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Salim Megat
Salim Megat
University of Strasbourg - INSERM U1118
Dirección de correo verificada de inserm.fr
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The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain
JK Moy, A Khoutorsky, MN Asiedu, BJ Black, JL Kuhn, ...
Journal of Neuroscience 37 (31), 7481-7499, 2017
1452017
Nociceptor translational profiling reveals the Ragulator-Rag GTPase complex as a critical generator of neuropathic pain
S Megat, PR Ray, JK Moy, TF Lou, P Barragán-Iglesias, Y Li, G Pradhan, ...
Journal of Neuroscience 39 (3), 393-411, 2019
1192019
The sciatic nerve cuffing model of neuropathic pain in mice
I Yalcin, S Megat, F Barthas, E Waltisperger, M Kremer, E Salvat, M Barrot
Journal of visualized experiments: JoVE, 51608, 2014
1092014
A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline
M Kremer, I Yalcin, Y Goumon, X Wurtz, L Nexon, D Daniel, S Megat, ...
Journal of Neuroscience 38 (46), 9934-9954, 2018
1032018
Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling
S Megat, PR Ray, D Tavares-Ferreira, JK Moy, I Sankaranarayanan, ...
Journal of Neuroscience 39 (35), 6829-6847, 2019
912019
A critical role for dopamine D5 receptors in pain chronicity in male mice
S Megat, S Shiers, JK Moy, P Barragan-Iglesias, G Pradhan, RP Seal, ...
Journal of Neuroscience 38 (2), 379-397, 2018
912018
Antidepressants suppress neuropathic pain by a peripheral β2-adrenoceptor mediated anti-TNFα mechanism
Y Bohren, LH Tessier, S Megat, H Petitjean, S Hugel, D Daniel, M Kremer, ...
Neurobiology of disease 60, 39-50, 2013
802013
Inhibition of Poly (A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice
P Barragan-Iglesias, TF Lou, VD Bhat, S Megat, MD Burton, TJ Price, ...
Nature communications 9 (1), 10, 2018
662018
Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS
S Sahadevan, KM Hembach, E Tantardini, M Pérez-Berlanga, ...
Nature communications 12 (1), 3027, 2021
652021
Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice
D Tavares-Ferreira, PR Ray, I Sankaranarayanan, GL Mejia, A Wangzhou, ...
Biological psychiatry 91 (1), 129-140, 2022
582022
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects
J Scekic-Zahirovic, I Sanjuan-Ruiz, V Kan, S Megat, P De Rossi, ...
Nature Communications 12 (1), 3028, 2021
502021
Temporal and sex differences in the role of BDNF/TrkB signaling in hyperalgesic priming in mice and rats
JK Moy, T Szabo-Pardi, DV Tillu, S Megat, G Pradhan, M Kume, ...
Neurobiology of Pain 5, 100024, 2019
452019
Neuroligin 2 regulates spinal GABAergic plasticity in hyperalgesic priming, a model of the transition from acute to chronic pain
JYV Kim, S Megat, JK Moy, MN Asiedu, GL Mejia, J Vagner, TJ Price
Pain 157 (6), 1314-1324, 2016
372016
Integrative genetic analysis illuminates ALS heritability and identifies risk genes
S Megat, N Mora, J Sanogo, O Roman, A Catanese, NO Alami, ...
Nature communications 14 (1), 342, 2023
292023
Therapeutic opportunities for pain medicines via targeting of specific translation signaling mechanisms
S Megat, TJ Price
Neurobiology of Pain 4, 8-19, 2018
242018
Intercellular arc signaling regulates vasodilation
JB de la Peña, P Barragan-Iglesias, TF Lou, N Kunder, S Loerch, ...
Journal of Neuroscience 41 (37), 7712-7726, 2021
222021
Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model
M Bollenbach, C Lugnier, M Kremer, E Salvat, S Megat, F Bihel, ...
European Journal of Medicinal Chemistry 177, 269-290, 2019
222019
Sex differences in the role of atypical PKC within the basolateral nucleus of the amygdala in a mouse hyperalgesic priming model
D Baptista-de-Souza, D Tavares-Ferreira, S Megat, I Sankaranarayanan, ...
Neurobiology of Pain 8, 100049, 2020
202020
κ‐opioid receptors are not necessary for the antidepressant treatment of neuropathic pain
S Megat, Y Bohren, S Doridot, C Gaveriaux‐Ruff, BL Kieffer, ...
British journal of pharmacology 172 (4), 1034-1044, 2015
162015
Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation
I Sanjuan-Ruiz, N Govea-Perez, M McAlonis-Downes, S Dieterle, S Megat, ...
Molecular neurodegeneration 16, 1-14, 2021
132021
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Artículos 1–20