Atomic view of a toxic amyloid small oligomer A Laganowsky, C Liu, MR Sawaya, JP Whitelegge, J Park, M Zhao, ... Science 335 (6073), 1228-1231, 2012 | 621 | 2012 |
ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes J Diao, R Liu, Y Rong, M Zhao, J Zhang, Y Lai, Q Zhou, LM Wilz, J Li, ... Nature 520 (7548), 563-566, 2015 | 618 | 2015 |
Molecular basis for amyloid-β polymorphism JP Colletier, A Laganowsky, M Landau, M Zhao, AB Soriaga, ... Proceedings of the National Academy of Sciences 108 (41), 16938-16943, 2011 | 460 | 2011 |
Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis Q Zhou, Y Lai, T Bacaj, M Zhao, AY Lyubimov, M Uervirojnangkoorn, ... Nature 525 (7567), 62-67, 2015 | 349 | 2015 |
The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis Q Zhou, P Zhou, AL Wang, D Wu, M Zhao, TC Südhof, AT Brunger Nature 548 (7668), 420-425, 2017 | 307 | 2017 |
Mechanistic insights into the recycling machine of the SNARE complex M Zhao, S Wu, Q Zhou, S Vivona, DJ Cipriano, Y Cheng, AT Brunger Nature 518 (7537), 61-67, 2015 | 297 | 2015 |
Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity PN Cheng, C Liu, M Zhao, D Eisenberg, JS Nowick Nature chemistry 4 (11), 927-933, 2012 | 269 | 2012 |
Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18 Y Lai, UB Choi, J Leitz, HJ Rhee, C Lee, B Altas, M Zhao, RA Pfuetzner, ... Neuron 95 (3), 591-607. e10, 2017 | 244 | 2017 |
Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation F Luo, X Gui, H Zhou, J Gu, Y Li, X Liu, M Zhao, D Li, X Li, C Liu Nature structural & molecular biology 25 (4), 341-346, 2018 | 218 | 2018 |
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates C Liu, M Zhao, L Jiang, PN Cheng, J Park, MR Sawaya, A Pensalfini, ... Proceedings of the National Academy of Sciences 109 (51), 20913-20918, 2012 | 213 | 2012 |
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly X Gui, F Luo, Y Li, H Zhou, Z Qin, Z Liu, J Gu, M Xie, K Zhao, B Dai, ... Nature communications 10 (1), 2006, 2019 | 194 | 2019 |
Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta L Jiang, C Liu, D Leibly, M Landau, M Zhao, MP Hughes, DS Eisenberg Elife 2, e00857, 2013 | 158 | 2013 |
Ketones block amyloid entry and improve cognition in an Alzheimer's model JX Yin, M Maalouf, P Han, M Zhao, M Gao, T Dharshaun, C Ryan, ... Neurobiology of aging 39, 25-37, 2016 | 152 | 2016 |
Structural insights into Ubr1-mediated N-degron polyubiquitination M Pan, Q Zheng, T Wang, L Liang, J Mao, C Zuo, R Ding, H Ai, Y Xie, D Si, ... Nature 600 (7888), 334-338, 2021 | 92 | 2021 |
Structural principles of SNARE complex recognition by the AAA+ protein NSF KI White, M Zhao, UB Choi, RA Pfuetzner, AT Brunger Elife 7, e38888, 2018 | 84 | 2018 |
An approach to crystallizing proteins by metal‐mediated synthetic symmetrization A Laganowsky, M Zhao, AB Soriaga, MR Sawaya, D Cascio, TO Yeates Protein Science 20 (11), 1876-1890, 2011 | 79 | 2011 |
Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni B Wang, J Lee, P Li, A Saberi, H Yang, C Liu, M Zhao, PA Newmark Elife 7, e35449, 2018 | 77 | 2018 |
Complexin-1 enhances the on-rate of vesicle docking via simultaneous SNARE and membrane interactions J Diao, DJ Cipriano, M Zhao, Y Zhang, S Shah, MS Padolina, ... Journal of the American Chemical Society 135 (41), 15274-15277, 2013 | 75 | 2013 |
Mechanistic insight into substrate processing and allosteric inhibition of human p97 M Pan, Y Yu, H Ai, Q Zheng, Y Xie, L Liu, M Zhao Nature structural & molecular biology 28 (7), 614-625, 2021 | 71 | 2021 |
Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative M Pan, Q Zheng, Y Yu, H Ai, Y Xie, X Zeng, C Wang, L Liu, M Zhao Nature Communications 12 (1), 121, 2021 | 70 | 2021 |