Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system B Zetsche, JS Gootenberg, OO Abudayyeh, IM Slaymaker, KS Makarova, ... Cell 163 (3), 759-771, 2015 | 5153 | 2015 |
Nucleic acid detection with CRISPR-Cas13a/C2c2 JS Gootenberg, OO Abudayyeh, JW Lee, P Essletzbichler, AJ Dy, J Joung, ... Science 356 (6336), 438-442, 2017 | 3293 | 2017 |
RNA targeting with CRISPR–Cas13 OO Abudayyeh, JS Gootenberg, P Essletzbichler, S Han, J Joung, ... Nature 550 (7675), 280-284, 2017 | 2028 | 2017 |
Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28 AA Smargon, DBT Cox, NK Pyzocha, K Zheng, IM Slaymaker, ... Molecular cell 65 (4), 618-630. e7, 2017 | 640 | 2017 |
Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line P Essletzbichler, T Konopka, F Santoro, D Chen, BV Gapp, R Kralovics, ... Genome research 24 (12), 2059-2065, 2014 | 336 | 2014 |
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ... Nature 581 (7808), 316-322, 2020 | 183 | 2020 |
Targeted degradation of SLC transporters reveals amenability of multi-pass transmembrane proteins to ligand-induced proteolysis A Bensimon, MD Pizzagalli, F Kartnig, V Dvorak, P Essletzbichler, ... Cell chemical biology 27 (6), 728-739. e9, 2020 | 88 | 2020 |
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ... Cell host & microbe 23 (6), 766-774. e5, 2018 | 81 | 2018 |
Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells JF da Silva, S Salic, M Wiedner, P Datlinger, P Essletzbichler, A Hanzl, ... Scientific Reports 9 (1), 1-10, 2019 | 21 | 2019 |
A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery P Essletzbichler, V Sedlyarov, F Frommelt, D Soulat, LX Heinz, ... Life Science Alliance 6 (4), 2023 | 1 | 2023 |