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John Metzcar
John Metzcar
Post-doctoral Researcher, Therapy Modeling and Development Center, University of Minnesota
Dirección de correo verificada de iu.edu
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A Review of Cell-Based Computational Modeling in Cancer Biology. JCO Clinical Cancer Informatics. 2019;(3): 1–13
J Metzcar, Y Wang, R Heiland, P Macklin
405*
A persistent invasive phenotype in post-hypoxic tumor cells is revealed by fate mapping and computational modeling
HL Rocha, I Godet, F Kurtoglu, J Metzcar, K Konstantinopoulos, S Bhoyar, ...
Iscience 24 (9), 2021
302021
Modeling the extracellular matrix in cell migration and morphogenesis: a guide for the curious biologist
RM Crossley, S Johnson, E Tsingos, Z Bell, M Berardi, M Botticelli, ...
Frontiers in Cell and Developmental Biology 12, 1354132, 2024
212024
A review of mechanistic learning in mathematical oncology
J Metzcar, CR Jutzeler, P Macklin, A Köhn-Luque, SC Brüningk
Frontiers in Immunology 15, 1363144, 2024
152024
Hereditary endocrine tumours: current state-of-the-art and research opportunities: MEN1-related pancreatic NETs: identification of unmet clinical needs and future directives
CR Pieterman, SM Sadowski, JE Maxwell, MH Katz, KE Lines, ...
Endocrine-related cancer 27 (8), 2020
14*2020
Digitize your Biology! Modeling multicellular systems through interpretable cell behavior
JAI Johnson, GL Stein-O’Brien, M Booth, R Heiland, F Kurtoglu, ...
bioRxiv, 2023
92023
A simple framework for agent-based modeling with extracellular matrix
J Metzcar, BS Duggan, B Fischer, M Murphy, R Heiland, P Macklin
BioRxiv, 2022.11. 21.514608, 2024
4*2024
DAPT: A package enabling distributed automated parameter testing
B Duggan, J Metzcar, P Macklin
Gigabyte 2021, 2021
42021
A Review of Cell-Based Computational Modeling in Cancer Biology. JCO Clinical Cancer Informatics 3, 3 (Feb. 2019), 1–13
J Metzcar, Y Wang, R Heiland, P Macklin
22019
A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening
M Botticelli, J Metzcar, T Phillips, S Cox, P Keshavanarayana, F Spill
bioRxiv, 2024.10. 23.619655, 2024
12024
Demystifying the extracellular matrix: A review of current mathematical approaches and recent perspectives
RM Crossley, S Johnson, E Tsingos, Z Bell, M Berardi, M Botticelli, ...
arXiv preprint arXiv:2312.12365, 2023
12023
Improving neuroendocrine tumor treatments with mathematical modeling: lessons from other endocrine cancers
JP Metzcar, R Guenter, Y Wang, K Baker, KE Lines
Endocrine Oncology 1 (aop), 2025
2025
Drug-loaded nanoparticles for cancer therapy: a high-throughput multicellular agent-based modeling study
Y Wang, E Bucher, H Rocha, V Jadhao, J Metzcar, R Heiland, ...
bioRxiv, 2024
2024
Toward a General Framework of Multicellular Systems Biology with Application to Cellular Motility and Phenotype Control
J Metzcar
Indiana University, 2024
2024
Accelerated solving of coupled, non-linear ODEs through LSTM-AI
C Faccini de Lima, J Ferrari Gianlupi, J Metzcar, J Zerick
arXiv e-prints, arXiv: 2009.08278, 2020
2020
Generating Turing-like patterns in an off-lattice agent based model: Handout
B Duggan, J Metzcar
Preprint, 2019
2019
Spatial Pattern Formation in Cell Based Models
B Duggan, J Metzcar
2019
Evaluating a Semi-discrete Approach to Tissue Simulation: Preliminary Results
J Metzcar
Indiana University, 2019
2019
A Review of Cell-Based Computational Modeling in Cancer Biology
MS John Metzcar, MS Yafei Wang, MA Randy Heiland
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