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Minglei Zhao
Minglei Zhao
Dirección de correo verificada de uchicago.edu - Página principal
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Atomic view of a toxic amyloid small oligomer
A Laganowsky, C Liu, MR Sawaya, JP Whitelegge, J Park, M Zhao, ...
Science 335 (6073), 1228-1231, 2012
6212012
ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes
J Diao, R Liu, Y Rong, M Zhao, J Zhang, Y Lai, Q Zhou, LM Wilz, J Li, ...
Nature 520 (7548), 563-566, 2015
6182015
Molecular basis for amyloid-β polymorphism
JP Colletier, A Laganowsky, M Landau, M Zhao, AB Soriaga, ...
Proceedings of the National Academy of Sciences 108 (41), 16938-16943, 2011
4602011
Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis
Q Zhou, Y Lai, T Bacaj, M Zhao, AY Lyubimov, M Uervirojnangkoorn, ...
Nature 525 (7567), 62-67, 2015
3492015
The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis
Q Zhou, P Zhou, AL Wang, D Wu, M Zhao, TC Südhof, AT Brunger
Nature 548 (7668), 420-425, 2017
3072017
Mechanistic insights into the recycling machine of the SNARE complex
M Zhao, S Wu, Q Zhou, S Vivona, DJ Cipriano, Y Cheng, AT Brunger
Nature 518 (7537), 61-67, 2015
2972015
Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity
PN Cheng, C Liu, M Zhao, D Eisenberg, JS Nowick
Nature chemistry 4 (11), 927-933, 2012
2692012
Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18
Y Lai, UB Choi, J Leitz, HJ Rhee, C Lee, B Altas, M Zhao, RA Pfuetzner, ...
Neuron 95 (3), 591-607. e10, 2017
2442017
Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation
F Luo, X Gui, H Zhou, J Gu, Y Li, X Liu, M Zhao, D Li, X Li, C Liu
Nature structural & molecular biology 25 (4), 341-346, 2018
2182018
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates
C Liu, M Zhao, L Jiang, PN Cheng, J Park, MR Sawaya, A Pensalfini, ...
Proceedings of the National Academy of Sciences 109 (51), 20913-20918, 2012
2132012
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
X Gui, F Luo, Y Li, H Zhou, Z Qin, Z Liu, J Gu, M Xie, K Zhao, B Dai, ...
Nature communications 10 (1), 2006, 2019
1942019
Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta
L Jiang, C Liu, D Leibly, M Landau, M Zhao, MP Hughes, DS Eisenberg
Elife 2, e00857, 2013
1582013
Ketones block amyloid entry and improve cognition in an Alzheimer's model
JX Yin, M Maalouf, P Han, M Zhao, M Gao, T Dharshaun, C Ryan, ...
Neurobiology of aging 39, 25-37, 2016
1522016
Structural insights into Ubr1-mediated N-degron polyubiquitination
M Pan, Q Zheng, T Wang, L Liang, J Mao, C Zuo, R Ding, H Ai, Y Xie, D Si, ...
Nature 600 (7888), 334-338, 2021
922021
Structural principles of SNARE complex recognition by the AAA+ protein NSF
KI White, M Zhao, UB Choi, RA Pfuetzner, AT Brunger
Elife 7, e38888, 2018
842018
An approach to crystallizing proteins by metal‐mediated synthetic symmetrization
A Laganowsky, M Zhao, AB Soriaga, MR Sawaya, D Cascio, TO Yeates
Protein Science 20 (11), 1876-1890, 2011
792011
Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni
B Wang, J Lee, P Li, A Saberi, H Yang, C Liu, M Zhao, PA Newmark
Elife 7, e35449, 2018
772018
Complexin-1 enhances the on-rate of vesicle docking via simultaneous SNARE and membrane interactions
J Diao, DJ Cipriano, M Zhao, Y Zhang, S Shah, MS Padolina, ...
Journal of the American Chemical Society 135 (41), 15274-15277, 2013
752013
Mechanistic insight into substrate processing and allosteric inhibition of human p97
M Pan, Y Yu, H Ai, Q Zheng, Y Xie, L Liu, M Zhao
Nature structural & molecular biology 28 (7), 614-625, 2021
712021
Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative
M Pan, Q Zheng, Y Yu, H Ai, Y Xie, X Zeng, C Wang, L Liu, M Zhao
Nature Communications 12 (1), 121, 2021
702021
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