The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain JK Moy, A Khoutorsky, MN Asiedu, BJ Black, JL Kuhn, ... Journal of Neuroscience 37 (31), 7481-7499, 2017 | 145 | 2017 |
Nociceptor translational profiling reveals the Ragulator-Rag GTPase complex as a critical generator of neuropathic pain S Megat, PR Ray, JK Moy, TF Lou, P Barragán-Iglesias, Y Li, G Pradhan, ... Journal of Neuroscience 39 (3), 393-411, 2019 | 119 | 2019 |
The sciatic nerve cuffing model of neuropathic pain in mice I Yalcin, S Megat, F Barthas, E Waltisperger, M Kremer, E Salvat, M Barrot Journal of visualized experiments: JoVE, 51608, 2014 | 109 | 2014 |
A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline M Kremer, I Yalcin, Y Goumon, X Wurtz, L Nexon, D Daniel, S Megat, ... Journal of Neuroscience 38 (46), 9934-9954, 2018 | 103 | 2018 |
Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling S Megat, PR Ray, D Tavares-Ferreira, JK Moy, I Sankaranarayanan, ... Journal of Neuroscience 39 (35), 6829-6847, 2019 | 91 | 2019 |
A critical role for dopamine D5 receptors in pain chronicity in male mice S Megat, S Shiers, JK Moy, P Barragan-Iglesias, G Pradhan, RP Seal, ... Journal of Neuroscience 38 (2), 379-397, 2018 | 91 | 2018 |
Antidepressants suppress neuropathic pain by a peripheral β2-adrenoceptor mediated anti-TNFα mechanism Y Bohren, LH Tessier, S Megat, H Petitjean, S Hugel, D Daniel, M Kremer, ... Neurobiology of disease 60, 39-50, 2013 | 80 | 2013 |
Inhibition of Poly (A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice P Barragan-Iglesias, TF Lou, VD Bhat, S Megat, MD Burton, TJ Price, ... Nature communications 9 (1), 10, 2018 | 66 | 2018 |
Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS S Sahadevan, KM Hembach, E Tantardini, M Pérez-Berlanga, ... Nature communications 12 (1), 3027, 2021 | 65 | 2021 |
Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice D Tavares-Ferreira, PR Ray, I Sankaranarayanan, GL Mejia, A Wangzhou, ... Biological psychiatry 91 (1), 129-140, 2022 | 58 | 2022 |
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects J Scekic-Zahirovic, I Sanjuan-Ruiz, V Kan, S Megat, P De Rossi, ... Nature Communications 12 (1), 3028, 2021 | 50 | 2021 |
Temporal and sex differences in the role of BDNF/TrkB signaling in hyperalgesic priming in mice and rats JK Moy, T Szabo-Pardi, DV Tillu, S Megat, G Pradhan, M Kume, ... Neurobiology of Pain 5, 100024, 2019 | 45 | 2019 |
Neuroligin 2 regulates spinal GABAergic plasticity in hyperalgesic priming, a model of the transition from acute to chronic pain JYV Kim, S Megat, JK Moy, MN Asiedu, GL Mejia, J Vagner, TJ Price Pain 157 (6), 1314-1324, 2016 | 37 | 2016 |
Integrative genetic analysis illuminates ALS heritability and identifies risk genes S Megat, N Mora, J Sanogo, O Roman, A Catanese, NO Alami, ... Nature communications 14 (1), 342, 2023 | 29 | 2023 |
Therapeutic opportunities for pain medicines via targeting of specific translation signaling mechanisms S Megat, TJ Price Neurobiology of Pain 4, 8-19, 2018 | 24 | 2018 |
Intercellular arc signaling regulates vasodilation JB de la Peña, P Barragan-Iglesias, TF Lou, N Kunder, S Loerch, ... Journal of Neuroscience 41 (37), 7712-7726, 2021 | 22 | 2021 |
Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model M Bollenbach, C Lugnier, M Kremer, E Salvat, S Megat, F Bihel, ... European Journal of Medicinal Chemistry 177, 269-290, 2019 | 22 | 2019 |
Sex differences in the role of atypical PKC within the basolateral nucleus of the amygdala in a mouse hyperalgesic priming model D Baptista-de-Souza, D Tavares-Ferreira, S Megat, I Sankaranarayanan, ... Neurobiology of Pain 8, 100049, 2020 | 20 | 2020 |
κ‐opioid receptors are not necessary for the antidepressant treatment of neuropathic pain S Megat, Y Bohren, S Doridot, C Gaveriaux‐Ruff, BL Kieffer, ... British journal of pharmacology 172 (4), 1034-1044, 2015 | 16 | 2015 |
Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation I Sanjuan-Ruiz, N Govea-Perez, M McAlonis-Downes, S Dieterle, S Megat, ... Molecular neurodegeneration 16, 1-14, 2021 | 13 | 2021 |