition in … S Guinn, J Tandurella, JW Lee, DJ Zabransky, M Ramani, J Patel, ... Cancer Research 84 (2_Supplement), A042-A042, 2024 | | 2024 |
Abstract B034: Antigen-presenting cancer-associated fibroblasts are found in immunotherapy-sensitive murine models of pancreatic ductal adenocarcinoma S Maru, K Howe, L Andaloori, J Leatherman, J Tandurella, EJ Pearce, ... Cancer Research 84 (2_Supplement), B034-B034, 2024 | | 2024 |
Cancer associated fibroblasts drive transcriptional changes in tumor cells from classical to basal phenotype and promote epithelial-to-mesenchymal transition in human … S Guinn, J Tandurella, JW Lee, DJ Zabransky, M Ramani, J Patel, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |
Antigen-presenting cancer-associated fibroblasts are found in immunotherapy-sensitive murine models of pancreatic ductal adenocarcinoma S Maru, K Howe, L Andaloori, J Leatherman, J Tandurella, EJ Pearce, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |
Patient-derived organoid pharmacotyping as a predictive tool for therapeutic selection in pancreatic ductal adenocarcinoma NG Nicolson, JA Tandurella, LW Wu, J Patel, E Morris, TT Seppälä, ... Annals of surgery, 10.1097, 2024 | | 2024 |
Cancer associated fibroblast crosstalk through VEGF increases tumor cell proliferation in human pancreatic ductal adenocarcinoma S Guinn, J Tandurella, J Patel, R Burkhart, J Zimmerman, E Jaffee Cancer Research 83 (7_Supplement), 5851-5851, 2023 | | 2023 |
Single-cell RNA and TCR sequencing of tumor infiltrating lymphocytes identifies changes in pancreatic ductal adenocarcinomas following neoadjuvant treatment with combined anti … JA Tandurella, JT Mitchell, JM Montagne, E Christenson, Q Zhu, ... Cancer Research 83 (7_Supplement), 3241-3241, 2023 | | 2023 |
Cancer associated fibroblasts are regulators of the tumor microenvironment in human pancreatic ductal adenocarcinoma. S Guinn, J Tandurella, J Zimmerman, R Burkhart, EM Jaffee CANCER RESEARCH 82 (22), 135-135, 2022 | | 2022 |
Abstract C036: Cancer associated fibroblasts are regulators of the tumor microenvironment in human pancreatic ductal adenocarcinoma S Guinn, J Tandurella, J Zimmerman, R Burkhart, EM Jaffee Cancer Research 82 (22_Supplement), C036-C036, 2022 | | 2022 |