| Discriminative accuracy of plasma phospho-tau217 for Alzheimer disease vs other neurodegenerative disorders S Palmqvist, S Janelidze, YT Quiroz, H Zetterberg, F Lopera, E Stomrud, ... Jama 324 (8), 772-781, 2020 | 1050 | 2020 |
| Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia S Janelidze, N Mattsson, S Palmqvist, R Smith, TG Beach, GE Serrano, ... Nature medicine 26 (3), 379-386, 2020 | 1024 | 2020 |
| Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration EH Thijssen, R La Joie, A Wolf, A Strom, P Wang, L Iaccarino, ... Nature medicine 26 (3), 387-397, 2020 | 639 | 2020 |
| Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau-and amyloid-positron emission tomography MM Mielke, CE Hagen, J Xu, X Chai, P Vemuri, VJ Lowe, DC Airey, ... Alzheimer's & Dementia 14 (8), 989-997, 2018 | 562 | 2018 |
| Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression X Chai, S Wu, TK Murray, R Kinley, CV Cella, H Sims, N Buckner, ... Journal of Biological Chemistry 286 (39), 34457-34467, 2011 | 411 | 2011 |
| Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer’s disease S Janelidze, E Stomrud, R Smith, S Palmqvist, N Mattsson, DC Airey, ... Nature communications 11 (1), 1683, 2020 | 391 | 2020 |
| Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease S Palmqvist, PS Insel, E Stomrud, S Janelidze, H Zetterberg, B Brix, ... EMBO molecular medicine 11 (12), e11170, 2019 | 306 | 2019 |
| Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer’s disease N Mattsson-Carlgren, E Andersson, S Janelidze, R Ossenkoppele, P Insel, ... Science advances 6 (16), eaaz2387, 2020 | 288 | 2020 |
| Constitutive secretion of tau protein by an unconventional mechanism X Chai, JL Dage, M Citron Neurobiology of disease 48 (3), 356-366, 2012 | 267 | 2012 |
| Cloning of a cDNA for Liver Microsomal Retinol Dehydrogenase: A TISSUE-SPECIFIC, SHORT-CHAIN ALCOHOL DEHYDROGENASE (∗) X Chai, MHEM Boerman, Y Zhai, JL Napoli Journal of Biological Chemistry 270 (8), 3900-3904, 1995 | 173 | 1995 |
| Cloning of a cDNA for a second retinol dehydrogenase type II: expression of its mRNA relative to type I X Chai, Y Zhai, G Popescu, JL Napoli Journal of Biological Chemistry 270 (47), 28408-28412, 1995 | 125 | 1995 |
| Enzymes and binding proteins affecting retinoic acid concentrations JL Napoli, M Boerman, X Chai, Y Zhai, PD Fiorella The Journal of steroid biochemistry and molecular biology 53 (1-6), 497-502, 1995 | 123 | 1995 |
| Activity of human 11-cis-retinol dehydrogenase (Rdh5) with steroids and retinoids and expression of its mRNA in extra-ocular human tissue J Wang, X CHAI, U ERIKSSON, JL NAPOLI Biochemical Journal 338 (1), 23-27, 1999 | 112 | 1999 |
| cDNA cloning and characterization of a cis-retinol/3α-hydroxysterol short-chain dehydrogenase X Chai, Y Zhai, JL Napoli Journal of Biological Chemistry 272 (52), 33125-33131, 1997 | 108 | 1997 |
| Cloning of a rat cDNA encoding retinol dehydrogenase isozyme type III X Chai, Y Zhai, JL Napoli Gene 169 (2), 219-222, 1996 | 89 | 1996 |
| cDNA cloning, tissue distribution, and substrate characteristics of a cis-retinol/3α-hydroxysterol short-chain dehydrogenase isozyme J Su, X Chai, B Kahn, JL Napoli Journal of Biological Chemistry 273 (28), 17910-17916, 1998 | 88 | 1998 |
| Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) investigators. Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and … EH Thijssen, R La Joie, A Wolf, A Strom, P Wang, L Iaccarino, ... Nat Med 26 (3), 387-397, 2020 | 75 | 2020 |
| Biochemical and kinetic characterization of BACE1: investigation into the putative species‐specificity for β‐and β′‐cleavage sites by human and murine BACE1 HC Yang, X Chai, M Mosior, W Kohn, LN Boggs, JA Erickson, DB McClure, ... Journal of neurochemistry 91 (6), 1249-1259, 2004 | 22 | 2004 |
| Structure, promoter and chromosomal localization of rdh6 X Chai, W Chen, JL Napoli Gene 274 (1-2), 27-33, 2001 | 9 | 2001 |
| Phospho‐tau217 and phospho‐tau181 in plasma and CSF as biomarkers for Alzheimer’s disease: Clinical study results of AD blood biomarkers S Janelidze, S Palmqvist, YT Quiroz, F Lopera, E Stomrud, Y Su, Y Chen, ... Alzheimer's & Dementia 16, e037520, 2020 | 6 | 2020 |
