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JR Fraser Cummings
JR Fraser Cummings
Hon. Assocoate Professor, University of Southampton
Dirección de correo verificada de uhs.nhs.uk
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Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
M Parkes, JC Barrett, NJ Prescott, M Tremelling, CA Anderson, SA Fisher, ...
Nature genetics 39 (7), 830-832, 2007
14602007
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ...
The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019
6672019
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
SA Fisher, M Tremelling, CA Anderson, R Gwilliam, S Bumpstead, ...
Nature genetics 40 (6), 710-712, 2008
5602008
The pattern and outcome of acute severe colitis
LC Dinesen, AJ Walsh, MN Protic, G Heap, F Cummings, BF Warren, ...
Journal of Crohn's and Colitis 4 (4), 431-437, 2010
4232010
Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis
P Bowness, A Ridley, J Shaw, AT Chan, I Wong-Baeza, M Fleming, ...
The Journal of Immunology 186 (4), 2672-2680, 2011
3822011
HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease
A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ...
Gastroenterology 158 (1), 189-199, 2020
3622020
IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
M Tremelling, F Cummings, SA Fisher, J Mansfield, R Gwilliam, A Keniry, ...
Gastroenterology 132 (5), 1657-1664, 2007
2792007
Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD
NA Kennedy, S Lin, JR Goodhand, N Chanchlani, B Hamilton, ...
Gut 70 (10), 1884-1893, 2021
2752021
HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
GA Heap, MN Weedon, CM Bewshea, A Singh, M Chen, JB Satchwell, ...
Nature genetics 46 (10), 1131-1134, 2014
2242014
QT and QTc dispersion are accurate predictors of cardiac death in newly diagnosed non-insulin dependent diabetes: cohort study
AAO Naas, NC Davidson, C Thompson, F Cummings, SA Ogston, ...
Bmj 316 (7133), 745-746, 1998
2171998
Biosimilar infliximab in inflammatory bowel disease: outcomes of a managed switching programme
V Razanskaite, M Bettey, L Downey, J Wright, J Callaghan, M Rush, ...
Journal of Crohn's and Colitis 11 (6), 690-696, 2017
1882017
Confirmation of the role of ATG16l1 as a Crohn's disease susceptibility gene
FJR Cummings, R Cooney, S Pathan, CA Anderson, JC Barrett, J Beckly, ...
Inflammatory bowel diseases 13 (8), 941-946, 2007
1612007
Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype
FJR Cummings, T Ahmad, A Geremia, J Beckly, R Cooney, L Hancock, ...
Inflammatory bowel diseases 13 (9), 1063-1068, 2007
1312007
Human intestinal macrophages are involved in the pathology of both ulcerative colitis and Crohn disease
S Dharmasiri, EM Garrido-Martin, RJ Harris, AC Bateman, JE Collins, ...
Inflammatory bowel diseases 27 (10), 1641-1652, 2021
1252021
Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial
C Mowat, I Arnott, A Cahill, M Smith, T Ahmad, S Subramanian, S Travis, ...
The lancet Gastroenterology & hepatology 1 (4), 273-282, 2016
1172016
Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease
GA Heap, K So, M Weedon, N Edney, C Bewshea, A Singh, V Annese, ...
Journal of Crohn's and Colitis 10 (2), 149-158, 2016
1172016
Medical management of Crohn’s disease
JRF Cummings, S Keshav, SPL Travis
Bmj 336 (7652), 1062-1066, 2008
1032008
Oral methotrexate in ulcerative colitis
JRF Cummings, KR Herrlinger, SPL Travis, DA Gorard, AS McIntyre, ...
Alimentary pharmacology & therapeutics 21 (4), 385-389, 2005
982005
The genetics of NOD‐like receptors in Crohn's disease
JRF Cummings, RM Cooney, G Clarke, J Beckly, A Geremia, S Pathan, ...
Tissue antigens 76 (1), 48-56, 2010
902010
Consensus standards of healthcare for adults and children with inflammatory bowel disease in the UK
R Kapasi, J Glatter, CA Lamb, AG Acheson, C Andrews, ID Arnott, ...
Frontline Gastroenterology 11 (3), 178-187, 2020
892020
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