| Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ... Science 348 (6242), 1488-1492, 2015 | 339 | 2015 |
| Expedited mapping of the ligandable proteome using fully functionalized enantiomeric probe pairs Y Wang, MM Dix, G Bianco, JR Remsberg, HY Lee, M Kalocsay, SP Gygi, ... Nature chemistry 11 (12), 1113-1123, 2019 | 138 | 2019 |
| ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth JR Remsberg, RM Suciu, NA Zambetti, TW Hanigan, AJ Firestone, ... Nature chemical biology 17 (8), 856-864, 2021 | 84 | 2021 |
| An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides SM Armour, JR Remsberg, M Damle, S Sidoli, WY Ho, Z Li, BA Garcia, ... Nature communications 8 (1), 1-11, 2017 | 69 | 2017 |
| Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold M Adlanmerini, BJ Carpenter, JR Remsberg, Y Aubert, LC Peed, ... Proceedings of the National Academy of Sciences 116 (37), 18691-18699, 2019 | 61 | 2019 |
| Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion JR Remsberg, BN Ediger, WY Ho, M Damle, Z Li, C Teng, C Lanzillotta, ... Molecular metabolism 6 (1), 30-37, 2017 | 59 | 2017 |
| Proteomic discovery of chemical probes that perturb protein complexes in human cells MR Lazear, JR Remsberg, MG Jaeger, K Rothamel, H Her, KE DeMeester, ... Molecular cell 83 (10), 1725-1742. e12, 2023 | 56 | 2023 |
| Structural analogues of smoothened intracellular loops as potent inhibitors of Hedgehog pathway and cancer cell growth JR Remsberg, H Lou, SG Tarasov, M Dean, NI Tarasova Journal of medicinal chemistry 50 (18), 4534-4538, 2007 | 54 | 2007 |
| Remodeling oncogenic transcriptomes by small molecules targeting NONO SG Kathman, SJ Koo, GL Lindsey, HL Her, SM Blue, H Li, S Jaensch, ... Nature chemical biology 19 (7), 825-836, 2023 | 42 | 2023 |
| A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver Y Shabtai, NK Nagaraj, K Batmanov, YW Cho, Y Guan, C Jiang, ... Genes & Development 35 (5-6), 367-378, 2021 | 31 | 2021 |
| Assigning functionality to cysteines by base editing of cancer dependency genes H Li, T Ma, JR Remsberg, SJ Won, KE DeMeester, E Njomen, ... Nature chemical biology 19 (11), 1320-1330, 2023 | 30 | 2023 |
| Chemical proteomic discovery of isotype‐selective covalent inhibitors of the RNA Methyltransferase NSUN2 Y Tao, JG Felber, Z Zou, E Njomen, JR Remsberg, D Ogasawara, C Ye, ... Angewandte Chemie 135 (51), e202311924, 2023 | 28 | 2023 |
| Peptide Structure Stabilization by Membrane Anchoring and its General Applicability to the Development of Potent Cell‐Permeable Inhibitors L Johannessen, J Remsberg, V Gaponenko, KM Adams, JJ Barchi Jr, ... ChemBioChem 12 (6), 914-921, 2011 | 25 | 2011 |
| Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice NA Zambetti, AJ Firestone, JR Remsberg, BJ Huang, JC Wong, AM Long, ... Blood, The Journal of the American Society of Hematology 135 (20), 1772-1782, 2020 | 24 | 2020 |
| Redirecting the pioneering function of FOXA1 with covalent small molecules SJ Won, Y Zhang, CJ Reinhardt, LM Hargis, NS MacRae, KE DeMeester, ... Molecular Cell 84 (21), 4125-4141. e10, 2024 | 13 | 2024 |
| Proteomic ligandability maps of spirocycle acrylamide stereoprobes identify covalent ERCC3 degraders Z Liu, JR Remsberg, H Li, E Njomen, KE DeMeester, Y Tao, G Xia, ... Journal of the American Chemical Society 146 (15), 10393-10406, 2024 | 13 | 2024 |
| ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth JR Remsberg, RM Suciu, NA Zambetti, TW Hanigan, AJ Firestone, ... bioRxiv, 2020.05. 21.108316, 2020 | 2 | 2020 |
| STEREOSELECTIVE COVALENT LIGANDS FOR ONCOGENIC AND IMMUNOLOGICAL PROTEINS B Cravatt, J Remsberg, M Lazear, M Yokoyama, M Schafroth, ... US Patent App. 18/712,449, 2025 | | 2025 |
| Thyroid Hormone Action in Liver: A Coregulator Shift Rather Than the Canonical Switch Y Shabtai, NK Nagaraj, K Batmanov, YW Cho, Y Guan, C Jiang, ... Journal of the Endocrine Society 5 (Supplement_1), A980-A980, 2021 | | 2021 |
| In vivo evidence validating the palmitoylation/depalmitoylation cycle as a therapeutic target in NRAS mutant hematologic cancers. NA Zambetti, AJ Firestone, JC Wong, AM Long, A Inguva, JR Remsberg, ... MOLECULAR CANCER RESEARCH 18 (5), 44-45, 2020 | | 2020 |