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Dr. Gimano Amatngalim
Dr. Gimano Amatngalim
Assistant Professor, University Medical Center Utrecht
Dirección de correo verificada de umcutrecht.nl - Página principal
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Long‐term expanding human airway organoids for disease modeling
N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ...
The EMBO journal 38 (4), e100300, 2019
9192019
High-resolution 3D imaging of fixed and cleared organoids
JF Dekkers, M Alieva, LM Wellens, HCR Ariese, PR Jamieson, AM Vonk, ...
Nature protocols 14 (6), 1756-1771, 2019
4702019
CRISPR-based adenine editors correct nonsense mutations in a cystic fibrosis organoid biobank
MH Geurts, E de Poel, GD Amatngalim, R Oka, FM Meijers, ...
Cell stem cell 26 (4), 503-510. e7, 2020
2002020
Antimicrobial peptides and innate lung defenses: role in infectious and noninfectious lung diseases and therapeutic applications
PS Hiemstra, GD Amatngalim, AM van der Does, C Taube
Chest 149 (2), 545-551, 2016
1352016
Polymeric immunoglobulin receptor down-regulation in chronic obstructive pulmonary disease. Persistence in the cultured epithelium and role of transforming growth factor-β
ST Gohy, BR Detry, M Lecocq, C Bouzin, BA Weynand, GD Amatngalim, ...
American journal of respiratory and critical care medicine 190 (5), 509-521, 2014
1202014
TNF-α and IL-1β-activated human mesenchymal stromal cells increase airway epithelial wound healing in vitro via activation of the epidermal growth factor receptor
W Broekman, GD Amatngalim, Y de Mooij-Eijk, J Oostendorp, H Roelofs, ...
Respiratory Research 17, 1-12, 2016
1112016
Basal cells contribute to innate immunity of the airway epithelium through production of the antimicrobial protein RNase 7
GD Amatngalim, Y van Wijck, Y de Mooij-Eijk, RM Verhoosel, J Harder, ...
The Journal of Immunology 194 (7), 3340-3350, 2015
932015
Antibacterial defense of human airway epithelial cells from chronic obstructive pulmonary disease patients induced by acute exposure to nontypeable Haemophilus influenzae …
GD Amatngalim, JA Schrumpf, A Henic, E Dronkers, RM Verhoosel, ...
Journal of innate immunity 9 (4), 359-374, 2017
752017
Aberrant epithelial differentiation by cigarette smoke dysregulates respiratory host defence
GD Amatngalim, JA Schrumpf, F Dishchekenian, TCJ Mertens, ...
European Respiratory Journal 51 (4), 2018
632018
Role of activin-A in cigarette smoke-induced inflammation and COPD
FM Verhamme, KR Bracke, GD Amatngalim, GM Verleden, ...
European Respiratory Journal 43 (4), 1028-1041, 2014
562014
Cathelicidin peptide LL-37 modulates TREM-1 expression and inflammatory responses to microbial compounds
GD Amatngalim, A Nijnik, PS Hiemstra, REW Hancock
Inflammation 34, 412-425, 2011
552011
Proinflammatory cytokines impair vitamin D–induced host defense in cultured airway epithelial cells
JA Schrumpf, GD Amatngalim, JB Veldkamp, RM Verhoosel, DK Ninaber, ...
American journal of respiratory cell and molecular biology 56 (6), 749-761, 2017
532017
Cigarette smoke modulates repair and innate immunity following injury to airway epithelial cells
GD Amatngalim, W Broekman, NM Daniel, LEPM van der Vlugt, ...
PLoS One 11 (11), e0166255, 2016
502016
Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia
GD Amatngalim, LW Rodenburg, BL Aalbers, HHM Raeven, EM Aarts, ...
Life Science Alliance 5 (12), 2022
342022
Airway epithelial cell function and respiratory host defense in chronic obstructive pulmonary disease
GD Amatngalim, PS Hiemstra
Chinese medical journal 131 (09), 1099-1107, 2018
332018
ADAM 17 and EGFR regulate IL‐6 receptor and amphiregulin mRNA expression and release in cigarette smoke‐exposed primary bronchial epithelial cells from patients with chronic …
M Stolarczyk, GD Amatngalim, X Yu, M Veltman, PS Hiemstra, BJ Scholte
Physiological reports 4 (16), e12878, 2016
332016
FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4
K Golebski, W Hoepel, D Van Egmond, EJ De Groot, GD Amatngalim, ...
Mucosal immunology 12 (2), 425-433, 2019
252019
Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses
LEPM van der Vlugt, K Eger, C Müller, DK Ninaber, MC Zarcone, ...
Journal of Allergy and Clinical Immunology 141 (5), 1949-1952. e8, 2018
232018
Contribution of host defence proteins and peptides to Host-Microbiota interactions in chronic inflammatory lung diseases
AM Van der Does, GD Amatngalim, B Keijser, PS Hiemstra, R Villenave
Vaccines 6 (3), 49, 2018
132018
Drug repurposing for cystic fibrosis: Identification of drugs that induce CFTR-independent fluid secretion in nasal organoids
LW Rodenburg, L Delpiano, V Railean, R Centeio, MC Pinto, SMA Smits, ...
International Journal of Molecular Sciences 23 (20), 12657, 2022
112022
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