Assembly of allosteric macromolecular switches: lessons from PKA SS Taylor, R Ilouz, P Zhang, AP Kornev Nature reviews Molecular cell biology 13 (10), 646-658, 2012 | 514 | 2012 |
PKA: lessons learned after twenty years SS Taylor, P Zhang, JM Steichen, MM Keshwani, AP Kornev Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1271-1278, 2013 | 332 | 2013 |
Structure and allostery of the PKA RIIβ tetrameric holoenzyme P Zhang, EV Smith-Nguyen, MM Keshwani, MS Deal, AP Kornev, ... Science 335 (6069), 712-716, 2012 | 202 | 2012 |
Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses P Zhang, S Mueller, MC Morais, CM Bator, VD Bowman, S Hafenstein, ... Proceedings of the National Academy of Sciences 105 (47), 18284-18289, 2008 | 109 | 2008 |
The capsid proteins of a large, icosahedral dsDNA virus X Yan, Z Yu, P Zhang, AJ Battisti, HA Holdaway, PR Chipman, C Bajaj, ... Journal of molecular biology 385 (4), 1287-1299, 2009 | 91 | 2009 |
Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding JA Martinez Fiesco, DE Durrant, DK Morrison, P Zhang Nature Communications 13 (1), 486, 2022 | 81 | 2022 |
Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment BR Zhou, KNS Yadav, M Borgnia, J Hong, B Cao, AL Olins, DE Olins, ... Nature communications 10 (1), 2301, 2019 | 68 | 2019 |
Revisit of reconstituted 30-nm nucleosome arrays reveals an ensemble of dynamic structures BR Zhou, J Jiang, R Ghirlando, D Norouzi, KNS Yadav, H Feng, R Wang, ... Journal of molecular biology 430 (18), 3093-3110, 2018 | 54 | 2018 |
An isoform-specific myristylation switch targets type II PKA holoenzymes to membranes P Zhang, F Ye, AC Bastidas, AP Kornev, J Wu, MH Ginsberg, SS Taylor Structure 23 (9), 1563-1572, 2015 | 54 | 2015 |
Single turnover autophosphorylation cycle of the PKA RIIβ holoenzyme P Zhang, MJ Knape, LG Ahuja, MM Keshwani, CC King, M Sastri, ... PLoS biology 13 (7), e1002192, 2015 | 43 | 2015 |
Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP TW Lu, J Wu, PC Aoto, JH Weng, LG Ahuja, N Sun, CY Cheng, P Zhang, ... Proceedings of the National Academy of Sciences 116 (33), 16347-16356, 2019 | 35 | 2019 |
Structures of the PKA RIα holoenzyme with the FLHCC driver J-PKAcα or wild-type PKAcα B Cao, TW Lu, JAM Fiesco, M Tomasini, L Fan, SM Simon, SS Taylor, ... Structure 27 (5), 816-828. e4, 2019 | 34 | 2019 |
Discovery of allostery in PKA signaling P Zhang, AP Kornev, J Wu, SS Taylor Biophysical reviews 7, 227-238, 2015 | 29 | 2015 |
Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in … TW Lu, PC Aoto, JH Weng, C Nielsen, JN Cash, J Hall, P Zhang, ... PLoS Biology 18 (12), e3001018, 2020 | 24 | 2020 |
Cryo-EM reveals unanchored M1-ubiquitin chain binding at hRpn11 of the 26S proteasome X Chen, Z Dorris, D Shi, RK Huang, H Khant, T Fox, N de Val, D Williams, ... Structure 28 (11), 1206-1217. e4, 2020 | 22 | 2020 |
The Roles of the RIIβ Linker and N-terminal Cyclic Nucleotide-binding Domain in Determining the Unique Structures of the Type IIβ Protein Kinase A: A Small Angle X-Ray and … DK Blumenthal, J Copps, EV Smith-Nguyen, P Zhang, WT Heller, ... Journal of Biological Chemistry 289 (41), 28505-28512, 2014 | 10 | 2014 |
Characterization of the New World monkey homologues of human poliovirus receptor CD155 S Khan, X Peng, J Yin, P Zhang, E Wimmer Journal of virology 82 (14), 7167-7179, 2008 | 7 | 2008 |
Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases L Du, BAP Wilson, N Li, R Shah, M Dalilian, D Wang, EA Smith, A Wamiru, ... Journal of Natural Products 86 (10), 2283-2293, 2023 | 4 | 2023 |
Structure and regulation of full-length human leucine-rich repeat kinase 1 RD Metcalfe, JA Martinez Fiesco, L Bonet-Ponce, JH Kluss, MR Cookson, ... Nature Communications 14 (1), 4797, 2023 | 3 | 2023 |
Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3′, 5′-Cyclic Monophosphate-Dependent … BAP Wilson, N Li, JA Martinez Fiesco, M Dalilian, D Wang, EA Smith, ... ACS Pharmacology & Translational Science 6 (4), 633-650, 2023 | 2 | 2023 |