| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6308 | 2018 |
| Regulation of cancer cell metabolism RA Cairns, IS Harris, TW Mak Nature Reviews Cancer 11 (2), 85-95, 2011 | 5691 | 2011 |
| Modulation of oxidative stress as an anticancer strategy C Gorrini, IS Harris, TW Mak Nature reviews Drug discovery 12 (12), 931-947, 2013 | 3619 | 2013 |
| Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ... Cancer cell 27 (2), 211-222, 2015 | 1011 | 2015 |
| IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ... Nature 488 (7413), 656-659, 2012 | 629 | 2012 |
| The complex interplay between antioxidants and ROS in cancer IS Harris, GM DeNicola Trends in cell biology 30 (6), 440-451, 2020 | 556 | 2020 |
| Glutathione primes T cell metabolism for inflammation TW Mak, M Grusdat, GS Duncan, C Dostert, Y Nonnenmacher, M Cox, ... Immunity 46 (4), 675-689, 2017 | 496 | 2017 |
| D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function M Sasaki, CB Knobbe, M Itsumi, AJ Elia, IS Harris, IIC Chio, RA Cairns, ... Genes & development 26 (18), 2038-2049, 2012 | 364 | 2012 |
| BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival C Gorrini, PS Baniasadi, IS Harris, J Silvester, S Inoue, B Snow, PA Joshi, ... Journal of Experimental Medicine 210 (8), 1529-1544, 2013 | 325 | 2013 |
| FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2 WJ Bakker, IS Harris, TW Mak Molecular cell 28 (6), 941-953, 2007 | 321 | 2007 |
| Differential glutamate metabolism in proliferating and quiescent mammary epithelial cells JL Coloff, JP Murphy, CR Braun, IS Harris, LM Shelton, K Kami, SP Gygi, ... Cell metabolism 23 (5), 867-880, 2016 | 290 | 2016 |
| Non-canonical glutamate-cysteine ligase activity protects against ferroptosis YP Kang, A Mockabee-Macias, C Jiang, A Falzone, N Prieto-Farigua, ... Cell metabolism 33 (1), 174-189. e7, 2021 | 261 | 2021 |
| Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance N Takahashi, HY Chen, IS Harris, DG Stover, LM Selfors, RT Bronson, ... Cancer cell 33 (6), 985-1003. e7, 2018 | 238 | 2018 |
| Cancer cell metabolism RA Cairns, I Harris, S McCracken, TW Mak Cold Spring Harbor symposia on quantitative biology 76, 299-311, 2011 | 210 | 2011 |
| Global proteomic assessment of the classical protein-tyrosine phosphatome and “Redoxome” R Karisch, M Fernandez, P Taylor, C Virtanen, JR St-Germain, LL Jin, ... Cell 146 (5), 826-840, 2011 | 181 | 2011 |
| Glutathione restricts serine metabolism to preserve regulatory T cell function H Kurniawan, DG Franchina, L Guerra, L Bonetti, L Soriano-Baguet, ... Cell metabolism 31 (5), 920-936. e7, 2020 | 160 | 2020 |
| Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer S Shu, HJ Wu, YG Jennifer, R Zeid, IS Harris, B Jovanović, K Murphy, ... Molecular cell 78 (6), 1096-1113. e8, 2020 | 157 | 2020 |
| Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 S Inoue, Z Hao, AJ Elia, D Cescon, L Zhou, J Silvester, B Snow, IS Harris, ... Genes & development 27 (10), 1101-1114, 2013 | 157 | 2013 |
| Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ... Cell metabolism 29 (5), 1166-1181. e6, 2019 | 146 | 2019 |
| 3D culture models with CRISPR screens reveal hyperactive NRF2 as a prerequisite for spheroid formation via regulation of proliferation and ferroptosis N Takahashi, P Cho, LM Selfors, HJ Kuiken, R Kaul, T Fujiwara, IS Harris, ... Molecular cell 80 (5), 828-844. e6, 2020 | 145 | 2020 |
Anne BrustleAustralian National UniversityDirección de correo verificada de anu.edu.au