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xiangjun chen
xiangjun chen
Otros nombresChen Xiangjun, Chen X.J.
Dirección de correo verificada de zju.edu.cn
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Lanosterol reverses protein aggregation in cataracts
L Zhao, XJ Chen, J Zhu, YB Xi, X Yang, LD Hu, H Ouyang, SH Patel, X Jin, ...
Nature 523 (7562), 607-611, 2015
5012015
Molecular genetics of congenital cataracts
J Li, X Chen, Y Yan, K Yao
Experimental Eye Research 191, 107872, 2020
962020
Cataract: advances in surgery and whether surgery remains the only treatment in future
X Chen, J Xu, X Chen, K Yao
Advances in Ophthalmology Practice and Research 1 (1), 100008, 2021
802021
Knockdown of creatine kinase B inhibits ovarian cancer progression by decreasing glycolysis
XH Li, XJ Chen, WB Ou, Q Zhang, ZR Lv, Y Zhan, L Ma, T Huang, YB Yan, ...
The international journal of biochemistry & cell biology 45 (5), 979-986, 2013
712013
Advances in pharmacotherapy of cataracts
J Xu, Q Fu, X Chen, K Yao
Annals of translational medicine 8 (22), 1552, 2020
462020
Lanosterol and 25-hydroxycholesterol dissociate crystallin aggregates isolated from cataractous human lens via different mechanisms
XJ Chen, LD Hu, K Yao, YB Yan
Biochemical and biophysical research communications 506 (4), 868-873, 2018
432018
RNAe: an effective method for targeted protein translation enhancement by artificial non-coding RNA with SINEB2 repeat
Y Yao, S Jin, H Long, Y Yu, Z Zhang, G Cheng, C Xu, Y Ding, Q Guan, ...
Nucleic acids research 43 (9), e58-e58, 2015
412015
ATP can efficiently stabilize protein through a unique mechanism
X Ou, Y Lao, J Xu, Y Wutthinitikornkit, R Shi, X Chen, J Li
JACS Au 1 (10), 1766-1777, 2021
402021
Multiple cytokine analyses of aqueous humor from the patients with retinitis pigmentosa
B Lu, H Yin, Q Tang, W Wang, C Luo, X Chen, X Zhang, K Lai, J Xu, ...
Cytokine 127, 154943, 2020
402020
Effects of cataract-causing mutations W59C and W151C on βB2-crystallin structure, stability and folding
WJ Zhao, J Xu, XJ Chen, HH Liu, K Yao, YB Yan
International Journal of Biological Macromolecules 103, 764-770, 2017
342017
Congenital cataract-causing mutation G129C in γC-crystallin promotes the accumulation of two distinct unfolding intermediates that form highly toxic aggregates
YB Xi, XJ Chen, WJ Zhao, YB Yan
Journal of Molecular Biology 427 (17), 2765-2781, 2015
292015
A new dawn for cataracts
RA Quinlan
Science 350 (6261), 636-637, 2015
282015
DsHsp90 is involved in the early response of Dunaliella salina to environmental stress
SJ Wang, MJ Wu, XJ Chen, Y Jiang, YB Yan
International journal of molecular sciences 13 (7), 7963-7979, 2012
282012
Synthesis, evaluation, and structure–activity relationship study of lanosterol derivatives to reverse mutant-crystallin-induced protein aggregation
X Yang, XJ Chen, Z Yang, YB Xi, L Wang, Y Wu, YB Yan, Y Rao
Journal of Medicinal Chemistry 61 (19), 8693-8706, 2018
262018
The cataract-related S39C variant increases γS-crystallin sensitivity to environmental stress by destroying the intermolecular disulfide cross-links
X Yang, J Xu, C Fu, Z Jia, K Yao, X Chen
Biochemical and Biophysical Research Communications 526 (2), 459-465, 2020
242020
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures
LD Hu, J Wang, XJ Chen, YB Yan
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (2), 118617, 2020
242020
βB2 W151R mutant is prone to degradation, aggregation and exposes the hydrophobic side chains in the fourth Greek Key motif
J Xu, H Wang, A Wang, J Xu, C Fu, Z Jia, K Yao, X Chen
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (2), 166018, 2021
202021
Membrane insertion of αA-crystallin is oligomer-size dependent
HC Tjondro, YB Xi, XJ Chen, JT Su, YB Yan
Biochemical and Biophysical Research Communications 473 (1), 1-7, 2016
202016
Cholesterol metabolism: physiological regulation and diseases
J Guo, S Chen, Y Zhang, J Liu, L Jiang, L Hu, K Yao, Y Yu, X Chen
MedComm 5 (2), e476, 2024
192024
Circulating lipoprotein (a) levels and health outcomes: Phenome-wide Mendelian randomization and disease-trajectory analyses
SC Larsson, L Wang, X Li, F Jiang, X Chen, CS Mantzoros
Metabolism 137, 155347, 2022
182022
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