Long‐term expanding human airway organoids for disease modeling N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ... The EMBO journal 38 (4), e100300, 2019 | 919 | 2019 |
High-resolution 3D imaging of fixed and cleared organoids JF Dekkers, M Alieva, LM Wellens, HCR Ariese, PR Jamieson, AM Vonk, ... Nature protocols 14 (6), 1756-1771, 2019 | 470 | 2019 |
CRISPR-based adenine editors correct nonsense mutations in a cystic fibrosis organoid biobank MH Geurts, E de Poel, GD Amatngalim, R Oka, FM Meijers, ... Cell stem cell 26 (4), 503-510. e7, 2020 | 200 | 2020 |
Antimicrobial peptides and innate lung defenses: role in infectious and noninfectious lung diseases and therapeutic applications PS Hiemstra, GD Amatngalim, AM van der Does, C Taube Chest 149 (2), 545-551, 2016 | 135 | 2016 |
Polymeric immunoglobulin receptor down-regulation in chronic obstructive pulmonary disease. Persistence in the cultured epithelium and role of transforming growth factor-β ST Gohy, BR Detry, M Lecocq, C Bouzin, BA Weynand, GD Amatngalim, ... American journal of respiratory and critical care medicine 190 (5), 509-521, 2014 | 120 | 2014 |
TNF-α and IL-1β-activated human mesenchymal stromal cells increase airway epithelial wound healing in vitro via activation of the epidermal growth factor receptor W Broekman, GD Amatngalim, Y de Mooij-Eijk, J Oostendorp, H Roelofs, ... Respiratory Research 17, 1-12, 2016 | 111 | 2016 |
Basal cells contribute to innate immunity of the airway epithelium through production of the antimicrobial protein RNase 7 GD Amatngalim, Y van Wijck, Y de Mooij-Eijk, RM Verhoosel, J Harder, ... The Journal of Immunology 194 (7), 3340-3350, 2015 | 93 | 2015 |
Antibacterial defense of human airway epithelial cells from chronic obstructive pulmonary disease patients induced by acute exposure to nontypeable Haemophilus influenzae … GD Amatngalim, JA Schrumpf, A Henic, E Dronkers, RM Verhoosel, ... Journal of innate immunity 9 (4), 359-374, 2017 | 75 | 2017 |
Aberrant epithelial differentiation by cigarette smoke dysregulates respiratory host defence GD Amatngalim, JA Schrumpf, F Dishchekenian, TCJ Mertens, ... European Respiratory Journal 51 (4), 2018 | 63 | 2018 |
Role of activin-A in cigarette smoke-induced inflammation and COPD FM Verhamme, KR Bracke, GD Amatngalim, GM Verleden, ... European Respiratory Journal 43 (4), 1028-1041, 2014 | 56 | 2014 |
Cathelicidin peptide LL-37 modulates TREM-1 expression and inflammatory responses to microbial compounds GD Amatngalim, A Nijnik, PS Hiemstra, REW Hancock Inflammation 34, 412-425, 2011 | 55 | 2011 |
Proinflammatory cytokines impair vitamin D–induced host defense in cultured airway epithelial cells JA Schrumpf, GD Amatngalim, JB Veldkamp, RM Verhoosel, DK Ninaber, ... American journal of respiratory cell and molecular biology 56 (6), 749-761, 2017 | 53 | 2017 |
Cigarette smoke modulates repair and innate immunity following injury to airway epithelial cells GD Amatngalim, W Broekman, NM Daniel, LEPM van der Vlugt, ... PLoS One 11 (11), e0166255, 2016 | 50 | 2016 |
Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia GD Amatngalim, LW Rodenburg, BL Aalbers, HHM Raeven, EM Aarts, ... Life Science Alliance 5 (12), 2022 | 34 | 2022 |
Airway epithelial cell function and respiratory host defense in chronic obstructive pulmonary disease GD Amatngalim, PS Hiemstra Chinese medical journal 131 (09), 1099-1107, 2018 | 33 | 2018 |
ADAM 17 and EGFR regulate IL‐6 receptor and amphiregulin mRNA expression and release in cigarette smoke‐exposed primary bronchial epithelial cells from patients with chronic … M Stolarczyk, GD Amatngalim, X Yu, M Veltman, PS Hiemstra, BJ Scholte Physiological reports 4 (16), e12878, 2016 | 33 | 2016 |
FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4 K Golebski, W Hoepel, D Van Egmond, EJ De Groot, GD Amatngalim, ... Mucosal immunology 12 (2), 425-433, 2019 | 25 | 2019 |
Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses LEPM van der Vlugt, K Eger, C Müller, DK Ninaber, MC Zarcone, ... Journal of Allergy and Clinical Immunology 141 (5), 1949-1952. e8, 2018 | 23 | 2018 |
Contribution of host defence proteins and peptides to Host-Microbiota interactions in chronic inflammatory lung diseases AM Van der Does, GD Amatngalim, B Keijser, PS Hiemstra, R Villenave Vaccines 6 (3), 49, 2018 | 13 | 2018 |
Drug repurposing for cystic fibrosis: Identification of drugs that induce CFTR-independent fluid secretion in nasal organoids LW Rodenburg, L Delpiano, V Railean, R Centeio, MC Pinto, SMA Smits, ... International Journal of Molecular Sciences 23 (20), 12657, 2022 | 11 | 2022 |