| Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance K Natarajan, Y Xie, MR Baer, DD Ross Biochemical pharmacology 83 (8), 1084-1103, 2012 | 501 | 2012 |
| Chemopreventive effects of dietary flaxseed oil on colon tumor development C Dwivedi, K Natarajan, DP Matthees Nutrition and cancer 51 (1), 52-58, 2005 | 131 | 2005 |
| The novel BCR-ABL and FLT3 inhibitor ponatinib is a potent inhibitor of the MDR-associated ATP-binding cassette transporter ABCG2 R Sen, K Natarajan, J Bhullar, S Shukla, HB Fang, L Cai, ZS Chen, ... Molecular cancer therapeutics 11 (9), 2033-2044, 2012 | 104 | 2012 |
| The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent … K Natarajan, J Bhullar, S Shukla, M Burcu, ZS Chen, SV Ambudkar, ... Biochemical pharmacology 85 (4), 514-524, 2013 | 103 | 2013 |
| Pim-1 kinase phosphorylates and stabilizes 130 kDa FLT3 and promotes aberrant STAT5 signaling in acute myeloid leukemia with FLT3 internal tandem duplication K Natarajan, Y Xie, M Burcu, DE Linn, Y Qiu, MR Baer PloS one 8 (9), e74653, 2013 | 75 | 2013 |
| Concurrent inhibition of Pim and FLT3 kinases enhances apoptosis of FLT3-ITD acute myeloid leukemia cells through increased Mcl-1 proteasomal degradation S Kapoor, K Natarajan, PR Baldwin, KA Doshi, RG Lapidus, TJ Mathias, ... Clinical Cancer Research 24 (1), 234-247, 2018 | 41 | 2018 |
| The FLT3 inhibitor quizartinib inhibits ABCG2 at pharmacologically relevant concentrations, with implications for both chemosensitization and adverse drug interactions J Bhullar, K Natarajan, S Shukla, TJ Mathias, M Sadowska, SV Ambudkar, ... PloS one 8 (8), e71266, 2013 | 36 | 2013 |
| The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant … TJ Mathias, K Natarajan, S Shukla, KA Doshi, ZN Singh, SV Ambudkar, ... Investigational new drugs 33, 300-309, 2015 | 29 | 2015 |
| Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress KA Doshi, R Trotta, K Natarajan, FV Rassool, AE Tron, D Huszar, ... Oncotarget 7 (30), 48280, 2016 | 19 | 2016 |
| Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine K Natarajan, Y Xie, T Nakanishi, WT Beck, KS Bauer, DD Ross Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1809 (7), 295-305, 2011 | 19 | 2011 |
| Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway-or androgen withdrawal … Y Xie, T Nakanishi, K Natarajan, L Safren, AW Hamburger, A Hussain, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (3), 317-327, 2015 | 17 | 2015 |
| Antioxidant and protective effects of Amrit Nectar tablets on adriamycin-and cisplatin-induced toxicities C Dwivedi, P Agrawal, K Natarajan, H Sharma Journal of Alternative & Complementary Medicine 11 (1), 143-148, 2005 | 16 | 2005 |
| Role of breast cancer resistance protein (BCRP, ABCG2) in cancer outcomes and drug resistance K Natarajan, MR Baer, DD Ross Resistance to targeted ABC transporters in cancer, 53-88, 2015 | 12 | 2015 |
| Hydroxylated dimeric naphthoquinones increase the generation of reactive oxygen species, induce apoptosis of acute myeloid leukemia cells and are not substrates of the … RG Lapidus, BA Carter-Cooper, M Sadowska, EY Choi, O Wonodi, ... Pharmaceuticals 9 (1), 4, 2016 | 9 | 2016 |
| Toxicokinetic study of recombinant human heparin-binding epidermal growth factor-like growth factor (rhHB-EGF) in female Sprague Dawley rats I Coowanitwong, SK Keay, K Natarajan, TS Garimella, CW Mason, ... Pharmaceutical research 25, 542-550, 2008 | 8 | 2008 |
| Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1 Y Xie, K Natarajan, KS Bauer, T Nakanishi, WT Beck, RS Moreci, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (12 …, 2013 | 6 | 2013 |
| Methods to discover alternative promoter usage and transcriptional regulation of murine Bcrp1 K Natarajan, Y Xie, T Nakanishi, RS Moreci, P Jeyasuria, A Hussain, ... Journal of visualized experiments: JoVE, 53827, 2016 | 3 | 2016 |
| Concurrent inhibition of Pim-1 and FLT3 kinases in FLT3-ITD acute myeloid leukemia post-translationally downregulates the anti-apoptotic protein Mcl-1 through downregulation of … PR Baldwin, S Kapoor, K Natarajan, R Trotta, A Tron, D Huszar, E Davila, ... Blood 128 (22), 35, 2016 | 2 | 2016 |
| The pim kinase inhibitor AZD1208 enhances apoptosis induction by clinically active FLT3 inhibitors in FLT3-ITD acute myeloid leukemia cells in vitro and in vivo through … K Natarajan, TJ Mathias, KA Doshi, AE Tron, M Kraus, R Trotta, D Perrotti, ... Blood 124 (21), 3601, 2014 | 2 | 2014 |
| Chemopreventive effects of alpha-santalol on UVB-induced skin carcinogenesis K Natarajan, HB Valluri, XM Guan, C Dwivedi FASEB JOURNAL 17 (5), A1064-A1064, 2003 | 2 | 2003 |
Zhe-Sheng ChenCollege of Pharmacy and Health Sciences, St. John's UniversityDirección de correo verificada de stjohns.edu
