| The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes W Beumer, SM Gibney, RC Drexhage, L Pont-Lezica, J Doorduin, ... Journal of leukocyte biology 92 (5), 959-975, 2012 | 429 | 2012 |
| Nitric oxide synthase inhibitors have antidepressant-like properties in mice: 1. Acute treatments are active in the forced swim test AJ Harkin, KH Bruce, B Craft, IA Paul European journal of pharmacology 372 (3), 207-213, 1999 | 280 | 1999 |
| Poly I: C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression SM Gibney, B McGuinness, C Prendergast, A Harkin, TJ Connor Brain, behavior, and immunity 28, 170-181, 2013 | 247 | 2013 |
| Induction of indolamine 2, 3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-γ? TJ Connor, N Starr, JB O'Sullivan, A Harkin Neuroscience letters 441 (1), 29-34, 2008 | 246 | 2008 |
| Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism V Gigliucci, G O’Dowd, S Casey, D Egan, S Gibney, A Harkin Psychopharmacology 228, 157-166, 2013 | 204 | 2013 |
| Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test A Harkin, TJ Connor, MP Burns, JP Kelly European Neuropsychopharmacology 14 (4), 274-281, 2004 | 200 | 2004 |
| Gut–brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease Á Abautret-Daly, E Dempsey, A Parra-Blanco, C Medina, A Harkin Acta neuropsychiatrica 30 (5), 275-296, 2018 | 195 | 2018 |
| Stress-related regulation of the kynurenine pathway: Relevance to neuropsychiatric and degenerative disorders K O'Farrell, A Harkin Neuropharmacology 112, 307-323, 2017 | 163 | 2017 |
| Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors A Harkin, TJ Connor, M Walsh, N St John, JP Kelly Neuropharmacology 44 (5), 616-623, 2003 | 160 | 2003 |
| Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration JB O'Sullivan, KM Ryan, NM Curtin, A Harkin, TJ Connor International Journal of Neuropsychopharmacology 12 (5), 687-699, 2009 | 159 | 2009 |
| L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke MI Cuartero, I Ballesteros, J de la Parra, AL Harkin, A Abautret-Daly, ... Circulation 130 (23), 2040-2051, 2014 | 146 | 2014 |
| Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test TJ Connor, P Kelliher, Y Shen, A Harkin, JP Kelly, BE Leonard Pharmacology Biochemistry and Behavior 65 (4), 591-597, 2000 | 145 | 2000 |
| Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression A Harkin, JP Kelly, M McNamara, TJ Connor, K Dredge, A Redmond, ... European journal of pharmacology 364 (2-3), 123-132, 1999 | 142 | 1999 |
| Acute stress suppresses pro-inflammatory cytokines TNF-α and IL-1β independent of a catecholamine-driven increase in IL-10 production TJ Connor, C Brewer, JP Kelly, A Harkin Journal of neuroimmunology 159 (1-2), 119-128, 2005 | 138 | 2005 |
| A review of the relevance and validity of olfactory bulbectomy as a model of depression A Harkin, JP Kelly, BE Leonard Clinical Neuroscience Research 3 (4-5), 253-262, 2003 | 131 | 2003 |
| DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic–pituitary–adrenal axis activity and to early … C Farrell, K Doolin, N O’Leary, C Jairaj, D Roddy, L Tozzi, D Morris, ... Psychiatry research 265, 341-348, 2018 | 126 | 2018 |
| Olfactory bulbectomy in mice induces alterations in exploratory behavior M Zueger, A Urani, S Chourbaji, C Zacher, M Roche, A Harkin, P Gass Neuroscience letters 374 (2), 142-146, 2005 | 122 | 2005 |
| Varying responses to the rat forced-swim test under diurnal and nocturnal conditions P Kelliher, TJ Connor, A Harkin, C Sanchez, JP Kelly, BE Leonard Physiology & behavior 69 (4-5), 531-539, 2000 | 120 | 2000 |
| Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation MM Hughes, A Carballedo, DM McLoughlin, F Amico, A Harkin, T Frodl, ... Brain, behavior, and immunity 26 (6), 979-987, 2012 | 119 | 2012 |
| C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy MM Pertl, D Hevey, NT Boyle, MM Hughes, S Collier, AM O’Dwyer, ... Brain, behavior, and immunity 34, 108-119, 2013 | 111 | 2013 |
