Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3 M Qiu, Z Glass, J Chen, M Haas, X Jin, X Zhao, X Rui, Z Ye, Y Li, F Zhang, ... Proceedings of the National Academy of Sciences 118 (10), e2020401118, 2021 | 319 | 2021 |
Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis M Qiu, Y Tang, J Chen, R Muriph, Z Ye, C Huang, J Evans, EP Henske, ... Proceedings of the national academy of sciences 119 (8), e2116271119, 2022 | 307 | 2022 |
Lipid nanoparticle-mediated lymph node–targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response J Chen, Z Ye, C Huang, M Qiu, D Song, Y Li, Q Xu Proceedings of the National Academy of Sciences 119 (34), e2207841119, 2022 | 294 | 2022 |
Imidazole‐based synthetic lipidoids for in vivo mRNA delivery into primary T lymphocytes X Zhao, J Chen, M Qiu, Y Li, Z Glass, Q Xu Angewandte Chemie International Edition 59 (45), 20083-20089, 2020 | 136 | 2020 |
The effects of protein corona on in vivo fate of nanocarriers Q Xiao, M Zoulikha, M Qiu, C Teng, C Lin, X Li, MA Sallam, Q Xu, W He Advanced Drug Delivery Reviews 186, 114356, 2022 | 132 | 2022 |
Developing biodegradable lipid nanoparticles for intracellular mRNA delivery and genome editing M Qiu, Y Li, H Bloomer, Q Xu Accounts of chemical research 54 (21), 4001-4011, 2021 | 98 | 2021 |
In situ cancer vaccination using lipidoid nanoparticles J Chen, M Qiu, Z Ye, T Nyalile, Y Li, Z Glass, X Zhao, L Yang, J Chen, ... Science advances 7 (19), eabf1244, 2021 | 86 | 2021 |
pH-Responsive Chimaeric Pepsomes Based on Asymmetric Poly(ethylene glycol)-b-Poly(l-leucine)-b-Poly(l-glutamic acid) Triblock Copolymer for Efficient … P Chen, M Qiu, C Deng, F Meng, J Zhang, R Cheng, Z Zhong Biomacromolecules 16 (4), 1322-1330, 2015 | 76 | 2015 |
Polytyrosine nanoparticles enable ultra-high loading of doxorubicin and rapid enzyme-responsive drug release X Gu, M Qiu, H Sun, J Zhang, L Cheng, C Deng, Z Zhong Biomaterials science 6 (6), 1526-1534, 2018 | 62 | 2018 |
Selective cell penetrating peptide‐functionalized envelope‐type chimeric lipopepsomes boost systemic RNAi therapy for lung tumors M Qiu, J Ouyang, Y Wei, J Zhang, Q Lan, C Deng, Z Zhong Advanced Healthcare Materials 8 (16), 1900500, 2019 | 45 | 2019 |
Lipopepsomes: A novel and robust family of nano-vesicles capable of highly efficient encapsulation and tumor-targeted delivery of doxorubicin hydrochloride in vivo M Qiu, H Sun, F Meng, R Cheng, J Zhang, C Deng, Z Zhong Journal of Controlled Release 272, 107-113, 2018 | 45 | 2018 |
Small-sized and robust chimaeric lipopepsomes: a simple and functional platform with high protein loading for targeted intracellular delivery of protein toxin in vivo M Qiu, Z Zhang, Y Wei, H Sun, F Meng, C Deng, Z Zhong Chemistry of Materials 30 (19), 6831-6838, 2018 | 40 | 2018 |
Biodegradable Micelles Based on Poly(ethylene glycol)-b-polylipopeptide Copolymer: A Robust and Versatile Nanoplatform for Anticancer Drug Delivery M Qiu, J Ouyang, H Sun, F Meng, R Cheng, J Zhang, L Cheng, Q Lan, ... ACS Applied Materials & Interfaces 9 (33), 27587-27595, 2017 | 37 | 2017 |
Enhanced protein degradation by intracellular delivery of pre-fused PROTACs using lipid-like nanoparticles J Chen, M Qiu, F Ma, L Yang, Z Glass, Q Xu Journal of Controlled Release 330, 1244-1249, 2021 | 32 | 2021 |
Nonviral nanoparticles for CRISPR-based genome editing: is it just a simple adaption of what have been developed for nucleic acid delivery? M Qiu, Z Glass, Q Xu Biomacromolecules 20 (9), 3333-3339, 2019 | 31 | 2019 |
Reductively cleavable polymer-drug conjugates based on dendritic polyglycerol sulfate and monomethyl auristatin E as anticancer drugs N Rades, K Achazi, M Qiu, C Deng, R Haag, Z Zhong, K Licha Journal of Controlled Release 300, 13-21, 2019 | 31 | 2019 |
cRGD-installed docetaxel-loaded mertansine prodrug micelles: redox-triggered ratiometric dual drug release and targeted synergistic treatment of B16F10 melanoma P Zhong, M Qiu, J Zhang, H Sun, R Cheng, C Deng, F Meng, Z Zhong Nanotechnology 28 (29), 295103, 2017 | 28 | 2017 |
Cyclic RGD-peptide-functionalized polylipopeptide micelles for enhanced loading and targeted delivery of monomethyl auristatin E M Qiu, X Wang, H Sun, J Zhang, C Deng, Z Zhong Molecular Pharmaceutics 15 (11), 4854-4861, 2018 | 22 | 2018 |
Integrated multifunctional micelles co‐self‐assembled from polypeptides conjugated with natural ferulic acid and lipoic acid for doxorubicin delivery T Chen, M Qiu, J Zhang, H Sun, C Deng, Z Zhong ChemPhysChem 19 (16), 2070-2077, 2018 | 17 | 2018 |
Targeted and reduction-sensitive cross-linked PLGA nanotherapeutics for safer and enhanced chemotherapy of malignant melanoma X Wang, M Qiu, C Deng, R Cheng, Z Zhong ACS Biomaterials Science & Engineering 6 (5), 2621-2629, 2019 | 10 | 2019 |