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Tiziana Borsello
Tiziana Borsello
Professore Ordinario
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A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
T Borsello, PGH Clarke, L Hirt, A Vercelli, M Repici, DF Schorderet, ...
Nature medicine 9 (9), 1180-1186, 2003
8372003
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein
C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ...
Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010
6102010
A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and …
ZY Zhuang, YR Wen, DR Zhang, T Borsello, C Bonny, GR Strichartz, ...
Journal of Neuroscience 26 (13), 3551-3560, 2006
5962006
JNK signalling: a possible target to prevent neurodegeneration
T Borsello, G Forloni
Current pharmaceutical design 13 (18), 1875-1886, 2007
2902007
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo
BR Fluharty, E Biasini, M Stravalaci, A Sclip, L Diomede, C Balducci, ...
Journal of Biological Chemistry 288 (11), 7857-7866, 2013
2222013
Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure
S Abdelli, J Ansite, R Roduit, T Borsello, I Matsumoto, T Sawada, ...
Diabetes 53 (11), 2815-2823, 2004
2162004
N‐methyl‐d‐aspartate‐triggered neuronal death in organotypic hippocampal cultures is endocytic, autophagic and mediated by the c‐Jun N‐terminal kinase …
T Borsello, K Croquelois, JP Hornung, PGH Clarke
European Journal of Neuroscience 18 (3), 473-485, 2003
2072003
JNK regulates APP cleavage and degradation in a model of Alzheimer's disease
A Colombo, A Bastone, C Ploia, A Sclip, M Salmona, G Forloni, T Borsello
Neurobiology of disease 33 (3), 518-525, 2009
1812009
JNK plays a key role in tau hyperphosphorylation in Alzheimer's disease models
C Ploia, X Antoniou, A Sclip, V Grande, D Cardinetti, A Colombo, N Canu, ...
Journal of Alzheimer's Disease 26 (2), 315-329, 2011
1542011
Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons
C Centeno, M Repici, JY Chatton, BM Riederer, C Bonny, P Nicod, ...
Cell Death & Differentiation 14 (2), 240-253, 2007
1542007
c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo
A Sclip, A Tozzi, A Abaza, D Cardinetti, I Colombo, P Calabresi, ...
Cell death & disease 5 (1), e1019-e1019, 2014
1252014
JNK3 as a therapeutic target for neurodegenerative diseases
X Antoniou, M Falconi, D Di Marino, T Borsello
Journal of Alzheimer's Disease 24 (4), 633-642, 2011
1032011
c-Jun N-terminal kinase regulates soluble Aβ oligomers and cognitive impairment in AD mouse model
A Sclip, X Antoniou, A Colombo, GG Camici, L Pozzi, D Cardinetti, ...
Journal of Biological Chemistry 286 (51), 43871-43880, 2011
1002011
Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation
M Repici, C Centeno, S Tomasi, G Forloni, C Bonny, A Vercelli, T Borsello
Neuroscience 150 (1), 40-49, 2007
992007
Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer’s disease
R Epis, E Marcello, F Gardoni, C Vastagh, M Malinverno, C Balducci, ...
Brain 133 (11), 3323-3335, 2010
932010
Regressive modifications of climbing fibres following Purkinje cell degeneration in the cerebellar cortex of the adult rat
F Rossi, T Borsello, E Vaudano, P Strata
Neuroscience 53 (3), 759-778, 1993
751993
Use of cell-permeable peptides to prevent neuronal degeneration
T Borsello, C Bonny
Trends in Molecular Medicine 10 (5), 239-244, 2004
742004
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline
K Little, M Llorián-Salvador, S Scullion, C Hernández, O Simó-Servat, ...
Trends in Endocrinology & Metabolism 33 (1), 50-71, 2022
702022
Targeting the JNK pathway as a therapeutic protective strategy for nervous system diseases
C Bonny, T Borsello, A Zine
Reviews in the Neurosciences 16 (1), 57-68, 2005
642005
Crosstalk between JNK and SUMO Signaling Pathways: deSUMOylation Is Protective against H2O2-Induced Cell Injury
M Feligioni, E Brambilla, A Camassa, A Sclip, A Arnaboldi, F Morelli, ...
PloS one 6 (12), e28185, 2011
602011
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