A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia T Borsello, PGH Clarke, L Hirt, A Vercelli, M Repici, DF Schorderet, ... Nature medicine 9 (9), 1180-1186, 2003 | 837 | 2003 |
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ... Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010 | 610 | 2010 |
A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and … ZY Zhuang, YR Wen, DR Zhang, T Borsello, C Bonny, GR Strichartz, ... Journal of Neuroscience 26 (13), 3551-3560, 2006 | 596 | 2006 |
JNK signalling: a possible target to prevent neurodegeneration T Borsello, G Forloni Current pharmaceutical design 13 (18), 1875-1886, 2007 | 290 | 2007 |
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo BR Fluharty, E Biasini, M Stravalaci, A Sclip, L Diomede, C Balducci, ... Journal of Biological Chemistry 288 (11), 7857-7866, 2013 | 222 | 2013 |
Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure S Abdelli, J Ansite, R Roduit, T Borsello, I Matsumoto, T Sawada, ... Diabetes 53 (11), 2815-2823, 2004 | 216 | 2004 |
N‐methyl‐d‐aspartate‐triggered neuronal death in organotypic hippocampal cultures is endocytic, autophagic and mediated by the c‐Jun N‐terminal kinase … T Borsello, K Croquelois, JP Hornung, PGH Clarke European Journal of Neuroscience 18 (3), 473-485, 2003 | 207 | 2003 |
JNK regulates APP cleavage and degradation in a model of Alzheimer's disease A Colombo, A Bastone, C Ploia, A Sclip, M Salmona, G Forloni, T Borsello Neurobiology of disease 33 (3), 518-525, 2009 | 181 | 2009 |
JNK plays a key role in tau hyperphosphorylation in Alzheimer's disease models C Ploia, X Antoniou, A Sclip, V Grande, D Cardinetti, A Colombo, N Canu, ... Journal of Alzheimer's Disease 26 (2), 315-329, 2011 | 154 | 2011 |
Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons C Centeno, M Repici, JY Chatton, BM Riederer, C Bonny, P Nicod, ... Cell Death & Differentiation 14 (2), 240-253, 2007 | 154 | 2007 |
c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo A Sclip, A Tozzi, A Abaza, D Cardinetti, I Colombo, P Calabresi, ... Cell death & disease 5 (1), e1019-e1019, 2014 | 125 | 2014 |
JNK3 as a therapeutic target for neurodegenerative diseases X Antoniou, M Falconi, D Di Marino, T Borsello Journal of Alzheimer's Disease 24 (4), 633-642, 2011 | 103 | 2011 |
c-Jun N-terminal kinase regulates soluble Aβ oligomers and cognitive impairment in AD mouse model A Sclip, X Antoniou, A Colombo, GG Camici, L Pozzi, D Cardinetti, ... Journal of Biological Chemistry 286 (51), 43871-43880, 2011 | 100 | 2011 |
Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation M Repici, C Centeno, S Tomasi, G Forloni, C Bonny, A Vercelli, T Borsello Neuroscience 150 (1), 40-49, 2007 | 99 | 2007 |
Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer’s disease R Epis, E Marcello, F Gardoni, C Vastagh, M Malinverno, C Balducci, ... Brain 133 (11), 3323-3335, 2010 | 93 | 2010 |
Regressive modifications of climbing fibres following Purkinje cell degeneration in the cerebellar cortex of the adult rat F Rossi, T Borsello, E Vaudano, P Strata Neuroscience 53 (3), 759-778, 1993 | 75 | 1993 |
Use of cell-permeable peptides to prevent neuronal degeneration T Borsello, C Bonny Trends in Molecular Medicine 10 (5), 239-244, 2004 | 74 | 2004 |
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline K Little, M Llorián-Salvador, S Scullion, C Hernández, O Simó-Servat, ... Trends in Endocrinology & Metabolism 33 (1), 50-71, 2022 | 70 | 2022 |
Targeting the JNK pathway as a therapeutic protective strategy for nervous system diseases C Bonny, T Borsello, A Zine Reviews in the Neurosciences 16 (1), 57-68, 2005 | 64 | 2005 |
Crosstalk between JNK and SUMO Signaling Pathways: deSUMOylation Is Protective against H2O2-Induced Cell Injury M Feligioni, E Brambilla, A Camassa, A Sclip, A Arnaboldi, F Morelli, ... PloS one 6 (12), e28185, 2011 | 60 | 2011 |