Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates N Wang, X Jiang, S Zhang, A Zhu, Y Yuan, H Xu, J Lei, C Yan Cell 184 (2), 370-383. e13, 2021 | 214 | 2021 |
The conformational dynamics of Cas9 governing DNA cleavage are revealed by single-molecule FRET M Yang, S Peng, R Sun, J Lin, N Wang, C Chen Cell reports 22 (2), 372-382, 2018 | 116 | 2018 |
Structural basis for blocking sugar uptake into the malaria parasite Plasmodium falciparum X Jiang, Y Yuan, J Huang, S Zhang, S Luo, N Wang, D Pu, N Zhao, ... Cell 183 (1), 258-268. e12, 2020 | 61 | 2020 |
Molecular basis for inhibiting human glucose transporters by exofacial inhibitors N Wang, S Zhang, Y Yuan, H Xu, E Defossa, H Matter, M Besenius, ... Nature communications 13 (1), 1-10, 2022 | 28 | 2022 |
Orthosteric–allosteric dual inhibitors of PfHT1 as selective antimalarial agents J Huang, Y Yuan, N Zhao, D Pu, Q Tang, S Zhang, S Luo, X Yang, ... Proceedings of the National Academy of Sciences 118 (3), 2021 | 27 | 2021 |
Structure of the Wnt–Frizzled–LRP6 initiation complex reveals the basis for coreceptor discrimination N Tsutsumi, S Hwang, D Waghray, S Hansen, KM Jude, N Wang, Y Miao, ... Proceedings of the National Academy of Sciences 120 (11), e2218238120, 2023 | 24 | 2023 |
Structural basis of α1A-adrenergic receptor activation and recognition by an extracellular nanobody Y Toyoda, A Zhu, F Kong, S Shan, J Zhao, N Wang, X Sun, L Zhang, ... Nature Communications 14 (1), 3655, 2023 | 21 | 2023 |
Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its … X Peng, N Wang, A Zhu, H Xu, J Li, Y Zhou, C Wang, Q Xiao, L Guo, F Liu, ... PLoS biology 19 (9), e3001386, 2021 | 20 | 2021 |
Regulation of aerobic glycolysis to decelerate tumor proliferation by small molecule inhibitors targeting glucose transporters M Gao, J Huang, X Jiang, Y Yuan, H Pang, S Luo, N Wang, C Yao, Z Lin, ... Protein & cell 11 (6), 446-451, 2020 | 13 | 2020 |
Structure of the interleukin-5 receptor complex exemplifies the organizing principle of common beta cytokine signaling NA Caveney, GE Rodriguez, C Pollmann, T Meyer, MT Borowska, ... Molecular Cell 84 (10), 1995-2005. e7, 2024 | 7 | 2024 |
Structural insights into human MHC-II association with invariant chain N Wang, D Waghray, NA Caveney, KM Jude, KC Garcia Proceedings of the National Academy of Sciences 121 (19), e2403031121, 2024 | 3 | 2024 |
De novo design and structure of a peptide-centric TCR mimic binding module KD Householder, X Xiang, KM Jude, A Deng, M Obenaus, SC Wilson, ... bioRxiv, 2024.12. 16.628822, 2024 | | 2024 |